Results 121 to 130 of about 23,125 (311)

Anti-Trypanosoma cruzi action of a new benzofuran derivative based on amiodarone structure [PDF]

, 2018
Chagas disease is a neglected tropical affection caused by the protozoan parasite Trypanosoma cruzi. There is no current effective treatment since the only two available drugs have a limited efficacy and produce side effects.
Benaim, Gustavo, Hejchman, Elżbieta, Hernández Rodríguez, Vanessa, Pinto Martinez, Andrea, Rodríguez Durán, Jessica Jenireth   +4 more
core   +1 more source

Edulitin 2, a Ribotoxin‐Like Protein From Boletus edulis That Triggers Apoptosis in Colon Cancer Cells While Preserving the Integrity of the Intestinal Microbiota

eFood, Volume 7, Issue 3, June 2026.
Edulitin 2 is a ribotoxin‐like protein exhibiting a potent antiproliferative activity towards Caco‐2 and HT29 cells by programmed cell death. However, edulitin 2 does not affect gut microbiota growth, despite damaging fungal ribosomes. ABSTRACT Porcini (Boletus edulis Bull.) are a reservoir of pharmacological biomolecules with health‐promoting ...
Massimo Bortolotti, Sara Ragucci, Federica Falà, Anella Saggese, Francesco Biscotti, Ylenia De Luca, Nicola Landi, Paolo V. Pedone, Andrea Bolognesi, Ezio Ricca, Letizia Polito, Antimo Di Maro   +11 more
wiley   +1 more source

Oxidative Stress in the Tumor Immune Microenvironment: Mechanisms and Therapeutic Perspectives

MedComm – Oncology, Volume 5, Issue 2, June 2026.
Oxidative stress is involved in several key processes in cancer, including redox regulation, DNA damage, post‐translational modifications, transcriptional regulation, epigenetic modifications, metabolic reprogramming, cell death, and immune modulation. These mechanisms collectively influence tumor progression, immune evasion, and therapeutic responses,
Zhen Wang, Bowen Li, Pan Tang, Fanchen Yan, Shuxin Wang, Guiying Leng, Panduo Dawa, Yuansi Chen, Yihan Guo, Pan Yang, Yi Li, Siyu Liu, Erdan Dong, Siyuan Qin, Zhoufeng Wang   +14 more
wiley   +1 more source

Pumpkin seed oil: unveiling its potential in controlling inflammation and pathogenicity during experimental trichinellosis

BMC Veterinary Research
Background This study aimed to investigate the antiparasitic and anti-inflammatory potential of pumpkin seed oil in mice infected with Trichinella spiralis by demonstrating its impact on MMP-9 expression and pathogenesis during the intestinal and ...
Sara Salah Abdel-Hakeem, Sulaiman Mohammed Alnasser, Alotaibi Meshal, Mahmoud Abdel-Zaher Abdel-Samiee, Mohamed Salah Eldin Youssef, Shimaa Hamdi Abd Elsadek, Salwa Mahmoud Abd-Elrahman   +6 more
doaj   +1 more source

Metabolomics guides rational development of a simplified cell culture medium for drug screening against Trypanosoma brucei [PDF]

, 2013
n vitro culture methods underpin many experimental approaches to biology and drug discovery. The modification of established cell culture methods to make them more biologically relevant or to optimize growth is traditionally a laborious task.
Alsford, Alsford, Baltz, Barrett, Berger, Berger, Bitonti, Bowling, Bradley, Breitling, Brun, Brunda Nijagal, Creek, Creek, Creek, Darren J. Creek, de Koning, Dong-Hyun Kim, Drexler, Duszenko, Duszenko, Federico Rojas, Geary, Haanstra, Hasne, Hirumi, Hirumi, Hirumi, Jacobs, Keith R. Matthews, Kuettel, Kwon, Lanteri, Lanteri, Mashego, Michael P. Barrett, Mäser, Räz, Saunders, Scalbert, Scheltema, Scheltema, Seed, Sienkiewicz, Smith, Sumner, Sykes, t'Kindt, Tautenhahn, Vincent, Wang, Ward, Wilson, Winder, Wishart, Wu, Zaboikin, Zang, Zhang   +58 more
core   +2 more sources

Infectious Diseases Management in Small‐Scale Freshwater Aquaculture in West Africa: Lessons for Low‐ and Middle‐Income Countries

Reviews in Aquaculture, Volume 18, Issue 3, June 2026.
ABSTRACT Infectious diseases are an increasing threat to food security, small‐scale livelihoods and the sustainability of aquaculture in low‐ and middle‐income countries (LMICs). In sub‐Saharan Africa, aquaculture is expanding rapidly but production systems often remain fragile.
Mame Boucar Diouf, Robane Faye, Ahou Rachel Koumi, Nounagnon Darius Tossavi, Enoutchy Fabrice Bouah, Ephigénie Ndew Dione, El Hadji Malick Sy Camara, Kadjo Henri Joel Niamien, Ué Clavier Zéa Bi, Atto Delphin Kouadio, El Hadji Papa Abdourahim Sy, Thérèse Adeline Fatou Gomis, Paul Mamadou Ndour, Konan Jean Baptiste Djanhan, Samba Diouf, Jean‐Christophe Avarre, Jean Fall, Elie Montchowui, Koffi Charles Boussou   +18 more
wiley   +1 more source

Healing and leishmanicidal activity of Zanthoxylum rhoifolium Lam.

Frontiers in Chemistry
Zanthoxylum rhoifolium is used in folk medicine as an antiparasitic agent. Therefore, this study evaluated the phytochemical aspects and biological activities of Z. rhoifolium. For this, the ethanolic extract (EE) was obtained by macerating the peel with
Juliana Correa-Barbosa, Juliana Correa-Barbosa, Heliton Patrick Cordovil Brígido, Heliton Patrick Cordovil Brígido, Bibiana Franzen Matte, Paloma Santos De Campos, Marcelo Lazzaron Lamers, Daniele Ferreira Sodré, Pedro Henrique Costa Nascimento, Gleison Gonçalves Ferreira, Valdicley Vieira Vale, Andrey Moacir do Rosário Marinho, José Edson De Sousa Siqueira, Márlia Regina Coelho-Ferreira, Marta Chagas Monteiro, Marta Chagas Monteiro, Marta Chagas Monteiro, Marta Chagas Monteiro, Maria Fâni Dolabela, Maria Fâni Dolabela   +19 more
doaj   +1 more source

Assessment of antitumoral and antimicrobial effects of a maslinic acid derivative [PDF]

Research and Clinical Medicine, 2016
INTRODUCTION Maslinic acid, a naturally occurring triterpene, has been reported to possess several therapeutic effects including antioxidant, anti-inflammatory and antiparasitic properties.
Ioana Z. Pavel , Corina Danciu, Delia Muntean , Cristina A. Dehelean, René Csuk , Danina M. Muntean   +5 more
doaj  

Aryloxyethyl thiocyanates are potent growth inhibitors of Trypanosoma cruzi and Toxoplasma gondii [PDF]

, 2015
As a part of our project aimed at searching new safe chemotherapeutic agents against parasitic diseases, several compounds structurally related to the antiparasitic agent WC-9 (4-phenoxyphenoxyethyl thiocyanate), which were modified at the terminal ...
Chao, Maria Noelia, Docampo, Roberto, Exeni Matiuzzi, Carolina, Li, Catherine, Moreno, Silvia N. J., Rodriguez, Juan Bautista, Storey, Melissa, Szajnman, Sergio Hernan   +7 more
core   +1 more source

Plant‐Derived Treatments for Monogenean Parasites in Farmed Fish: A Systematic Review and Meta‐Analysis

Reviews in Aquaculture, Volume 18, Issue 3, June 2026.
ABSTRACT Monogeneans are among the most problematic ectoparasites in finfish aquaculture. Plant‐derived compounds have been widely explored as therapeutic agents, yet their efficacy and safety have not been quantitatively synthesized across studies. This study provides a meta‐analysis of plant‐based treatments against monogeneans, integrating 453 in ...
Francisco Neptalí Morales‐Serna
wiley   +1 more source