Results 51 to 60 of about 256,425 (387)

European Stroke Organisation expedited recommendation for the use of short-term dual antiplatelet therapy early after minor stroke and high-risk TIA

European Stroke Journal, 2021
Prevention of early recurrent ischaemic stroke remains a priority in people with TIA or ischaemic stroke. A number of trials have recently been completed assessing the efficacy of short-term dual antiplatelet therapy (DAPT) versus single antiplatelet ...
J. Dawson, Á. Merwick, A. Webb, M. Dennis, J. Ferrari, Ana Catarina Fonseca   +5 more
semanticscholar   +1 more source

Thromboprophylaxis in atrial fibrillation and association with cognitive decline: systematic review [PDF]

, 2016
Objective:Atrial Fibrillation (AF) is associated with dementia. If AF-related cognitive decline is driven by cerebral embolic events, thromboprophylaxis may impact on this.
Lane, Deirdre A., Moffitt, Peter, O'Connell, Janice, Park, Helen, Quinn, Terence J.   +4 more
core   +2 more sources

Correlation between prescribing quality and pharmaceutical costs in English primary care: national cross-sectional analysis [PDF]

, 2011
Background Both pharmaceutical costs and quality-indicator performance vary substantially between general practices, but little is known about the relationship between prescribing costs and quality Aim To measure the association between prescribing ...
Allsup, Amanda Howe, Fisher, Fleetcroft, Fleetcroft, Nicholas Steel, Richard Cookson, Robert Fleetcroft, Walker   +8 more
core   +1 more source

Current and Novel Antiplatelet Therapies for the Treatment of Cardiovascular Diseases

International Journal of Molecular Sciences, 2021
Over the last decades, antiplatelet agents, mainly aspirin and P2Y12 receptor antagonists, have significantly reduced morbidity and mortality associated with arterial thrombosis.
Georges Jourdi, M. Lordkipanidzé, A. Philippe, C. Bachelot-Loza, P. Gaussem   +4 more
semanticscholar   +1 more source

Antiplatelet and Antithrombotic Activities of Non-Steroidal Anti-Inflammatory Drugs Containing an N-Acyl Hydrazone Subunit

Molecules, 2014
Nonsteroidal anti-inflammatory drugs (NSAIDs) 1–5 containing an N-acyl hydrazone subunit were prepared and their antiplatelet and antithrombotic activities assessed in vitro and in vivo.
Rafael Consolin Chelucci, Luiz Antônio Dutra, Maria Elisa Lopes Pires, Thais Regina Ferreira de Melo, Priscila Longhin Bosquesi, Man Chin Chung, Jean Leandro dos Santos   +6 more
doaj   +1 more source

Antioxidant Properties of Oral Antithrombotic Therapies in Atherosclerotic Disease and Atrial Fibrillation

Antioxidants, 2023
The thrombosis-related diseases are one of the leading causes of illness and death in the general population, and despite significant improvements in long-term survival due to remarkable advances in pharmacologic therapy, they continue to pose a ...
Luigi Falco, Viviana Tessitore, Giovanni Ciccarelli, Marco Malvezzi, Antonello D’Andrea, Egidio Imbalzano, Paolo Golino, Vincenzo Russo   +7 more
doaj   +1 more source

Is clopidogrel better than aspirin following breakthrough strokes while on aspirin? A retrospective cohort study. [PDF]

, 2014
ObjectiveThere is insufficient evidence on which to base a recommendation for optimal antiplatelet therapy following a stroke while on aspirin. The objective was to compare clopidogrel initiation vs aspirin reinitiation for vascular risk reduction among ...
Chang, Ku-Chou, Lee, Hsuei-Chen, Lee, Jiann-Der, Lee, Meng, Lee, Tsong-Hai, Ovbiagele, Bruce, Rao, Neal M, Saver, Jeffrey L, Wang, Hui-Hsuan, Wu, Chih-Ying, Wu, Yi-Ling   +10 more
core   +1 more source

Association of Antiplatelet Therapy, Including Cilostazol, With Improved Survival in Patients With Moyamoya Disease in a Nationwide Study

Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2021
Background Although antiplatelet agents are frequently prescribed in moyamoya disease in routine clinical practice, there are no large‐scale epidemiologic trials or randomized trial evidence to support their use in patients with moyamoya disease. Methods
W. Seo, Jaeyoung Kim, Eun‐Hyeok Choi, Yesel Kim, Jong-Won Chung, J. Saver, O. Bang, Gyeong-Moon Kim   +7 more
semanticscholar   +1 more source

The Multifaceted Effects of Non-Steroidal and Non-Opioid Anti-Inflammatory and Analgesic Drugs on Platelets: Current Knowledge, Limitations, and Future Perspectives

Pharmaceuticals
Non-steroidal anti-inflammatory drugs (NSAIDs) are among the most widely utilized pharmaceuticals worldwide. Besides their recognized anti-inflammatory effects, these drugs exhibit various other pleiotropic effects in several cells, including platelets ...
Alexandros Tsoupras, Despina A. Gkika, Ilias Siadimas, Ioannis Christodoulopoulos, Pavlos Efthymiopoulos, George Z. Kyzas   +5 more
doaj   +1 more source

Effects of clopidogrel and prednisone on platelet function in healthy dogs

Journal of Veterinary Internal Medicine, 2020
Background Glucocorticoids cause hypercoagulability, but it is unknown if they counteract clopidogrel's antiplatelet effects. Hypothesis/Objectives Determine the effects of clopidogrel and prednisone on platelet function. Animals Twenty‐four healthy dogs.
John Thomason, Allison P. Mooney, Joshua M. Price, Jacqueline C. Whittemore   +3 more
doaj   +1 more source