Results 141 to 150 of about 211,280 (349)

Effect of Antiplatelet Therapy on Survival and Organ Support-Free Days in Critically Ill Patients With COVID-19: A Randomized Clinical Trial.

Journal of the American Medical Association (JAMA), 2022
C. Bradbury, P. Lawler, S. Stanworth, B. McVerry, Zoe K. McQuilten, A. Higgins, P. Mouncey, F. Albeidh, K. Rowan, Lindsay R. Berry, E. Lorenzi, R. Zarychanski, Y. Arabi, D. Annane, A. Beane, W. van Bentum-Puijk, Zahra Bhimani, S. Bihari, M. Bonten, F. Brunkhorst, Adrian Buzgau, M. Buxton, M. Carrier, A. Cheng, Matthew E. Cove, M. Detry, L. Estcourt, M. Fitzgerald, T. Girard, E. Goligher, H. Goossens, R. Haniffa, T. Hills, David T. Huang, Christopher M. Horvat, Beverley Hunt, Nao Ichihara, F. Lamontagne, H. Leavis, K. Linstrum, E. Litton, J. Marshall, D. McAuley, A. McGlothlin, S. McGuinness, S. Middeldorp, S. Montgomery, S. Morpeth, S. Murthy, M. Neal, A. Nichol, R. Parke, Jane C. Parker, Luis Reyes, Hiroki Saito, Marlene S. Santos, Christina T. Saunders, A. Serpa-Neto, C. Seymour, M. Shankar-Hari, Vanessa Singh, T. Tolppa, A. Turgeon, Anne M Turner, F. L. van de Veerdonk, Cameron Green, R. J. Lewis, D. Angus, C. McArthur, S. Berry, L. Derde, Steve A. Webb, A. Gordon   +72 more
semanticscholar   +1 more source

Dispensing of actionable pharmacogenetic drugs among adults receiving cardiovascular disease medications in the Northern Netherlands: A serial cross‐sectional study

Clinical Pharmacology &Therapeutics, EarlyView.
The extent of pharmacogenetic (PGx) drug dispensing among Dutch adults receiving medications for cardiovascular disease (CVD) is unknown. Using the University of Groningen IADB.nl pharmacy database, we performed a serial cross‐sectional study (2019–2023) to estimate the annual prevalence of PGx drug dispensing and annual rates of initiation.
Zhuolin Zhang, Guiling Zhou, Jens H. J. Bos, Eelko Hak, Talitha Feenstra, Frank Klont   +5 more
wiley   +1 more source

Urogenital Infection Risk Associated With SGLT2 Inhibitors Versus DPP‐4 Inhibitors in Type 2 Diabetes and Chronic Kidney Disease: A Nationwide Target Trial Emulation

Clinical Pharmacology &Therapeutics, EarlyView.
Although sodium‐glucose cotransporter‐2 inhibitors (SGLT2i) are recommended for patients with type 2 diabetes mellitus (T2DM) and chronic kidney disease (CKD), concerns regarding urogenital infections persist. Therefore, we evaluated the risk of urinary tract infection (UTI) and genital tract infection (GTI) after SGLT2i initiation in this population ...
Young‐Mi Ah, Junsung Nam, Jung Wook Youn, Yun Mi Yu, Soyoung Kang   +4 more
wiley   +1 more source

A functional antiplatelet nanomotor for tri-modal ablation of acute arterial thrombus

Cell Reports Medicine
Summary: Timely and safe thrombolysis is a priority in the clinical management of acute arterial embolism. However, current drug therapies face the challenge of balancing therapeutic benefits with bleeding risks.
Haonan Wu, Hongyuan Zhang, Shuting Guo, Fu Yao, Yuting Sun, Yuan Sun, Shenwu Zhang, Yuequan Wang, Cong Luo   +8 more
doaj   +1 more source

Antiplatelet drugs in cardiological practice: Established strategies and new developments

, 2008
Florian Krötz, Hae-Young Sohn, Volker KlaussCardiology, Medical Policlinic, Ludwig-Maximilians-Universität, Ziemssenstr. 1, 80336 MünchenAbstract: A common pathophysiological course in vascular diseases is an overwhelming activation and ...
Florian Krötz, Volker Klauss, Hae-Young Sohn   +2 more
core  

The in‐hospital administration of sacubitril/valsartan in acute myocardial infarction: A meta‐analysis

ESC Heart Failure, Volume 12, Issue 2, Page 998-1012, April 2025.
In patients with Acute Myocardial Infarction related heart failure, the in‐hospital administration of ARNIs was associated with a reduced risk of MACEs and re‐hospitalizations for heart failure, as well as cardiac remodeling, compared to standard therapy.
Gianluca Di Pietro, Riccardo Improta, Paolo Severino, Andrea D'Amato, Lucia Ilaria Birtolo, Ovidio De Filippo, Antonio Lattanzio, Raffaele De Cristofaro, Giacchino Galardo, Fabrizio D'Ascenzo, Roberto Badagliacca, Gennaro Sardella, Maurizio Volterrani, Francesco Fedele, Carmine Dario Vizza, Massimo Mancone   +15 more
wiley   +1 more source

Antithrombotic therapy for hepatic artery thrombosis following liver transplantation: a case report and literature review

Frontiers in Pharmacology
BackgroundHepatic artery thrombosis (HAT) is one of the most severe complications following liver transplantation (LT). Its prevention requires balancing the risks of bleeding and embolism.
Ziwan Guan, Sha Qiu
doaj   +1 more source

Antiplatelet agents in perioperative noncardiac surgeries: to maintain or to suspend?

, 2018
Juliana Maria Dantas Mendonça Borges,1,2,* Fernanda Oliveira de Carvalho,1,* Isla Alcântara Gomes,3,* Mario Borges Rosa,4,* Antonio Carlos Sobral Sousa1,* 1Nucleus of Post-Graduation in Health Sciences, Federal University of Sergipe, S ...
Borges JMDM, Oliveira de Carvalho F, Sousa ACS, Borges Rosa M, Gomes IA   +4 more
core  

Commonalities of platelet dysfunction in heart failure with preserved ejection fraction and underlying comorbidities

ESC Heart Failure, Volume 12, Issue 2, Page 1013-1028, April 2025.
Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia, Blanche Schroen, Judith M.E.M. Cosemans   +2 more
wiley   +1 more source

Optimal Antithrombotic Therapy for Peripheral Artery Disease: A Systematic Review and Network Meta‐Analysis

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background The optimal antithrombotic regimen for peripheral artery disease, balancing thromboembolic and bleeding risks, remains uncertain. This study aimed to compare the efficacy and safety of antithrombotic regimens in patients with peripheral artery
Yuriko Hiruma, Atsuyuki Watanabe, Tadao Aikawa, Masao Iwagami, Leandro Slipczuk, Jose Wiley, Alexandros Briasoulis, Eric Secemsky, Roger Laham, Toshiki Kuno   +9 more
doaj   +1 more source