Results 201 to 210 of about 211,280 (349)

Predicting Device‐Induced Platelet Damage in Assisted Circulation Using a New Biophysical Model and Experimental Validation

open access: yesArtificial Organs, EarlyView.
Quantitative assessment of a newly proposed CFD‐based biophysical model for predicting device‐induced platelet damage by circulatory assist devices was performed. The new model preserved the relative trends observed previously with the power‐law formulation across a range of clinically relevant pump operating conditions, while demonstrating improved ...
Anik Tarafder   +3 more
wiley   +1 more source

Clinical Outcomes After Percutaneous Coronary Intervention in Patients With Cirrhosis: A Multicentre National Study

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
Summary of a multicentre TriNetX study evaluating outcomes after percutaneous coronary intervention (PCI) in patients with cirrhosis. Cirrhosis was associated with higher 1‐year gastrointestinal bleeding and mortality, especially with decompensated disease.
Dhir Gala   +13 more
wiley   +1 more source

Safety of Nonsteroidal Anti-Inflammatory Drug Use in Traumatic Brain Injury. [PDF]

open access: yesPharmacotherapy
Beavers J   +10 more
europepmc   +1 more source

Impact of operative time on complications after PCNL in the elderly (aged ≥70 years): the Safety and Efficacy of Nephrolithotomy in Older patients undergoing PCNL (SENIOR‐PCNL) study

open access: yesBJU International, EarlyView.
Objectives To evaluate the association between operative time (OT) and postoperative complications after percutaneous nephrolithotomy (PCNL) in elderly patients, and to identify a clinically meaningful OT threshold for risk stratification. Patients and Methods A retrospective international multicentre study was performed including patients aged ≥70 ...
Łukasz Nowak   +41 more
wiley   +1 more source

Ischaemic stroke and 5‐fluorouracil or capecitabine: A systematic review and meta‐analysis of harms and a retrospective study of the WHO pharmacovigilance database

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Aim Fluoropyrimidines, including 5‐fluorouracil (5‐FU) and capecitabine, are cornerstone antineoplastic agents for cancer. Case reports suggest that these drugs may be associated with an under‐recognised risk of ischaemic stroke or transient ischaemic attack (TIA).
Sophie Nguyen   +12 more
wiley   +1 more source

Bruton tyrosine kinase inhibitors and cardiovascular adverse events

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Bruton tyrosine kinase inhibitors (BTKi) have transformed the management of chronic lymphocytic leukaemia and other B‐cell malignancies, yet their therapeutic benefit is tempered by clinically relevant cardiovascular toxicities (predominantly atrial fibrillation, hypertension, bleeding and ventricular arrhythmias).
Massimiliano Camilli   +4 more
wiley   +1 more source

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