Results 291 to 300 of about 211,280 (349)

Clinical pharmacology of antiplatelet drugs

Expert Review of Clinical Pharmacology, 2022
Introduction Platelets play a key role in arterial thrombosis and antiplatelet therapy is pivotal in the treatment of cardiovascular disease. Current antiplatelet drugs target different pathways of platelet activation and show specific pharmacodynamic ...
Georg Gelbenegger, B. Jilma
semanticscholar   +1 more source

Antiplatelet therapy in patients with conservatively managed spontaneous coronary artery dissection from the multicentre DISCO registry.

European Heart Journal, 2021
AIMS The role of antiplatelet therapy in patients with spontaneous coronary artery dissection (SCAD) undergoing initial conservative management is still a matter of debate, with theoretical arguments in favour and against its use.
E. Cerrato, F. Giacobbe, G. Quadri, F. Macaya, M. Bianco, R. Mori, C. Biolè, A. Boi, L. Bettari, C. Rolfo, F. Ferrari, G. Annibali, M. Scappaticci, M. Pavani, U. Barbero, D. Buccheri, C. Cavallino, P. Lombardi, C. Bernelli, F. D’Ascenzo, V. Infantino, A. Gambino, S. Cinconze, A. Rognoni, L. Montagna, I. Porto, G. Musumeci, J. Escaned, F. Varbella   +28 more
semanticscholar   +1 more source

Oral Antiplatelet Therapy After Acute Coronary Syndrome: A Review.

Journal of the American Medical Association (JAMA), 2021
Importance Acute coronary syndrome (ACS) is a major cause of morbidity and mortality in the United States with an annual incidence of approximately 1 million.
Hassan Kamran, H. Jneid, Waleed T. Kayani, S. Virani, G. Levine, Vijay Nambi, U. Khalid   +6 more
semanticscholar   +1 more source

Antiplatelets

Reactions Weekly
Highlights: Introduction Goals of Treatment Antiplatelet Therapy Combination Therapy Monographs ...
Megan Willson, Kimberly C. McKeirnan
  +4 more sources

Antiplatelet therapy

The American Journal of Medicine, 1996
The major clinical indication for antiplatelet therapy has been the prevention of arterial thrombosis. Arterial thrombi are composed of predominantly platelets formed under conditions of elevated shear stress at sites of atherosclerotic vascular injury and disturbed blood flow.
openaire   +2 more sources

Antiplatelet therapy and anticoagulants

The Lancet, 2013
24 www.thelancet.com Vol 382 July 6, 2013 In the WOEST trial, Willem Dewilde and colleagues assess antithrombotic therapy for patients taking oral anticoagulants and receiving a coronary stent. They suggest that for patients undergoing percutaneous coronary intervention and receiving oral anticoagulants and clopidogrel, adding aspirin is harmful.
Axel, Schlitt, Andrea, Rubboli, Kari Eino Juhani, Airaksinen, Gregory Y H, Lip   +3 more
openaire   +4 more sources

Platelet activation and prothrombotic mediators at the nexus of inflammation and atherosclerosis: Potential role of antiplatelet agents.

Blood reviews, 2020
Platelets are central to inflammation-related manifestations of cardiovascular diseases (CVD) such as atherosclerosis. Platelet-activating factor (PAF), thrombin, thromboxane A2 (TxA2), and adenosine diphosphate (ADP) are some of the key agonists of ...
R. Lordan, A. Tsoupras, I. Zabetakis
semanticscholar   +1 more source

Antiplatelet therapy

Hospital Medicine, 2000
Within the last few years antiplatelet therapy has developed exponentially, with new agents being tested in an increasing number of clinical scenarios. The mechanism of action of these newer agents and evidence of benefit is prevented in this review.
openaire   +2 more sources

Antiplatelet effect of demethyldiisoeugenol

Canadian Journal of Physiology and Pharmacology, 1996
A semisynthetic chemical compound, demethyldiisoeugenol, concentration dependently inhibited platelet aggregation and ATP release stimulated by thrombin (0.1 U/mL), platelet-activating factor (2 ng/mL), arachidonic acid (100 microM), collagen (10 micrograms/mL), and U46619 (1 microM) in rabbit washed platelets.
C H, Liao, F N, Ko, Y H, Kuo, C M, Teng
openaire   +2 more sources

Antiplatelet therapy in children

Thrombosis Research, 2006
Platelets are essential for the maintenance of vascular integrity and control of bleeding at sites of injury, but they are also implicated in the progression of atherosclerotic lesions and arterial vascular thrombosis. The use of antiplatelet drugs for the primary and secondary prevention of cardiovascular and cerebrovascular thromboses in adult ...
Israels, Sara J., Michelson, Alan D.
openaire   +3 more sources