Results 71 to 80 of about 8,789 (241)

Mrp Antiporters Have Important Roles in Diverse Bacteria and Archaea

Frontiers in Microbiology, 2017
Mrp (Multiple resistance and pH) antiporter was identified as a gene complementing an alkaline-sensitive mutant strain of alkaliphilic Bacillus halodurans C-125 in 1990.
Masahiro Ito, Masahiro Ito, Masato Morino, Masato Morino, Terry A. Krulwich   +4 more
doaj   +1 more source

Ursolic Acid Alleviates Orchitis via Modulating Ferroptosis in Peritubular Myoid Cells of Testis

Animal Research and One Health, EarlyView.
Ursolic acid modulates key ferroptosis‐related pathways in the peritubular myoid cells of the testis in forest musk deer. ABSTRACT Chronic stress adversely affects reproductive health, increasing susceptibility to pathologies such as orchitis. Additionally, the maintenance of iron homeostasis is essential for preserving the function of the testicles ...
Yang Wang, Tianqi Jin, Zexin Chen, Ye Gong, Qimin Liu, Zifang Wu, Heran Cao, Yan Li, Yuyan Liu, Tianhao Yang, Zhihong Jiang, Wuzi Dong   +11 more
wiley   +1 more source

Two Vitis vinifera MATE proteins act as tonoplast acylated anthocyanin / H+ antiporters

, 2008
Two Vitis vinifera MATE proteins act as tonoplast acylated anthocyanin / H+ antiporters. 8.
Gomez, Camila, Torregrosa, Laurent, Romieu, Charles, Ageorges, Agnes, Klein, Markus, Cheynier, Veronique, Vialet, Sandrine, Terrier, Nancy   +7 more
core   +2 more sources

Loss of CD98HC phosphorylation by ATM impairs antiporter trafficking and drives glutamate toxicity in Ataxia telangiectasia

Nature Communications
Ataxia-telangiectasia is a rare genetic disorder characterized by neurological defects, immunodeficiency, cancer predisposition, radiosensitivity, decreased blood vessel integrity, and diabetes. ATM, the protein mutated in Ataxia-telangiectasia, responds
July Carolina Romero, Sonal S. Tonapi, Manish Parihar, Eva Loranc, Henry E. Miller, Liesl A. Lawrence, Nicklas Bassani, Daniel G. Robledo, Lin Cao, Jia Nie, Kairi Kanda, Aiola Stoja, Natalia Garcia, Aparna Gorthi, Brian J. Stoveken, Teresa W-M Fan, Teresa A. Cassel, Shan Zha, James D. Lechleiter, Nicolas Musi, Lily Q. Dong, Andrew N. Lane, Alexander J. R. Bishop   +22 more
doaj   +1 more source

Artificial Cell Catalysts for Biotransformation: Design Principles and Process Integration

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Artificial cell catalysts are emerging as programmable biocatalytic platforms for sustainable molecular conversion. By reconstituting enzymes and functional modules within synthetic compartments, they combine the selectivity of biological catalysis with the design flexibility of synthetic materials.
Iori Kobayashi, Shogo Yoshimoto, Katsutoshi Hori   +2 more
wiley   +1 more source

Adaptive traits in plants for salinity stress tolerance: A critical review

International Journal of Applied and Experimental Biology
Soil salinity negatively affects plants at multiple levels, inducing ionic and metabolic imbalances that directly affect growth and productivity. Plants counter salinity stress through a combination of adaptive traits that facilitate cellular ion ...
Fahad Shafiq, Sumera Anwar, Muhammad Iqbal   +2 more
doaj   +1 more source

Harnessing ferroptosis from multilayer defense networks to nanoplatforms for specific cancer therapy

BMEMat, EarlyView.
Nanomaterials target metabolically‐regulated ferroptosis for cancer therapy. Iron‐based or alternative nanoplatforms integrate ferroptosis with chemotherapy, immunotherapy, or radiotherapy. They enable stimulus‐responsive therapies (photothermal, photodynamic, sonodynamic) activated by near‐infrared, light, or ultrasound, achieving potent synergistic ...
Xinyue Xu, Xuejian Wang, Wenyan Jiang, Wan Hairul Anuar Kamaruddin, Chunyan Fang, Pengfei Zhang   +5 more
wiley   +1 more source

Evidence of differential pH regulation of the Arabidopsis vacuolar Ca 2+/H+ antiporters CAX1 and CAX2 [PDF]

, 2005
The Arabidopsis Ca2+/H+ antiporters cation exchanger (CAX) 1 and 2 utilise an electrochemical gradient to transport Ca2+ into the vacuole to help mediate Ca2+ homeostasis.
Shigaki, Toshiro, Kendal D. Hirschi, Hirschi, Kendal D., Toshiro Shigaki, Pittman, Jon K.; id_orcid, Pittman, Jon K., Jon K. Pittman   +6 more
core   +1 more source

Dapagliflozin alleviates high‐fat‐induced obesity cardiomyopathy by inhibiting ferroptosis

ESC Heart Failure, Volume 12, Issue 2, Page 1358-1373, April 2025.
Abstract Aim: Dapagliflozin (Dapa) is a novel hypoglycaemic agent with multiple cardiovascular protective effects, and it is widely used in treatment of heart failure patients, but whether it can improve obese phenotype of heart failure and its mechanism is still unclear.
Di Chen, Jiahao Shi, Yue Wu, Lizhu Miao, Zilin Wang, Yixuan Wang, Siwei Xu, Yu Lou   +7 more
wiley   +1 more source

Functional Interaction between the N and C Termini of NhaD Antiporters from Halomonas sp. Strain Y2

, 2017
Two NhaD-type antiporters, NhaD1 and NhaD2, from the halotolerant and alkaliphilic Halomonas sp. strain Y2, exhibit different physiological functions in regard to Na + and Li ...
Huijia Yin, Ping Xu, Yiwei Meng, Bin Cheng, Chunyu Yang, Xinyu Nie, Zhou Yang, Shannan Li   +7 more
core   +1 more source