Results 41 to 50 of about 2,461,363 (302)

Effects of Add‐On Icosapent Ethyl With Standard Treatment on Functional Outcomes and Inflammatory Biomarkers in Acute Ischemic Stroke: A Blinded Randomized Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand, Seyed Hossein Aghamiri, Saeed Mohmammad Soleymani, Shadiyeh Bararpoor Poshkohi, Samaneh Masoudi, Hadi Esmaily   +5 more
wiley   +1 more source

Advancing Stroke Clinical Trials Using Community Engagement and Implementation Science Approaches

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Stroke clinical trials are essential for advancing stroke care but can face challenges with recruitment, retention, clinical relevance, and translation into real‐world practice. We propose that integrating community engagement and implementation science approaches into stroke trials can help address these needs.
Lesli E. Skolarus, Devin L. Brown, Bernadette Boden‐Albala   +2 more
wiley   +1 more source

Bleeding complications related to external ventricular drainage placement in patients with ruptured intracranial aneurysms: a single-center study

Frontiers in Surgery
ObjectiveAcute aneurysmal rupture can be treated with endovascular therapy or surgical clipping. For patients with concurrent acute hydrocephalus, the placement of an external ventricular drainage (EVD) is required.
Yue Tang, Xiangping Zhong, Tingting Lin, Fujun Zuo, Min Fu, Li Wang, Xiaodu Yu, Dong Liu, Jincan Zhang   +8 more
doaj   +1 more source

Modern Management of Asymptomatic Carotid Stenosis: A Meta‐Analysis of CREST‐2, SPACE‐2, and ECST‐2

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Recent randomized trials (CREST‐2, SPACE‐2, and ECST‐2) have compared carotid revascularization (carotid endarterectomy [CEA] or carotid artery stenting [CAS]) plus contemporary medical therapy (CMT) versus CMT alone in asymptomatic carotid stenosis.
Aasim Ali, Waqar Ahmed Cheema, Fiza Nisar, Muhammad Shamoon, Sameen Sarfaraz, Ahmad Butt, Muhammad Abdullah Ali, Armaghana Abdullah, Muhammad Asad Shabbir, Muhammad Talha, Hammad Azam, Aimen Anwaar Pannun, Usama Saleem, Anousha Tanveer, Mukesh Sharma   +14 more
wiley   +1 more source

Five-year trends in antiretroviral usage and drug costs in HIV-infected children in Thailand. [PDF]

, 2013
BACKGROUND: As antiretroviral treatment (ART) programs mature, data on drug utilization and costs are needed to assess durability of treatments and inform program planning.
Lallemant, Marc, Jourdain, G, Layangool, P, Ngampiyaskul, Chaiwat, Collins, Intira, Na-Rajsima, S., Collins, I., Collins, I, Jourdain, Gonzague, Wanchaitanawong, Vanichaya, Wanchaitanawong, V, Collins, Intira Jeannie, Ngampiyasakul, Chaiwat, Borkird, Thitiporn, Pagdi, Karin, Wanchaitanawong, V., Cairns, J, Cairns, J., Cairns, John, Pagdi, K., Ngampiyaskul, C, Lallemant, M, Layangool, P., Le Coeur, Sophie, Na-Rajsima, Sathaporn, Layangool, Prapaisri, Ngampiyaskul, C., Borkird, T., Na-Rajsima, S, Pagdi, K, Borkird, T, Le Coeur, S   +31 more
core   +1 more source

Diffuse MRI Edema Predicts Relapse in Cerebral Amyloid Angiopathy–Related Inflammation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To identify MRI predictors of relapse and quantify relapse and mortality risk in cerebral amyloid angiopathy–related inflammation (CAA‐RI). A secondary objective was to assess the association between mycophenolate mofetil use and relapse risk. Methods We performed a retrospective cohort study of 36 patients with CAA‐RI treated at the
G. Abbas Kharal, Gowtham Yerneni, Kim J. Griffin, Nicolas Thompson, Ken Uchino, Irene Katzan, Dolora Wisco, Abeer Farrag, Jayashree Sundarajan, Andrew Russman, M. Shazam Hussain   +10 more
wiley   +1 more source

Cerebral DWI lesion burden following carotid artery stenting with guided antiplatelet therapy: a retrospective comparative study

CVIR Endovascular
Purpose To analyze the number, location, and clinical significance of new ischemic lesions (NIL) after carotid stenting in patients with guided antiplatelet therapy.
Pavol Vigláš, Jan Raupach, Aleš Hejčl, David Černík, Karel Hrach, Patrik Matras, Pavla Bradáčová, Pavel Ryška, Filip Cihlář   +8 more
doaj   +1 more source

GENETICS OF CLOPIDOGREL RESISTANCE: RECENT DATA

Российский кардиологический журнал, 2015
Antiplatelet therapy is one of the most importance in therapy of patients with injured coronary, cerebral and peripheral arteries. The standard of acute coronary syndrome patients treatment is double antiplatelet therapy: acetylsalicylic acid with ...
K. B. Mirzaev, D. A. Sychev, D. A. Andreev   +2 more
doaj   +1 more source

Should duration of dual antiplatelet therapy depend on the type and/or potency of implanted stent? A pre-specified analysis from the PROlonging Dual antiplatelet treatment after Grading stent-induced Intimal hyperplasia studY (PRODIGY)

, 2013
The purpose of this pre-specified analysis of the PROlonging Dual antiplatelet treatment after Grading stent-induced Intimal hyperplasia studY (PRODIGY) was to assess device-specific outcomes relative to different duration of dual antiplatelet therapy ...
TEBALDI, Matteo, Marco Valgimigli, Pascal Vranckx, for the PROlonging Dual antiplatelet treatment after Grading stent induced Intimal hyperplasia studY Investigators, BORGHESI, Marco, FERRARI, Roberto, Giovanni Parrinello   +6 more
core   +1 more source

Assessing the Sensitivity and the Clinical Impact of the 2023 American College of Rheumatology/EULAR Classification Criteria in Obstetric Antiphospholid Syndrome: Findings From a Multicenter Italian Cohort With a Long‐Term Follow‐Up

Arthritis Care &Research, EarlyView.
Objective The aim of this study was to evaluate the sensitivity of the 2023 American College of Rheumatology (ACR)/EULAR classification criteria for antiphospholipid syndrome (APS) in a real‐world cohort of women diagnosed with primary obstetric APS (oAPS) and to assess their ability to identify patients at risk of future pregnancy complications ...
Francesca Ruffilli, Cecilia Nalli, Francesca Crisafulli, Carlo Garaffoni, Marcello Govoni, Giulia Voltarel, Alba C. Pozzi, Beatrice Maranini, Ettore Silvagni, Alessandra Bortoluzzi, Angela Tincani   +10 more
wiley   +1 more source