Results 11 to 20 of about 22,070 (144)

Vascular dysfunction in women with recurrent pregnancy loss: Possible association with antiphospholipid antibodies. [PDF]

Int J Gynaecol Obstet
Abstract Objective Antiphospholipid antibodies (aPL) are recognized to have a pivotal role in recurrent pregnancy loss (RPL) and cardiovascular disease. Therefore, we assessed the vascular function of women with RPL and examined the association with each type of aPL.
Yang T, Okada E, Todoroki M, Liu S, Athurupana R, Kataoka K, Kashino C, Mitsui T, Hasegawa T, Kamada Y, Masuyama H, Nakatsuka M.   +11 more
europepmc   +2 more sources

Patient-derived anti-β2GP1 antibodies recognize a peptide motif pattern and not a specific sequence of residues

Haematologica, 2017
Antiphospholipid antibody syndrome is an autoimmune disease characterized by the presence of so-called antiphospholipid antibodies and clinical manifestations such as recurrent thromboembolic or pregnancy complications.
Philippe de Moerloose, Céline Fickentscher, Françoise Boehlen, Jean-Marie Tiercy, Egbert K.O. Kruithof, Karim J. Brandt   +5 more
doaj   +1 more source

The Pathophysiology of The Antiphospholipid Syndrome: A Perspective From The Blood Coagulation System

Clinical and Applied Thrombosis/Hemostasis, 2022
The antiphospholipid syndrome (APS), a systemic autoimmune disease characterized by a hypercoagulability associated to vascular thrombosis and/or obstetric morbidity, is caused by the presence of antiphospholipid antibodies such as lupus anticoagulant ...
R Arreola-Diaz MSc, A Majluf-Cruz MD, PhD, LE Sanchez-Torres PhD, J Hernandez-Juarez PhD   +3 more
doaj   +1 more source

Prevalence and clinical significance of antiphospholipid antibodies among hospitalized COVID-19 patients

Asian Pacific Journal of Tropical Medicine, 2021
Objective: To describe the prevalence of antiphospholipid antibodies in coronavirus disease-19 (COVID-19) and to find potential associations between antiphospholipid antibody positivity and clinical outcomes.
Cesarius Singgih Wahono, Hani Susianti, Tri Wahyudi Iman Dantara, Perdana Aditya Rahman, Mirza Zaka Pratama, Indah Adhita Wulanda, Khoirunisah Dwi Hartanti, Elvira Sari Dewi, Kusworini Handono   +8 more
doaj   +1 more source

Deep capillary retinal ischemia and high-titer prothrombin-associated antiphospholipid antibodies: A case series of three patients

American Journal of Ophthalmology Case Reports, 2019
Purpose: Acute macular neuroretinopathy has been shown to be due to ischemia of the deep capillary retinal plexus and most cases occur in young women; we hypothesized that there may be an association with antiphospholipid antibodies.
Jill R. Schofield, Alan G. Palestine, Victoria Pelak, Marc T. Mathias   +3 more
doaj   +1 more source

Hypermetabolism of basal ganglia in chorea associated with antiphospholipid antibodies demonstrated by F-18 FDG

South African Journal of Radiology, 1997
A brain FDG PET study was performed on a 21-year-old woman with subacute chorea of unknown origin. Associated with her chorea, she had abnormal levels of antiphospholipid antibodies.
M. M. Sathekge, A. Maes, V. Thijst, M. de Roo   +3 more
doaj   +1 more source

The Screening of Antiphospholipid Antibodies in Obstetric Antiphospholipid Syndrome-Like Events: A Regional Perspective

Gynecology Obstetrics & Reproductive Medicine, 2020
Objective: Obstetric antiphospholipid antibody syndrome is clinically recognized by adverse obstetric outcomes. To determine which antibody level best corresponds to the risk of these clinical outcomes is difficult.
Onder Onen, Fusun Gulizar Varol
doaj   +1 more source

Apoptosis, annexin A5 and anti-annexin A5 antibodies in the antiphospholipid syndrome [PDF]

Journal of Medical Biochemistry, 2013
It has been proposed that apoptosis is one of the mechanisms involved in the generation of antiphospholipid antibodies. The presence of antiphospholipid antibodies is the main laboratory criterion for a definite diagnosis of the antiphospholipid syndrome.
Bećarević Mirjana, Ignjatović Svetlana, Majkić-Singh Nada   +2 more
doaj  

Gastrointestinal symptoms as the first manifestation of antiphospholipid syndrome

BMC Gastroenterology, 2021
Background Antiphospholipid syndrome (APS) is an acquired pre-thrombotic autoimmune condition, which produces autoantibodies called antiphospholipid antibodies (APL) against phospholipid-binding plasma proteins. The diagnosis of APS requires at least one
Xiaojuan Zou, Zhongqi Fan, Ling Zhao, Weiling Xu, Jin Zhang, Zhenyu Jiang   +5 more
doaj   +1 more source

Direct-acting oral anticoagulants in antiphospholipid syndrome

Научно-практическая ревматология, 2021
Antiphospholipid syndrome is an acquired autoimmune thrombophilia characterized by the development of recurrent vascular thrombosis of any caliber and type or obstetric pathology and the mandatory identification of persistently positive antiphospholipid ...
T. M. Reshetnyak, K. S. Nurbaeva
doaj   +1 more source