Results 61 to 70 of about 1,521,556 (235)

Inclusion Complexations of Levamisole and Cocaine With Molecular Baskets. Fluorescence Displacement Assay for Detection of Cocaine and Its Adulterant Levamisole in Aqueous Media

Chemistry – A European Journal, EarlyView.
Levamisole is a common adulterant found in street‐distributed cocaine. Molecular baskets have been shown to form stable inclusion complexes with both substances. While levamisole inserts its benzene into the basket's cavity, cocaine utilizes its bicyclic ring for encapsulation.
Christopher T. Mortensen, Carson E. Ward, Nitesh Kumar, Logan Willemann, Ryan Lutz, Kailey Hughes, Zheng Zheng, Jovica D. Badjić   +7 more
wiley   +1 more source

Synthesis of Naphthoquinones by Pd‐Catalyzed Heck–Matsuda Arylation of Lapachol

European Journal of Organic Chemistry, EarlyView.
Direct Heck–Matsuda arylation of lapachol enables the efficient synthesis of diverse naphthoquinones under homogeneous and heterogeneous palladium catalysis. The methodology features broad substrate scope, gram‐scale applicability, and provides a practical platform for quinone diversification.
Breno U. de Abreu, Renata G. Almeida, Ana L. C. Silveira, Leonardo A. Matos, Willian X. C. Oliveira, Maria H. Araujo, Victor F. S. Ramos, Rubem F. S. Menna‐Barreto, Chandrakant B. Nichinde, Felipe Fantuzzi, Edmond Gravel, Eric Doris, Eufrânio N. da Silva Júnior, Guilherme A. M. Jardim   +13 more
wiley   +1 more source

Investigation of Antiparasitic Effect of Juniperus communis L. Fruits Extracts [PDF]

Objective: Juniperus communis (J. communis) (common juniper) is a plant that has been used for medicinal purposes for centuries. This study aims to evaluate the antiparasitic effects of ethanol, methanol, chloroform, and water extracts of J.
İbrahim Çavuş, Ahmet Özbilgin, Yener Özel, Varol Tunalı, Çavuş, İbrahim, Tunalı, Varol, Hüsniye Kayalar, Yereli, Kor, Kayalar, Hüsniye, ÖzbiLgin, Ahmet, Kor Yereli, Özel, Yener   +11 more
core   +1 more source

ER‐Localized Deadenylase PNLDC1 Suppresses Colorectal Cancer Progression by Targeting the mRNA Decay of TUBB4B

Exploration, EarlyView.
The deficiency of PNLDC1 exacerbates the advancement of CRC. PNLDC1 interacts with TUBB4B mRNA to regulate the p53–p21–CDK2–cyclin E2 pathway, thereby influencing the G2/M phase of the cell cycle. ABSTRACT Colorectal cancer (CRC) remains a leading cause of cancer‐related mortality, highlighting the urgent need for novel therapeutic strategies.
Lexin Liu, Yuelin Guan, Yuzhou Qin, Guiping Chen, Guozhen Wang, Xiang Yan, Xue Li, Lei Sun, Wei Yu, Shi Ouyang, Zhichao Ma, Zihao Xu, Zhongkai Cao, Fan Yu, Tong Zhou, Ziyou Luo, Xiangjun Chen, Yongbin Yan, Lidan Hu   +18 more
wiley   +1 more source

Coalescing beneficial host and deleterious antiparasitic actions as an antischistosomal strategy

eLife, 2018
Conventional approaches for antiparasitic drug discovery center upon discovering selective agents that adversely impact parasites with minimal host side effects.
John D Chan, Timothy A Day, Jonathan S Marchant   +2 more
doaj   +1 more source

Optimising the Eco‐Friendly Extraction of Carotenoids From Gac Fruit: A Sustainable Solution for Natural Red Food Colourants

Food Chemistry International, EarlyView.
Gac fruit's high carotenoid content, especially in the aril, makes it an excellent natural red pigment source for food applications, offering a safer alternative to synthetic dyes. Ethanol extraction achieved the highest overall pigment recovery (89.53%), whereas ethyl lactate extraction yielded the highest levels of total carotenoids, β‐carotene ...
N. Netravati, S. Gomez, B. Pathrose, A. Suma, J. Hosamani   +4 more
wiley   +1 more source

N-(4-Methoxyphenyl)Pentanamide, a Simplified Derivative of Albendazole, Displays Anthelmintic Properties against the Nematode Toxocara canis

Microbiology Spectrum, 2022
Infections caused by parasitic helminths have enormous health, social, and economic impacts worldwide. The treatment and control of these diseases have been dependent on a limited set of drugs, many of which have become less effective, necessitating the ...
Taís C. Silva, Ana C. Mengarda, Bruna L. Lemes, Susana A. Z. Lescano, Dalete Christine S. Souza, João Henrique G. Lago, Josué de Moraes   +6 more
doaj   +1 more source

Phytochemistry, Chemotypic Diversity and Antimicrobial Potential of Essential Oils From Native Aromatic Plants of the Americas: A Systematic Review

Flavour and Fragrance Journal, EarlyView.
This review bridges ancestral indigenous knowledge with modern pharmacology, summarizing the phytochemistry and antimicrobial properties of essential oils from seven native American species. It highlights their significant activity against bacterial, fungal and parasitic pathogens, emphasizing their potential as sustainable therapeutic and agricultural
Arley Rey Páez, Mozaniel Santana de Oliveira, João Paulo Viana Leite   +2 more
wiley   +1 more source

Safety of Prenatal Anti‐Infective Use and Offspring Outcomes: A Panoramic Assessment by Indication, Drug Class, and Exposure Characteristics

iMetaMed, EarlyView.
Based on the comprehensive, panoramic assessment of the safety of prenatal anti‐infective use across indications, drug classes, and exposure characteristics, potential safety signals associated with prenatal exposure to several widely used anti‐infective drug classes were identified, including macrolides, metronidazole, tetracyclines, sulfonamides ...
Wenling Wang, Yuezhen Li, Chunrong Liu, Chen Chen, Meng Chen, Lehana Thabane, Xin Sun, Jing Tan   +7 more
wiley   +1 more source

Research progress of albendazole medicinal preparations

上海师范大学学报. 自然科学版
Albendazole(ABZ) is a benzimidazole derivative which was mainly used as an antiparasitic drug to treat nematode diseases such as hookworm, roundworm, and trichuris, as well as cysticercosis and echinococcosis.
JIA Cheng, HOU Huiliang, NING Bo, LI Yingding, CHENG Tanyu   +4 more
doaj   +1 more source