Results 41 to 50 of about 1,521,556 (235)

Progress in Redirecting Antiparasitic Drugs for Cancer Treatment

, 2021
Haoyang Huang,1 Qing He,2– 5 Binghua Guo,6 Xudong Xu,7 Yinjuan Wu,2– 5 Xuerong Li2– 5 1Department of Clinical Medicine, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, Guangdong, 510080, People’s Republic of China;
Li X, Huang H, He Q, Guo B, Xu X, Wu Y
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New drugs against trypanosomatid parasites : rediscovery of fexinidazole [PDF]

, 2014
Neglected tropical diseases (NTDs) are a group of communicable diseases mostly affecting people in developing countries. These diseases are responsible for a major part of the global morbidity, mortality and poverty. There is no doubt that the well-being
Kaiser, Marcel
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Chemistry and Biology of Macrolide Antiparasitic Agents

, 2016
Macrolide antibacterial agents inhibit parasite proliferation by targeting the apicoplast ribosome. Motivated by the long-term goal of identifying antiparasitic macrolides that lack antibacterial activity, we have systematically analyzed the structure ...
Chaitan Khosla (24135), Younjoo Lee (1823023), Hong Fu (37557), Sandeep Ravindran (256511), John C. Boothroyd (9252), William R. Roush (361839), Jun Yong Choi (290863), Colin Harvey (2204668)   +7 more
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Antiplasmodial Activity of p-Substituted Benzyl Thiazinoquinone Derivatives and Their Potential against Parasitic Infections

Molecules, 2020
Malaria is a life-threatening disease and, what is more, the resistance to available antimalarial drugs is a recurring problem. The resistance of Plasmodium falciparum malaria parasites to previous generations of medicines has undermined malaria control ...
Marcello Casertano, Marialuisa Menna, Caterina Fattorusso, Nicoletta Basilico, Silvia Parapini, Marco Persico, Concetta Imperatore   +6 more
doaj   +1 more source

Plant active components – a resource for antiparasitic agents?

, 2005
Plant essential oils (and/or active components) can be used as alternatives or adjuncts to current antiparasitic therapies. Garlic oil has broad-spectrum activity against Trypanosoma, Plasmodium, Giardia and Leishmania, and Cochlospermum planchonii and ...
Fyfe, Lorna, Smith, Huw, Anthony, Jean-Paul   +2 more
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Larrea tridentata: A novel source for anti-parasitic agents active against Entamoeba histolytica, Giardia lamblia and Naegleria fowleri.

PLoS Neglected Tropical Diseases, 2017
Protozoan parasites infect and kill millions of people worldwide every year, particularly in developing countries where access to clean fresh water is limited.
Bharat Bashyal, Linfeng Li, Trpta Bains, Anjan Debnath, Daniel V LaBarbera   +4 more
doaj   +1 more source

Synthesis and Antiplasmodial Activity of Novel Bioinspired Imidazolidinedione Derivatives

Biomolecules, 2020
Malaria is an enormous threat to public health, due to the emergence of Plasmodium falciparum resistance to widely-used antimalarials, such as chloroquine (CQ).
Anna Jaromin, Anna Czopek, Silvia Parapini, Nicoletta Basilico, Ernest Misiak, Jerzy Gubernator, Agnieszka Zagórska   +6 more
doaj   +1 more source

Exploring bioactive molecules released during inter- and intraspecific competition: A paradigm for novel antiparasitic drug discovery and design for human use

Current Research in Parasitology and Vector-Borne Diseases
Many antiparasitic drugs have become obsolete and ineffective in treating parasitic diseases. This ineffectiveness arises from parasite drug resistance, high toxicity, and low drug efficacy.
Pichet Ruenchit
doaj   +1 more source

Anti-BioEn: An advanced framework for accurate bioactive agent classification based on hybrid models and graph feature encoding method [PDF]

BIO Web of Conferences
Bioactive agents are compounds that have an influence on human beings, organs, or tissues. These agents, which might be found in both natural and synthetic chemicals, are able to interact with biological systems and produce a variety of therapeutic or ...
Shaon Shazzad Hossain, Sultan Fahim, Karim Tasmin, Akter Shapna   +3 more
doaj   +1 more source

Evidence-based indications for ivermectin in parasitic diseases: An integrated approach to context and challenges in Peru

Parasite Epidemiology and Control, 2023
Ivermectin has emerged as a therapeutic option for various parasitic diseases, including strongyloidiasis, scabies, lice infestations, gnathostomiasis, and myiasis.
Virgilio E. Failoc-Rojas, Heber Silva-Díaz, Jorge L. Maguiña, Alfonso J. Rodriguez-Morales, Cristian Díaz-Velez, Moises Apolaya-Segura, Mario J. Valladares-Garrido   +6 more
doaj   +1 more source