Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2001 Na(+)/H(+) antiporters are membrane proteins that play a major role in pH and Na(+) homeostasis of cells throughout the biological kingdom, from bacteria to humans and higher plants. The emerging genomic sequence projects already have started to reveal that the Na(+)/H(+) antiporters cluster in several families.
Padan , E. +3 more
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A Kick-Start for CLC Antiporters’ Pharmacology [PDF]
Chemistry & Biology, 2012 Despite the role of chloride channels and anion/proton antiporters of the CLC protein family in physiological processes and different genetic diseases, their pharmacology has been under-developed. In this issue of Chemistry & Biology, Howery et al. report the synthesis of 4'-octanamidostilbene-2,2'-disulfonate, the first high-affinity inhibitor of a ...
Zifarelli G, Pusch M
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Functional comparison of plasma-membrane Na+/H+ antiporters from two pathogenic
BMC Microbiology, 2008 Background The virulence of Candida species depends on many environmental conditions. Extracellular pH and concentration of alkali metal cations belong among important factors.
Sychrova Hana, Krauke Yannick
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SLC37A1 and SLC37A2 are phosphate-linked, glucose-6-phosphate antiporters. [PDF]
PLoS ONE, 2011 Blood glucose homeostasis between meals depends upon production of glucose within the endoplasmic reticulum (ER) of the liver and kidney by hydrolysis of glucose-6-phosphate (G6P) into glucose and phosphate (P(i)).
Chi-Jiunn Pan +5 more
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Function and Regulation of Acid Resistance Antiporters
The Journal of Membrane Biology, 2019 Bacterial pathogens are a major cause of foodborne diseases and food poisoning. To cope with the acid conditions encountered in different environments such as in fermented food or in the gastric compartment, neutralophilic bacteria have developed several adaptive mechanisms.
Eva-Maria Krammer, Martine Prévost
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Theoretical study of active secondary transport: Unexpected differences in molecular mechanisms for antiporters and symporters [PDF]
, 2022 Successful functioning of biological cells relies on efficient translocation of different materials across cellular membranes. An important part of this transportation system is membrane channels that are known as antiporters and symporters. They exploit
Anatoly B. Kolomeisky +3 more
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Effect of preparations Methyure and Ivine on Са(2+)-ATPases activity in plasma and vacuolar membrane of corn seedling roots under salt stress conditions [PDF]
The Ukrainian Biochemical Journal, 2017 Ca2+-ATPases regulate the functioning of Ca2+-dependent signaling pathway SOS which provides removal of Na+ from the cytoplasm of cells via Na+/H+-antiporters in saline conditions.
M. V. Rudnytska, T. A. Palladina
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Molecular characterization of the Na+/H+-antiporter NhaA from Salmonella Typhimurium. [PDF]
PLoS ONE, 2014 Na+/H+ antiporters are integral membrane proteins that are present in almost every cell and in every kingdom of life. They are essential for the regulation of intracellular pH-value, Na+-concentration and cell volume.
Christopher J Lentes +5 more
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Are Amino Acid Antiporters Biological Maxwell Demons?
, 2023 Amino acid antiporters mediate the 1:1 exchange of groups of amino acids. Whether substrate specificity can be different for the inward and outward facing conformation has not been investigated systematically, although examples of asymmetric transport ...
Bröer, S (via Mendeley Data)
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Molecular Mechanisms of Active Transport in Antiporters: Kinetic Constraints and Efficiency
, 2021 A vital role in supporting successful functioning of biological cells is played by membrane channels called antiporters. These channel proteins utilize the concentration gradient of one type of species to move another type of species in the opposite ...
Kolomeisky, Anatoly B., Berlaga, Alex
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