Results 31 to 40 of about 1,521,556 (235)

2-Amino-1,3,4-thiadiazoles as prospective agents in trypanosomiasis and other parasitoses

open access: yesActa Pharmaceutica, 2020
Parasitic diseases are a serious public health problem affecting hundreds of millions of people worldwide. African trypanosomiasis, American trypanosomiasis, leishmaniasis, malaria and toxoplasmosis are the main parasitic infections caused by protozoan ...
Serban Georgeta
doaj   +1 more source

Additional file 3 of Menthol carbonates as potent antiparasitic agents: synthesis and in vitro studies along with computer-aided approaches

open access: yes, 2022
Additional file 3. Menthol carbonates as potent antiparasitic agents: synthesis and in vitro studies along with computer-aided ...
Camila M. Clemente (12869975)   +2 more
core   +1 more source

Anthelmintic resistance in Creole horses in the South of Rio Grande do Sul, Brazil

open access: yesArquivo Brasileiro de Medicina Veterinária e Zootecnia, 2021
The objective of the study was to evaluate the antiparasitic resistance against horse nematodes in the South of Rio Grande do Sul, Brazil. The results concerning the tests of anthelmintic efficacy on horses, stored in the database of the Parasitic ...
J.S. Lignon   +9 more
doaj   +1 more source

In Vitro Primary Screening of a Synthetic Series of Chromenoazoldiones against Trypanosoma cruzi

open access: yesProceedings, 2017
Similarities between parasites and cancer have prompted parasitologists to take advantage of several approaches enabled by cancer research to identify antiparasitic agents [1]. [...]
Cristina Fonseca-Berzal   +4 more
doaj   +1 more source

Facing Diseases Caused by Trypanosomatid Parasites: Rational Design of Pd and Pt Complexes With Bioactive Ligands

open access: yesFrontiers in Chemistry, 2022
Human African Trypanosomiasis (HAT), Chagas disease or American Trypanosomiasis (CD), and leishmaniases are protozoan infections produced by trypanosomatid parasites belonging to the kinetoplastid order and they constitute an urgent global health problem.
Dinorah Gambino, Lucía Otero
doaj   +1 more source

Rationally Designed Minimal Bioactive Domains of AS-48 Bacteriocin Homologs Possess Potent Antileishmanial Properties

open access: yesMicrobiology Spectrum, 2022
Leishmaniasis, a category I neglected tropical disease, is a group of diseases caused by the protozoan parasite Leishmania species with a wide range of clinical manifestations.
Hannah N. Corman   +5 more
doaj   +1 more source

Targeting Metalloenzymes: The “Achilles’ Heel” of Viruses and Parasites

open access: yesPharmaceuticals, 2023
Metalloenzymes are central to the regulation of a wide range of essential viral and parasitic functions, including protein degradation, nucleic acid modification, and many others.
Dimitrios Moianos   +3 more
doaj   +1 more source

Drugs from the Cloudforest: The Search for New Medicines from Monteverde, Costa Rica

open access: yesNatural Product Communications, 2011
The University of Alabama in Huntsville Natural Products Research Group has been investigating the phytopharmaceutical potential of tropical rainforest higher plants from the Monteverde region of northwestern Costa Rica for the past twenty years.
William N. Setzer
doaj   +1 more source

Functional Assessment of 2,177 U.S. and International Drugs Identifies the Quinoline Nitroxoline as a Potent Amoebicidal Agent against the Pathogen Balamuthia mandrillaris

open access: yesmBio, 2018
Balamuthia mandrillaris is a pathogenic free-living amoeba that causes a rare but almost always fatal infection of the central nervous system called granulomatous amoebic encephalitis (GAE). Two distinct forms of B.
Matthew T. Laurie   +9 more
doaj   +1 more source

Analysis of the range of drugs registered in the Russian Federation to control parasitic infections in pigs

open access: yesРоссийский паразитологический журнал, 2023
The purpose of the research is the analysis of the range of antiparasitic drugs for pig breeding as registered in the Russian Federation and included in the State Register of Medicinal Products for Veterinary Use.The control of parasitic diseases is an ...
T. V. Gerunov   +6 more
doaj   +1 more source

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