Results 41 to 50 of about 1,353 (191)

The effects of a plant proteinase inhibitor from Enterolobium contortisiliquum on human tumor cell lines [PDF]

open access: yes, 2011
Supplementary to the efficient inhibition of trypsin, chymotrypsin, plasma kallikrein, and plasmin already described by the EcTI inhibitor from Enterolobium contortisiliquum, it also blocks human neutrophil elastase (K(iapp)=4.3 nM) and prevents phorbol ...
Bhoola K.D.   +16 more
core   +1 more source

Cystatin C deficiency in human atherosclerosis and aortic aneurysms [PDF]

open access: yes, 2014
The pathogenesis of atherosclerosis and abdominal aortic aneurysm involves breakdown of the elastic laminae. Elastolytic cysteine proteases, including cathepsins S and K, are overexpressed at sites of arterial elastin damage, but whether endogenous local
Chapman, Harold A.   +8 more
core   +1 more source

Denning in brown bears

open access: yesEcology and Evolution, Volume 10, Issue 13, Page 6844-6862, July 2020., 2020
The period of hibernation in the brown bear allows it to face the adverse climatic conditions of the scarce of food during the winter. In this study, we review the published literature on this topic and approach it from the perspective of den chronology, den selection, and physiology of hibernation.
Enrique González‐Bernardo   +4 more
wiley   +1 more source

Anti-ophidian activity of Bredemeyera floribunda Willd. (Polygalaceae) root extract on the local effects induced by Bothrops jararacussu venom

open access: yesBrazilian Journal of Medical and Biological Research, 2018
Bredemeyera floribunda roots are popularly used to treat snakebites in the semiarid region of Northeast Brazil, and previous studies indicate the anti-ophidian actions of triterpenoid saponins found in its roots. To assess B.
N.T.Q. Alves   +15 more
doaj   +1 more source

The lumbrical muscle: a novel in situ system to evaluate adult skeletal muscle proteolysis and anticatabolic drugs for therapeutic purposes [PDF]

open access: yes, 2011
Bergantin LB, Figueiredo LB, Godinho RO. the lumbrical muscle: a novel in situ system to evaluate adult skeletal muscle proteolysis and anticatabolic drugs for therapeutic purposes. J Appl Physiol 111: 1710-1718, 2011. First published September 15, 2011;
Fulks RM   +7 more
core   +1 more source

NEW BIOCHEMICAL MARKERS OF RECURRENCE OF PROSTATE CANCER AFTER HIS TREATMENT

open access: yesВестник урологии, 2013
We studied the condition of the blood proteolytic systems (activity of kallikrein (К) and level of prekallikrein (PK), the total proteolytic activity of serine proteinases and elastase-like activity, the leukocytic elastase (LE) activity, the angiotensin-
M. B. Chibichyan   +2 more
doaj   +1 more source

Novel treatment strategies for chronic kidney disease: insights from the animal kingdom [PDF]

open access: yes, 2018
Many of the >2 million animal species that inhabit Earth have developed survival mechanisms that aid in the prevention of obesity, kidney disease, starvation, dehydration and vascular ageing; however, some animals remain susceptible to these ...
Arnold, Walter   +7 more
core   +1 more source

Cluster analysis of immunological serum markers in patients with Parkinson’s disease

open access: yesАнналы клинической и экспериментальной неврологии, 2019
Introduction. The study of patients biological features, including their immune responses, in specific diseases, is an important step towards personalized diagnosis and treatment.
Tatyana P. Klyushnik   +4 more
doaj   +1 more source

In vitro and in vivo anticancer properties of a Calcarea carbonica derivative complex (M8) treatment in a murine melanoma model [PDF]

open access: yes, 2010
Background: Melanoma is the most aggressive form of skin cancer and the most rapidly expanding cancer in terms of worldwide incidence. Chemotherapeutic approaches to treat melanoma have had only marginal success.
Fernando SF Guimarães   +46 more
core   +2 more sources

Concentration-dependent effects of native and polymerised α1-antitrypsin on primary human monocytes, in vitro

open access: yesBMC Cell Biology, 2004
Summary Background α1-antitrypsin (AAT) is one of the major serine proteinase inhibitors controlling proteinases in many biological pathways. There is increasing evidence that AAT is able to exert other than antiproteolytic effects.
Jansson Lennart   +2 more
doaj   +1 more source

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