The machine learning methods to analyze the using strategy of antiplatelet drugs in ischaemic stroke patients with gastrointestinal haemorrhage [PDF]
Background For ischaemic stroke patients with gastrointestinal haemorrhage, stopping antiplatelet drugs or reducing the dose of antiplatelet drugs was a conventional clinical therapy method. But not a study to prove which way was better.
Chaohua Cui +4 more
doaj +2 more sources
The Impact of Preinjury Use of Antiplatelet Drugs on Outcomes of Traumatic Brain Injury: A Systematic Review and Meta-Analysis [PDF]
ObjectiveThe study aimed to compare outcomes of traumatic brain injury (TBI) in patients on pre-injury antiplatelet drugs vs. those, not on any antiplatelet or anticoagulant drugs.MethodsPubMed, Embase, and Google Scholar databases were searched up to ...
Li Cheng, Gaoliang Cui, Rong Yang
doaj +2 more sources
Pharmacogenetics of Antiplatelet Drugs [PDF]
Pharmacogenetics refers to the genetic factors that influence the response to a drug, often involving genetic variations in drug metabolizing enzymes. The pharmacogenetics of antiplatelet agents is in its infancy and largely reflects variations in drug ...
Ronan Curtin, Desmond J. Fitzgerald
doaj +3 more sources
Efficacy and safety of new oral anticoagulants combined with antiplatelet drugs in the treatment of coronary heart disease: Systematic evaluation and meta‐analysis [PDF]
Objective To analyze the efficacy and safety of antiplatelet drugs combined with new oral anticoagulants (noac) in the treatment of coronary atherosclerotic heart disease (CAD).
Alimila Saiyitijiang +3 more
doaj +2 more sources
High-throughput combinatorial screening of antiplatelet drugs for personalized medicine [PDF]
Cardiovascular disease (CVD) remains the leading cause of death worldwide. Platelet activation plays a critical role in arterial thrombotic events such as myocardial infarction. Although antiplatelet drugs are standard therapies, they are associated with
Chenguang Wang +9 more
doaj +2 more sources
Influence of antiplatelet drugs on gastric ulcer healing after endoscopic submucosal dissection in patients with early gastric cancer [PDF]
Objectives The causes of drug‐induced gastroduodenal injuries primarily include antithrombotic drugs, including low‐dose aspirin, non‐steroidal anti‐inflammatory drugs, and corticosteroids.
Kazuto Takahashi +10 more
doaj +2 more sources
Antiplatelet drugs and liver fibrosis
Liver fibrosis results from an imbalance between extracellular matrix formation and degradation. The background of liver fibrosis is chronic inflammation and subsequent microcirculation disturbance including microthrombosis.
Pamela Czajka +7 more
doaj +3 more sources
British Journal of Pharmacology (2006) 147, S241–S251.
Gustav, Born, Carlo, Patrono
+6 more sources
SummaryPlatelets play a major role in thromboembolic diseases, and so antiplatelet therapy remains crucial in treatment and prophylaxis. Upon vascular injury, platelets rapidly adhere to the exposed subendothelial matrix, after which they become activated, resulting in the recruitment of additional platelets from the circulation to eventually form a ...
Simon F, De Meyer +4 more
+5 more sources
Antiplatelet drug interactions [PDF]
Abstract. Mackenzie IS, Coughtrie MWH, MacDonald TM, Wei L. (Medicines Monitoring Unit (MEMO); and Centre for Oncology & Molecular Medicine, Division of Medical Sciences, University of Dundee, Ninewells Hospital & Medical School; Dundee, UK). Antiplatelet drug interactions (Review‐Symposium).
Mackenzie, I. S. +3 more
openaire +3 more sources

