Overview of Biologically Active Nucleoside Phosphonates
Frontiers in Chemistry, 2021 The use of the phosphonate motif featuring a carbon-phosphorous bond as bioisosteric replacement of the labile P–O bond is widely recognized as an attractive structural concept in different areas of medicinal chemistry, since it addresses the very ...
Elisabetta Groaz, Steven De Jonghe
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Peroxide impact on the fate of veterinary drugs in fertilizers [PDF]
, 2020 The presence of veterinary medicines in organic manure causes soil contamination which contributes to increasing resistance of indigenous microflora to drugs and results in greater susceptibility of people to allergies.
Kalka, Joanna +3 more
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FACTORS LIMITING THE EFFECTIVENESS OF INTESTINAL PARASITOSES’ PHARMACOTHERAPY [PDF]
Journal of IMAB, 2017 The effective etiological antiparasitic treatment fulfils two major goals - to cure the infected patient and to terminate its role as an epidemiologically relevant source of infection.
Kalina Stoyanova +3 more
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Synthesis and Antileishmanial Activity of 1,2,4,5-Tetraoxanes against Leishmania donovani [PDF]
, 2020 A chemically diverse range of novel tetraoxanes was synthesized and evaluated in vitro against intramacrophage amastigote forms of Leishmania donovani. All 15 tested tetraoxanes displayed activity, with IC50 values ranging from 2 to 45 µm.
Amado, Patrícia +5 more
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The Infectious Disease Ontology in the Age of COVID-19 [PDF]
, 2021 The Infectious Disease Ontology (IDO) is a suite of interoperable ontology modules that aims to provide coverage of all aspects of the infectious disease domain, including biomedical research, clinical care, and public health.
Babcock, Shane +3 more
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Peptidyl-prolyl cis-trans isomerases (immunophilins) and their roles in parasite biochemistry, host-parasite interaction and antiparasitic drug action. [PDF]
, 2006 Immunophilin is the collective name given to the cyclophilin and FK506-binding protein (FKBP) families. As the name suggests, these include the major binding proteins of certain immunosuppressive drugs: cyclophilins for the cyclic peptide cyclosporin A ...
Adams +101 more
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2-Amino-1,3,4-thiadiazoles as prospective agents in trypanosomiasis and other parasitoses
Acta Pharmaceutica, 2020 Parasitic diseases are a serious public health problem affecting hundreds of millions of people worldwide. African trypanosomiasis, American trypanosomiasis, leishmaniasis, malaria and toxoplasmosis are the main parasitic infections caused by protozoan ...
Serban Georgeta
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Antiparasitic activity of chicory (Cichorium intybus) and its natural bioactive compounds in livestock: a review [PDF]
, 2018 Increasing drug resistance in gastrointestinal (GI) parasites of livestock and concerns about chemical residues in animal products and the environment are driving the development of alternative control strategies that are less reliant on the use of ...
Boas, Ulrik +7 more
core +4 more sources
Investigating the antiparasitic potential of the marine sesquiterpene avarone, its reduced form avarol, and the novel semisynthetic thiazinoquinone analogue thiazoavarone [PDF]
, 2020 The chemical analysis of the sponge Dysidea avara afforded the known sesquiterpene quinone avarone, along with its reduced form avarol. To further explore the role of the thiazinoquinone scaffold as an antiplasmodial, antileishmanial and antischistosomal
AIELLO, ANNA +13 more
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Anthelmintic resistance in Creole horses in the South of Rio Grande do Sul, Brazil
Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2021 The objective of the study was to evaluate the antiparasitic resistance against horse nematodes in the South of Rio Grande do Sul, Brazil. The results concerning the tests of anthelmintic efficacy on horses, stored in the database of the Parasitic ...
J.S. Lignon +9 more
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