Results 131 to 140 of about 23,125 (311)

Exploring 6‐Hydroxy‐3‐Aryl/Heteroarylcoumarins as Promising Candidates Against Trypanosoma cruzi

ChemMedChem, Volume 21, Issue 9, 14 May 2026.
New therapies are urgently needed for Chagas disease, and screening of 6‐hydroxy‐3‐aryl/heteroarylcoumarin derivatives identified highly selective compounds with potent activity against T. cruzi. In particular, derivative 1f showed submicromolar trypomastigote potency, dual‐stage activity, and inhibition of amastigote‐to‐trypomastigote differentiation,
C. N. Pereira, L. da Silva Lara, S. da Costa Lanera, T. Pérez de Souza, M. C. de Souza Pereira, G. L. Delogu, M. Silva dos Santos, M. J. Matos   +7 more
wiley   +1 more source

Avaliação da atividade terapêutica do albendazol sobre infecções experimental e humana pela Hymenolepis nana Evaluation of therapeutic activity of albendazole against experimental and human infection by Hymenolepis nana

Revista do Instituto de Medicina Tropical de São Paulo, 1990
Com o intuito de demarcar convenientemente o espectro de atividade do albendazol, no que diz respeito às helmintíases intestinais, foram efetuadas observações referentes à himenolepíase causada por Hymenolepis nana.
Vicente Amato Neto, Antonio Augusto Baillot Moreira, Graça Maria Pinto Ferreira, Sérgio Antonio Barbosa do Nascimento, Luís Matsubara, Rubens Campos, Pedro Luiz Silva Pinto   +6 more
doaj   +1 more source

Prevalence of intestinal protozoa infection among school-aged children on Pemba Island, Tanzania, and effect of single-dose albendazole, nitazoxanide and albendazole-nitazoxanide. [PDF]

, 2013
Pathogenic intestinal protozoa infections are common in school-aged children in the developing world and they are frequently associated with malabsorption syndromes and gastrointestinal morbidity.
Albonico, Marco, Ali, Said M, Ame, Shaali M, Bogoch, Isaac I, Keiser, Jennifer, Marti, Hanspeter, Speich, Benjamin, Utzinger, Jürg   +7 more
core   +3 more sources

Computational Design of Azole Derivatives as Multifunctional Agents for Alzheimer's Disease

Applied Organometallic Chemistry, Volume 40, Issue 5, May 2026.
A series of 19 azole derivatives were evaluated using bioinformatic tools and density functional theory in the context of multifunctional agents for Alzheimer's disease and were classified as potential antioxidant, distributor, and suppressor agents. ABSTRACT Alzheimer's disease (AD) is the most common form of dementia, characterized by multifactorial ...
Nicolás Puentes‐Díaz, Yair Alvarez‐Ricardo, Diego Chaparro, Areli Flores‐Gaspar, John Hurtado, Jorge Alí‐Torres   +5 more
wiley   +1 more source

Contemporary Applications of Chemical Libraries for Drug Discovery and Methods for Their Synthesis

ChemistryEurope, Volume 4, Issue 5, May 2026.
Screening of chemical libraries has over the past decades become a cornerstone of drug discovery. Today, a broad range of chemical libraries exist but they are often not well described in terms of diversity. This review describes current efforts which aim to visualize chemical diversity in compound collections and discuss current trends in synthetic ...
Tobias N. Hansen, Nils J. V. Hansen
wiley   +1 more source

Treatment of Leishmania infantum Infections in Dogs

Microorganisms
Dogs are reservoir hosts of the zoonotic parasite Leishmania infantum, the causative agent of canine leishmaniosis. Antiparasitic drugs that are commonly used in dogs include allopurinol, miltefosine, and meglumine antimoniate.
Melanie Kaempfle, Katrin Hartmann, Michèle Bergmann   +2 more
doaj   +1 more source

Synthesis, Characterization and Nanoformulation of Novel Sulfonamide-1,2,3-triazole Molecular Conjugates as Potent Antiparasitic Agents [PDF]

, 2022
Faizah S. Aljohani, Nadjet Rezki, Mohamed Reda Aouad, Bassma H. Elwakil, Mohamed Hagar, Eman Sheta, Nermine Mogahed Fawzy Hussein Mogahed, Sanaa K. Bardaweel, Nancy Abd‐elkader Hagras   +8 more
openalex   +1 more source

Temporal Trends in the Epidemiology of Eating Disorders Between 2000 and 2022: A Danish Register Study of Their Incidence and Comorbidities

European Eating Disorders Review, Volume 34, Issue 3, Page 749-769, May 2026.
ABSTRACT Background Eating disorders are debilitating illnesses that often co‐occur with other psychiatric disorders and somatic diseases. Evidence indicates that the incidence of eating disorders has been increasing. We first examine the landscape of EDs over time, including the COVID‐19 period, via assessing the incidence of anorexia nervosa (AN ...
Nadia Micali, Helena L. Davies, Heidi Jeannet Graff, Laust H. Mortensen, Emilie R. Hegelund   +4 more
wiley   +1 more source

Integrative Insights Into Bioactive Peptides in Milk Fermented With Autochthonous and Commercial Cultures Using High‐Throughput Peptidomics and Machine Learning

Food Frontiers, Volume 7, Issue 3, May 2026.
This article highlights the crucial role of starter culture selection in shaping the peptide profile of fermented dairy drinks. Using high‐throughput peptidome profiling, the study demonstrates that different starter cultures yield distinct quantities and types of bioactive peptides, with excessive microbial combinations potentially reducing peptide ...
Martina Banić, Ana Butorac, Katarina Butorac, Blaženka Kos, Andreja Leboš Pavunc, Jagoda Šušković, Jasna Novak   +6 more
wiley   +1 more source

Scabies Outbreak in Pediatric Populations of Bangladesh: A Perspective on Therapeutic Management, Risk Factors, and Public Health Implications

Health Science Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background and Aims Scabies remains a major cause of morbidity among Bangladeshi children, particularly in overcrowded and resource‐limited settings. This perspective synthesizes current evidence to contextualize the surge of pediatric scabies outbreaks reported across Bangladesh in 2025.
Hemayet Hossain, Md. Al Muktadir, Snigdha Sharmin Binte Sayeed, Sojib Ahmed, Md. Hasan Ali, Khadiza Akter Brishty, Md. Shahidur Rahman Chowdhury, Md. Mahfujur Rahman   +7 more
wiley   +1 more source