Results 51 to 60 of about 101,135 (306)

Dual Antiplatelet Therapy (DAPT) versus No Antiplatelet Therapy and Incidence of Major Bleeding in Patients on Venoarterial Extracorporeal Membrane Oxygenation. [PDF]

open access: yesPLoS ONE, 2016
Bleeding is a frequent complication in patients on venoarterial extracorporeal membrane oxygenation (VA-ECMO). An indication for dual antiplatelet therapy due to coronary stent implantation is present in a considerable number of these patients.
Dawid L Staudacher   +5 more
doaj   +1 more source

Safety of Prescription Nonsteroidal Anti‐inflammatory Drugs in Adults With Inflammatory Bowel Disease: Data From a Large Administrative Claims Cohort

open access: yesArthritis Care &Research, EarlyView.
Objective The concern that nonsteroidal anti‐inflammatory drugs (NSAIDs) may precipitate flares of inflammatory bowel disease (IBD) has limited their use in managing musculoskeletal symptoms in those with IBD, but safety data are mixed. Methods This retrospective cohort study included patients with IBD aged at least 18 years from Optum's deidentified ...
Adam S. Mayer   +4 more
wiley   +1 more source

Benefits and risks of resumption of antiplatelet therapy in patients after intracranial hemorrhage: a Meta-analysis

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery, 2018
Objective To assess the benefits and risks of resumption of antiplatelet therapy in patients after intracranial hemorrhage (ICH) by Meta-analysis. Methods Retrieve relevant case-control studies or cohort studies from online databases (January 1, 1990 ...
Qian LI   +8 more
doaj   +1 more source

Adherence to Antiplatelet Therapy after Coronary Intervention among Patients with Myocardial Infarction Attending Vietnam National Heart Institute

open access: yes, 2019
Adherence to antiplatelet therapy is critical to successful treatment of cardiovascular conditions. However, little has been known about this issue in the context of constrained resources such as in Vietnam. The objective of this study was to examine the
Thi, Thu Ha Nguyen   +3 more
core   +1 more source

Antiplatelet therapy versus observation in low-risk essential thrombocythemia with CALR mutation [PDF]

open access: yes, 2016
The role of antiplatelet therapy as primary prophylaxis of thrombosis in low-risk essential thrombocythemia has not been studied in randomized clinical trials.
Chiara Paoli   +64 more
core   +1 more source

Selective Inhibition of Integrin β3 Topology Provides a Safer Antithrombotic Strategy

open access: yesAdvanced Science, EarlyView.
Current integrin αIIbβ3 inhibitors effectively reduce thrombosis but also increase bleeding risk. During thrombosis, high shear blood flow can directly activate the integrin αIIbβ3 via a distinct topological change in the β3 transmembrane domain, independent of hemostatic platelet signaling.
Joonha Lee   +11 more
wiley   +1 more source

Clinical presentations, antiplatelet strategies and prognosis of patients with stent thrombosis: an observational study of 140 patients. [PDF]

open access: yesPLoS ONE, 2012
BACKGROUND: Until now there has been scarce evidence regarding an optimal antiplatelet strategy and clinical outcomes for patients who had suffered from stent thrombosis (ST).
Ya-Ling Han   +12 more
doaj   +1 more source

FGL2‐HDAC11 Drives Immunothrombosis via NETs‐Mediated Endothelial Capillarization in MASLD Fibrosis

open access: yesAdvanced Science, EarlyView.
ABSTRACT Metabolic dysfunction–associated steatotic liver disease (MASLD) is frequently accompanied by hepatic fibrosis and systemic cardiovascular complications; however, the mechanistic interplay between coagulation abnormalities and disease progression remains poorly defined.
Xitang Li   +16 more
wiley   +1 more source

Safety of lumbar puncture in patients on antiplatelet therapy: A real-world study assessing red blood cell counts in cerebrospinal fluid

open access: yesJournal of International Medical Research
Objective Elevated cerebrospinal fluid red blood cell counts in patients on antiplatelet therapy during lumbar puncture raise concerns about increased bleeding risk.
Qiwei Ran   +3 more
doaj   +1 more source

Oral Anticoagulant and Antiplatelet Therapy for Peripheral Arterial Disease: A Meta-analysis of Randomized Controlled Trials

open access: yesClinical and Applied Thrombosis/Hemostasis, 2021
Peripheral artery disease (PAD) is a common disease affecting over 200 million people worldwide. PAD is associated with significant limb and cardiovascular morbidity and mortality which is reduced by antiplatelet and antithrombotic therapy.
Tao Tang PhD   +6 more
doaj   +1 more source

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