Results 41 to 50 of about 17,058 (185)

Optimising the Eco‐Friendly Extraction of Carotenoids From Gac Fruit: A Sustainable Solution for Natural Red Food Colourants

Food Chemistry International, EarlyView.
Gac fruit's high carotenoid content, especially in the aril, makes it an excellent natural red pigment source for food applications, offering a safer alternative to synthetic dyes. Ethanol extraction achieved the highest overall pigment recovery (89.53%), whereas ethyl lactate extraction yielded the highest levels of total carotenoids, β‐carotene ...
N. Netravati, S. Gomez, B. Pathrose, A. Suma, J. Hosamani   +4 more
wiley   +1 more source

Evaluation of DNA/Chromosome Integrity and Cell Death in Human Metabolically Noncompetent and Competent Cells Exposed to N′‐(3,5‐Difluorobenzylidene)Pyridine‐4‐Carbohydrazide

Journal of Applied Toxicology, EarlyView.
ABSTRACT The N‐acylhydrazone scaffold is recognized as a privileged structure for the design of bioactive substances with increasing applications in medicinal chemistry research. Ensuring the safety of newly developed molecules is a critical step for both human health and environmental protection. Accordingly, this study aimed to evaluate the cytotoxic
Larissa Ribeiro Canuto Santos, Jéssica Natalia Barbosa de Almeida, Camila Cavalleiro Frias, Wanda Pereira Almeida, Edson Luis Maistro   +4 more
wiley   +1 more source

Mediastinal Schistosomiasis in a Patient with HIV and Leprosy: A Case Report [PDF]

Journal of Clinical and Diagnostic Research
Schistosomiasis is a parasitic disease commonly affecting the urinary and gastrointestinal systems, caused by trematode worms of the genus Schistosoma.
Diksha Sabharwal, Asmita Samal, Kalyan Kumar Reddy, Sonali Agarwal   +3 more
doaj   +1 more source

Dual Genotoxic and Antigenotoxic Effects of 3‐Benzoylcoumarins in Mammalian Cells

Journal of Applied Toxicology, EarlyView.
ABSTRACT Coumarins are phenolic compounds widely recognized for their diverse pharmacological activities and have attracted increasing attention as potential chemopreventive agents. In the present study, four known 3‐benzoylcoumarin derivatives [(1), (2), (3), and (4)] were evaluated for their cytotoxic, mutagenic, and antigenotoxic effects in Chinese ...
Leticia Helena Parreira, Evelyn Pinheiro de Mendonça, Aléxia Polo Siqueira, Cleydson Finotti Cordeiro, Elkin José Torres Sierra, Rudy Bonfilio, Diogo Teixeira Carvalho, Pollyanna Francielli de Oliveira   +7 more
wiley   +1 more source

Research progress of albendazole medicinal preparations

上海师范大学学报. 自然科学版
Albendazole(ABZ) is a benzimidazole derivative which was mainly used as an antiparasitic drug to treat nematode diseases such as hookworm, roundworm, and trichuris, as well as cysticercosis and echinococcosis.
JIA Cheng, HOU Huiliang, NING Bo, LI Yingding, CHENG Tanyu   +4 more
doaj   +1 more source

Review of phytochemical and antioxidant properties of Ethiopian medicinal plants

JSFA reports, EarlyView.
Abstract Ethiopia possesses a rich ethnobotanical heritage and diverse medicinal flora that play an important role in traditional healthcare. Many Ethiopian medicinal plants contain bioactive phytochemicals with potential antioxidant properties. This capital of indigenous knowledge has contributed to the documentation of different medicinal plants that
Endalamaw Yihune, Amare Bitew Mekonnen, Getahun Yemata   +2 more
wiley   +1 more source

Amebicides against Acanthamoeba castellanii: The Impact of Organism Models Used in Amebicide Assays

Parasitologia
Acanthamoeba castellanii is a free-living amoeba capable of causing keratitis in humans, with most cases related to contact lens wearers and surgical procedures. In addition, A.
Leonardo Fernandes Geres, Elena Sartori, João Marcos dos Santos Neves, Danilo Ciccone Miguel, Selma Giorgio   +4 more
doaj   +1 more source

Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future

Medicinal Research Reviews, EarlyView.
ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley   +1 more source

A Case of Creeping Disease Caused by Gnathostoma in a Pregnant Woman Treated With Ivermectin

Clinical Case Reports
We encountered a case of gnathostomiasis in a pregnant woman; she was successfully treated using ivermectin, and the baby was delivered without complications.
Sonoka Uchida, Hidetoshi Maruyama, Yoshihito Yokoyama   +2 more
doaj   +1 more source

Coalescing beneficial host and deleterious antiparasitic actions as an antischistosomal strategy

eLife, 2018
Conventional approaches for antiparasitic drug discovery center upon discovering selective agents that adversely impact parasites with minimal host side effects.
John D Chan, Timothy A Day, Jonathan S Marchant   +2 more
doaj   +1 more source