Results 221 to 230 of about 109,169 (264)

Antiplatelet Therapy

Platelets are a crucial component in the maintenance of normal haemostasis. In response to vascular damage, activated platelets adhere to the damaged endothelium leading to both aggregation and coagulation. Under healthy conditions, these processes prevent excessive vascular haemorrhage and promote vascular repair and regeneration.
Richard T, Amison, Simon C, Pitchford
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Antiplatelet therapy and exodontia

The Journal of the American Dental Association, 2015
This is a review of the management considerations regarding exodontia for patients taking antithrombotic medications that affect platelet function or aggregation.The authors reviewed the literature, focusing on the indications and mechanisms of antiplatelet therapy and the perioperative management of patients taking these agents who require exodontia ...
Willem H, Schreuder, Zachary S, Peacock
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Antiplatelet Therapy in Diabetes

Endocrinology and Metabolism Clinics of North America, 2018
Cardiovascular disease (CVD) is a significant cause of morbidity and mortality among patients with diabetes mellitus (DM). Increased platelet reactivity among patients with DM contributes to disproportionately high levels of atherothrombotic CVD. Consequently, there has been tremendous interest in exploring the role of antiplatelet therapies in DM to ...
Arjun, Majithia, Deepak L, Bhatt
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Antiplatelet therapy and anticoagulants

The Lancet, 2013
24 www.thelancet.com Vol 382 July 6, 2013 In the WOEST trial, Willem Dewilde and colleagues assess antithrombotic therapy for patients taking oral anticoagulants and receiving a coronary stent. They suggest that for patients undergoing percutaneous coronary intervention and receiving oral anticoagulants and clopidogrel, adding aspirin is harmful.
Bartosz, Hudzik, Andrzej, Lekston, Lech, Polonski   +2 more
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Aspirin as an Antiplatelet Agent

Archives of Internal Medicine, 1980
To the Editor. —There have been many studies relating the effect of aspirin prophylaxis on thromboembolisms. 1,2 Evaluation of the clinical data presented in them indicates that thromboembolic disease developed more rarely in men than in women under the identical dosage of aspirin given for prophylaxis against thromboembolism after hip surgery and ...
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Antiplatelet effect of demethyldiisoeugenol

Canadian Journal of Physiology and Pharmacology, 1996
A semisynthetic chemical compound, demethyldiisoeugenol, concentration dependently inhibited platelet aggregation and ATP release stimulated by thrombin (0.1 U/mL), platelet-activating factor (2 ng/mL), arachidonic acid (100 microM), collagen (10 micrograms/mL), and U46619 (1 microM) in rabbit washed platelets.
C H, Liao, F N, Ko, Y H, Kuo, C M, Teng
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Novel Antiplatelet Therapies

Current Atherosclerosis Reports, 2011
Advances in antiplatelet therapy have significantly improved outcomes in patients with ischemic heart disease. Thienopyridines remain a cornerstone of therapy along with aspirin. Recently, concerns have been raised about the use of clopidogrel due to its pharmacokinetic and pharmacogenetic interpatient variability.
Luke, Kim, Konstantinos, Charitakis, Rajesh V, Swaminathan, Dmitriy N, Feldman   +3 more
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Antiplatelet therapy in cardiology

Clinical Medicine (Russian Journal), 2016
Platelets are important components of hemostasis and play a key role in the formation of atherothrombosis. Rupture or erosion of atherosclerotic plaque gives rise to a thrombus with the involvement of platelets. Antiplatelet agents are instrumental in preventing the development of atherothrombosis of different localization, including coronary arteries.
L V, Popova, M B, Aksenova, T V, Khlevchuk   +2 more
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Antiplatelet and antithrombin therapy

Coronary Artery Disease, 1994
The contemporary pharmacologic treatment of acute myocardial infarction (AMI) includes reperfusion via a thrombolytic agent as well as adjunctive therapy with aspirin and heparin (1). Despite the advances made, current management is limited by the fact that infarct-related artery patency is achieved in only 60–80% of patients at 90 min and Thrombolysis
A, Fernández-Ortiz, I K, Jang, V, Fuster   +2 more
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Evaluation of an antiplatelet globulin

Thrombosis Research, 1979
Abstract Dog antiplatelet serum was produced by immunization of rabbits with repeatedly washed and gel-filtrated platelets. After decomplementation and absorption with dog red cells, the IgG fraction of the antiserum was isolated by precipitation with Rivanol and ammonium sulphate.
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