Results 161 to 170 of about 139,370 (300)
ABSTRACT Background Polycythemia vera (PV) and essential thrombocythemia (ET) are associated with a well‐recognized increased risk of thrombotic events, bleeding, and all‐cause mortality, but the frequency of these outcomes during treatment has rarely been assessed in large cohorts.
Anneli Enblom Larsson +5 more
wiley +1 more source
Spinal Subdural Hematoma After Dual Antiplatelet Therapy. [PDF]
Prakash N +9 more
europepmc +1 more source
ABSTRACT Introduction Novel targeted agents have transformed the treatment of chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), including continuous BTK inhibitor (BTKi) therapy and time‐limited regimens such as venetoclax‐obinutuzumab (Ven‐O) and ibrutinib‐venetoclax (I + V).
Rebecca Tidswell +7 more
wiley +1 more source
Antiplatelet therapy trends in Chinese ischemic stroke patients 2019-2024. [PDF]
Wu M, Jiang H, Sun A, Zhu B, Zhao Z.
europepmc +1 more source
Acalabrutinib in Chronic Lymphocytic Leukemia: Pharmacology and Emerging Clinical Perspectives
ABSTRACT Acalabrutinib, a second‐generation Bruton's tyrosine kinase inhibitor (BTKi), is characterized by enhanced specificity and selectivity for BTK with minimal off‐target effects, offering a significant evolution in the treatment of chronic lymphocytic leukemia (CLL). Its mechanism of action, a covalent binding to Cys481 within the BTK active site,
Gianluca Gaidano, Romano Danesi
wiley +1 more source
CYP2C19 Genotype-Guided Antiplatelet Therapy in Precision Medicine for Stroke. [PDF]
Zhang Q, Liu T.
europepmc +1 more source
ABSTRACT Background Inherited platelet disorders (IPDs) are rare hematologic conditions encompassing a heterogeneous spectrum of quantitative and qualitative platelet defects, frequently associated with variable clinical phenotypes and comorbidities. Accurate diagnosis necessitates comprehensive genetic characterization, detailed clinical and bleeding ...
Silvia Ferrari +6 more
wiley +1 more source
Impact of antiplatelet therapy on the hemostatic efficacy of platelet-targeted FVIII gene therapy in hemophilia A mice. [PDF]
Yu H +4 more
europepmc +1 more source
ABSTRACT Background Data on adverse events in patients developing atrial fibrillation (AF) after cardiac arrest (CA) are limited. Methods Retrospective analysis using the TriNetX network. Adults (≥ 18 years) with CA (ICD‐10‐CM I46) from 2014 to 2024 were divided into two cohorts: those with new‐onset AF (I48) within 2 days after CA and those without ...
Enrico Tartaglia +10 more
wiley +1 more source

