Results 61 to 70 of about 1,353 (191)

Unraveling the cytotoxic potential of Temozolomide loaded into PLGA nanoparticles [PDF]

, 2014
BACKGROUND: Nanotechnology has received great attention since a decade for the treatment of different varieties of cancer. However, there is a limited data available on the cytotoxic potential of Temozolomide (TMZ) formulations.
Amrita N Bajaj, Darshana S Jain, Peeyush N Goel, Rajani B Athawale, Rajiv P Gude, Shruti S Shrikhande, Yuvraj Nikam   +6 more
core   +1 more source

Identification of the Hub Gene LDB3 in Stanford Type A Aortic Dissection Based on Comprehensive Bioinformatics Analysis

Journal of Cellular and Molecular Medicine, Volume 29, Issue 6, March 2025.
ABSTRACT Stanford type A aortic dissection (TAAD) is a life‐threatening disease. This study explored the role of LIM domain binding 3 (LDB3) in TAAD progression. Four datasets from the Gene Expression Omnibus were analyzed to identify TAAD‐related hub genes. LDB3 single nucleotide polymorphisms (SNPs) were assessed in the UK Biobank.
Xinyi Liu, Xing Liu, Bin Wan, Yipeng Ge, Haiou Hu, Hong Yu, Meng Zhao, Huadong Li, Junming Zhu   +8 more
wiley   +1 more source

Mesenchymal Stromal Cells to Regenerate Emphysema:On the Horizon? [PDF]

, 2018
Mesenchymal stem or stromal cells (MSCs) are multipotent cells that play a pivotal role in various phases of lung development and lung homeostasis, and potentially also lung regeneration.
Heijink, Irene H, Kruk, Dennis M L W, Slebos, Dirk-Jan, Ten Hacken, Nick H, Timens, Wim   +4 more
core   +1 more source

BRCA1 loss activates cathepsin L–mediated degradation of 53BP1 in breast cancer cells [PDF]

, 2013
Loss of 53BP1 rescues BRCA1 deficiency and is associated with BRCA1-deficient and triple-negative breast cancers (TNBC) and with resistance to genotoxic drugs.
Abena B. Redwood, Adriana Dusso, Alvarez-Díaz, Aly, Anna Novell, Bhattacharyya, Blagosklonny, Bochar, Bothmer, Bouwman, Bryant, Bunting, Cao, Cao, David A. Grotsky, Deng, Drew, Duncan, Dusso, Enrique Lerma, Evers, Farmer, Fernandez-Capetillo, Fong, Foulkes, Gartner, Gocheva, Gonzalez-Suarez, Gonzalez-Suarez, Goulet, Helleday, Ignacio Gonzalez-Suarez, Iliakis, Jedeszko, Junran Zhang, Kawai, Lankelma, Martin A. Neumann, Monica Croke, Montserrat Martinez-Alonso, Moynahan, Mullan, Neuhausen, Olive, Pallares, Peppone, Redwood, Redwood, Schlegel, Schultz, Scully, Scully, Scully, Sherley, Shukla, Skrzydlewska, Snouwaert, Sree C. Yaddanapudi, Sung, Susana Gonzalo, Sylvia Ortega-Martinez, Tanic, Teresa Ramon y Cajal, Tu, Turner, Tutt, Wang, Ward, Wooster, Xavier Matias-Guiu, Xie, Xu, Zhihui Feng, Zhu   +73 more
core   +4 more sources

Nutritional Innovation Using Green Seaweed (Ulva sp.) and Garlic Powder Extracts for White‐Leg Shrimp (Litopenaeus vannamei) Challenged by Vibrio harveyi

Veterinary Medicine and Science, Volume 10, Issue 6, November 2024.
Ethanolic extracts from Ulva sp. and garlic powder were tested against Vibrio harveyi. Supplementing white‐leg shrimp diets with these compounds increased immune responses and disease resistance, suggesting potential health and disease management benefits. ABSTRACT This study aimed to determine the antimicrobial effects of ethanolic extracts of Ulva sp.
Nashwa Abdel‐Razek, Riad H. Khalil, Abeer A. M. Afifi, Afrah F. Alkhuriji, Dina M. Metwally   +4 more
wiley   +1 more source

Study on the growth promoting capacity of calf and fetal bovine serum for animal cells "in vitro" II: electrophoretic study and survey on the antiproteolytic activity of pools of calf and fetal bovine serum Estudo sobre a capacidade promotora de crescimento de soros de vitelas e de soros fetais bovinos para células de origem animal cultivadas "in vitro" II: estudo eletroforético e pesquisa da atividade antiproteolítica de soros de vitelas e de soros fetais bovinos

Revista do Instituto de Medicina Tropical de São Paulo, 1984
Calf serum and fetal bovine serum present great variability as to its growth promoting efficiency (GPE). As supplement of culture media to cultivate cells of animal origin they stimulate the "in vitro" multiplication and maintain cell viability.
Edda de Rizzo, Celidéia Aparecida Coppi Vaz, Inácio França Mendes, Anatércia Ferreira Bonfim Yano   +3 more
doaj  

Four‐Dimensional Flow MRI‐Derived Hemodynamics in Abdominal Aortic Aneurysms: Reproducibility and Associations With Diameter, Intraluminal Thrombus Volume, and Vorticity

Journal of Magnetic Resonance Imaging, Volume 60, Issue 3, Page 878-888, September 2024.
Background Maximum diameter measurements are used to assess the rupture risk of abdominal aortic aneurysms (AAAs); however, these are not precise enough to predict all ruptures. Four‐dimensional (4D) flow MRI‐derived parameters provide additional information by visualizing hemodynamics in AAAs but merit further investigation before they are clinically ...
Eva Aalbregt, Reza Indrakusuma, Hamid Jalalzadeh, R. Nils Planken, Joost van Schuppen, Lilian Meijboom, Ron Balm, Aart J. Nederveen, Kak Khee Yeung, Pim van Ooij   +9 more
wiley   +1 more source

Alpha-2-macroglobulin levels in early respiratory distress syndrome

The Turkish Journal of Pediatrics, 1998
The vasoactive products of uncontrolled protease activity can play an important role in the pathogenesis of respiratory distress syndrome in newborn infants.
M Yurdakök, S Yiğit, B Gürakan, S Dündar, S Kirazli   +4 more
doaj  

Effects of zoledronic acid on proteinase plasma levels in patients with bone metastases. [PDF]

, 2006
Background: The effects of the bisphosphonate derivative zoledronic acid (ZA) on the > circulating levels of matrix metalloproteinase-2 (MMP-2), matrix metallo-proteinases-9 > (MMP-9), cathepsin B (Cath B) and urokinase-type plasminogen activator (uPA)
ARCARA, Carmelo Carlo, BADALAMENTI, Giuseppe, CRESCIMANNO, Marilena, FLANDINA, Carla, FULFARO, Fabio, GEBBIA, Nicolo', INCORVAIA, Lorena, LETO, Gaetano, TUMMINELLO, Francesca Maria   +8 more
core  

Acid-Stable Serine Proteinase Inhibitors in the Urine of Alzheimer Disease Subjects [PDF]

, 1996
A comparative study of the levels of acid-stable proteinase inhibitors (kallikrein and trypsin inhibitors) in the urine of healthy and Alzheimer subjects, of both sexes, has been performed.
Angeletti, M., Bonaiuto, S., Eleuteri, A. M., Fioretti, E., Galdenzi, G., Giannandrea, E., Giulio Lupidi, Sparro, G., Tacconi, R., Vesprini, A.   +9 more
core   +2 more sources