Results 101 to 110 of about 23,125 (311)

Selective anti-malarial minor groove binders [PDF]

, 2016
A set of 31 DNA minor groove binders (MGBs) with diverse structural features relating to both physical chemical properties and DNA binding sequence preference has been evaluated as potential drugs to treat Plasmodium falciparum infections using a ...
Avery, Vicky M., Duffy, Sandra, Khalaf, Abedawn I., Scott, Fraser J., Suckling, Colin J.   +4 more
core   +1 more source

Hypersensitivity to Excipients in Drugs: An EAACI Position Paper

Allergy, EarlyView.
ABSTRACT Drugs contain active pharmaceutical ingredients and excipients, compounds which enhance the pharmacokinetics, stability and palatability of the pharmaceutical formulation. While most drug hypersensitivity reactions (DHR) are caused by active ingredients, excipients may also be involved.
Lene H. Garvey, Knut Brockow, Annick Barbaud, Charlotte G. Mortz, Gianfranco Calogiuri, Asli Gelincik, Osman O. Yeğit, Alla Nakonechna, Annette Wagner, Rik Schrijvers, Toon Ieven   +10 more
wiley   +1 more source

Insights into Chagas treatment based on the potential of bacteriocin AS-48

International Journal for Parasitology: Drugs and Drug Resistance, 2019
Chagas disease caused by the protozoan parasite Trypanosoma cruzi represents a significant public health problem in Latin America, affecting around 8 million cases worldwide.
Rubén Martín-Escolano, Rubén Cebrián, Javier Martín-Escolano, Maria J. Rosales, Mercedes Maqueda, Manuel Sánchez-Moreno, Clotilde Marín   +6 more
doaj   +1 more source

Novel cruzain inhibitors for the treatment of Chagas' disease. [PDF]

, 2012
The protozoan parasite Trypanosoma cruzi, the etiological agent of Chagas' disease, affects millions of individuals and continues to be an important global health concern.
Arkin, Michelle R, Doak, Allison, Durrant, Jacob D, Keränen, Henrik, McCammon, J Andrew, Ratnam, Joseline, Rogers, Kathleen E   +6 more
core   +1 more source

Epicutaneous and Drug Provocation Testing in Severe Cutaneous Adverse Reactions: A 20‐Year Single‐Centre Experience

Contact Dermatitis, EarlyView.
This study provides reassuring evidence in favour of early skin testing in patients with SCARs, argues against the necessity of a 6‐month delay, and underscores the pivotal role of oral provocation tests in the safe reintroduction of essential therapies. ABSTRACT Background Identifying and discontinuing the offending drug(s) in severe cutaneous adverse
Zohra Chadli, Khadija Mansour, Ghada Jaouahdou, Manel Ben Belgacem, Yosra Soua, Nadia Ben Fredj, Jameleddine Zili, Haifa Ben Romdhane, Karim Aouam   +8 more
wiley   +1 more source

Vectors and Vector‐Borne Diseases: Biology, Epidemiology and Integrated Control Strategies

Journal of Applied Entomology, EarlyView.
ABSTRACT Vector‐Borne Diseases (VBDs), transmitted by arthropods such as mosquitoes, ticks, fleas and sandflies, represent a significant threat to global health. These diseases can be caused by a variety of pathogens, including bacteria, viruses, protozoa, and helminths.
Roberta Rinaldi, Carmen Scieuzo, Federica De Stefano, Luca Masucci, Patrizia Falabella   +4 more
wiley   +1 more source

The effects of LED Spectra on synthesis of antiparasitic bioactive compound in Eurycoma longifolia hairy root culture against Blastocystis Sp

Scientific Reports
Eurycoma longifolia (also known as Tongkat Ali) is one of the valuable medicinal plants frequently used as traditional medicine in Malaysia. Its alkaloids and quassinoids reportedly confers antiparasitic activities. The effect of different Light Emitting
Mahmoud Ali Khalaf Abushattal, Sani Sale, Sreeramanan Subramaniam, Mohamad Nurul Azmi Mohamad Taib, Arutchelvan Rajamanikam, Farah Haziqa Meor Termizi, Nor Hasnida Hassan, Mohamad Fadhli Mad’ Atari   +7 more
doaj   +1 more source

Antiparasitic and antimicrobial activity of Ipomoea palmata against Toxoplasma gondii and Staphylococcus aureus: correlation with major phenolics identified by HPLC

Artificial Cells, Nanomedicine, and Biotechnology
Toxoplasma gondii, a protozoan parasite found in water sources, causes toxoplasmosis, with no current protocols for inactivating its oocysts in water.
Amira Mira, Tariq M. Aljarba, Fatma M. Abdel Bar, Rehab Ahmed, Walaa A. Negm, Engy Elekhnawy, Hosam M. El-Seadawy, Eman A. Elmorsy, Salwa S. Younis   +8 more
doaj   +1 more source

Bath Treatments With Emamectin Benzoate Control Dactylogyrideans Infecting Colossoma macropomum Gills Without Altering Physiology of This Host Fish

Journal of Fish Diseases, EarlyView.
ABSTRACT Intensification of fish aquaculture worldwide has led to severe problems of diseases caused by parasitic dactylogyrideans. In this study, the anti‐dactylogyridean efficacy of treating Colossoma macropomum with baths of emamectin benzoate (EMB) was investigated for the first time, along with the effects of this treatment on the haematology and ...
Raimundo Rosemiro de Jesus Baia, Marcela Nunes Videira, Amanda Mendes Pacheco, Eliane Tie Oba Yoshioka, Marcos Tavares‐Dias   +4 more
wiley   +1 more source

Evaluation of the hydroalcoholic extract of Clarisia racemosa as an antiparasitic agent: an in vitro approach. [PDF]

3 Biotech, 2023
da Cruz Filho IJ, Duarte DMFA, Marques DSC, da Rocha JVR, Diniz EGM, Brayner FA, Alves LC, de Azevedo Albuquerque MCP, de Lima Aires A, Nogueira F, de Lima MDCA.   +10 more
europepmc   +1 more source