Results 41 to 50 of about 32,131 (285)

Drugs from the Cloudforest: The Search for New Medicines from Monteverde, Costa Rica

Natural Product Communications, 2011
The University of Alabama in Huntsville Natural Products Research Group has been investigating the phytopharmaceutical potential of tropical rainforest higher plants from the Monteverde region of northwestern Costa Rica for the past twenty years.
William N. Setzer
doaj   +1 more source

Analysis of the range of drugs registered in the Russian Federation to control parasitic infections in pigs

Российский паразитологический журнал, 2023
The purpose of the research is the analysis of the range of antiparasitic drugs for pig breeding as registered in the Russian Federation and included in the State Register of Medicinal Products for Veterinary Use.The control of parasitic diseases is an ...
T. V. Gerunov, V. I. Dorozhkin, L. K. Gerunova, M. N. Gonochova, Ya. O. Kryuchek, A. A. Tarasenko, E. A. Chigrinski   +6 more
doaj   +1 more source

Functional Assessment of 2,177 U.S. and International Drugs Identifies the Quinoline Nitroxoline as a Potent Amoebicidal Agent against the Pathogen Balamuthia mandrillaris

mBio, 2018
Balamuthia mandrillaris is a pathogenic free-living amoeba that causes a rare but almost always fatal infection of the central nervous system called granulomatous amoebic encephalitis (GAE). Two distinct forms of B.
Matthew T. Laurie, Corin V. White, Hanna Retallack, Wesley Wu, Matthew S. Moser, Judy A. Sakanari, Kenny Ang, Christopher Wilson, Michelle R. Arkin, Joseph L. DeRisi   +9 more
doaj   +1 more source

Synthesis and Antiplasmodial Activity of Novel Bioinspired Imidazolidinedione Derivatives

Biomolecules, 2020
Malaria is an enormous threat to public health, due to the emergence of Plasmodium falciparum resistance to widely-used antimalarials, such as chloroquine (CQ).
Anna Jaromin, Anna Czopek, Silvia Parapini, Nicoletta Basilico, Ernest Misiak, Jerzy Gubernator, Agnieszka Zagórska   +6 more
doaj   +1 more source

Evidence-based indications for ivermectin in parasitic diseases: An integrated approach to context and challenges in Peru

Parasite Epidemiology and Control, 2023
Ivermectin has emerged as a therapeutic option for various parasitic diseases, including strongyloidiasis, scabies, lice infestations, gnathostomiasis, and myiasis.
Virgilio E. Failoc-Rojas, Heber Silva-Díaz, Jorge L. Maguiña, Alfonso J. Rodriguez-Morales, Cristian Díaz-Velez, Moises Apolaya-Segura, Mario J. Valladares-Garrido   +6 more
doaj   +1 more source

In Vitro Screening Test Using Leishmania Promastigotes Stably Expressing mCherry Protein [PDF]

, 2014
Transgenic Leishmania major and Leishmania donovani axenic promastigotes constitutively expressing mCherry were used for in vitro antileishmanial drug screening. This method requires minimal sample manipulation and can be easily adapted to automatic drug
Miguel A. Morales, Vacchina, Paola
core   +2 more sources

Larrea tridentata: A novel source for anti-parasitic agents active against Entamoeba histolytica, Giardia lamblia and Naegleria fowleri.

PLoS Neglected Tropical Diseases, 2017
Protozoan parasites infect and kill millions of people worldwide every year, particularly in developing countries where access to clean fresh water is limited.
Bharat Bashyal, Linfeng Li, Trpta Bains, Anjan Debnath, Daniel V LaBarbera   +4 more
doaj   +1 more source

In vivo nematicidal potential of camel milk on Heligmosomoides polygyrus gastro-intestinal nematode of rodents [PDF]

, 2018
Following our previous fi ndings on the in vitro anthelmintic effect of camel milk on Haemonchus contortus, the current study aimed at investigating its in vivo effect.
Abidi, A., Akkari, H., Alimi, D., Dhibi, M., Maizels, R.M., Rekik, M., Sebai, E.   +6 more
core   +1 more source

Exploring bioactive molecules released during inter- and intraspecific competition: A paradigm for novel antiparasitic drug discovery and design for human use

Current Research in Parasitology and Vector-Borne Diseases
Many antiparasitic drugs have become obsolete and ineffective in treating parasitic diseases. This ineffectiveness arises from parasite drug resistance, high toxicity, and low drug efficacy.
Pichet Ruenchit
doaj   +1 more source

Anti-BioEn: An advanced framework for accurate bioactive agent classification based on hybrid models and graph feature encoding method [PDF]

BIO Web of Conferences
Bioactive agents are compounds that have an influence on human beings, organs, or tissues. These agents, which might be found in both natural and synthetic chemicals, are able to interact with biological systems and produce a variety of therapeutic or ...
Shaon Shazzad Hossain, Sultan Fahim, Karim Tasmin, Akter Shapna   +3 more
doaj   +1 more source