Results 31 to 40 of about 181,112 (317)

Electrode‐supported and free‐standing bilayer lipid membranes: Formation and uses in molecular electrochemistry

open access: yesElectrochemical Science Advances, Volume 2, Issue 6, December 2022., 2022
Abstract This short review is aimed at emphasizing the recent most prominent advances in the electrochemical investigation of the interactions of molecules with purely lipid bilayers. The first part which deals with electrode‐supported bilayer lipid membranes is articulated around the nature of electrode material with a focus on mercury to celebrate ...
Eric Labbé, Olivier Buriez
wiley   +1 more source

Advances in electrochemical detection methods for measuring contaminants of emerging concerns

open access: yesElectrochemical Science Advances, Volume 2, Issue 6, December 2022., 2022
Abstract The presence of contaminants of emerging concerns (CECs) such as pharmaceuticals and personal care products, endocrine disrupting compounds (EDCs), per/poly‐fluorinated substances (PFAS), pesticides, and nanomaterials poses significant challenges to the environment and human health.
Mohamed H. Hassan   +2 more
wiley   +1 more source

Comparison of intramuscular haloperidol and other short-acting injectable antipsychotics for management of acute agitation in an adult inpatient psychiatry unit [PDF]

open access: yesMental Health Clinician
Introduction There is no consensus on the optimal antipsychotic for acute agitation. Whereas haloperidol is frequently used and has proven efficacy, second generation antipsychotics show similar efficacy and improved safety and tolerability.
Sarah Gamcsik, PharmD   +1 more
doaj   +1 more source

Preclinical common data elements for general pharmacological studies (pharmacokinetic sample collection, tolerability, and drug administration). A report of the TASK3‐WG1A General Pharmacology Working Group of the ILAE/AES Joint Translational Task Force

open access: yesEpilepsia Open, EarlyView., 2023
Abstract Growing concerns over rigor and reproducibility of preclinical studies, including consistency across laboratories and translation to clinical populations, have triggered efforts to harmonize methodologies. This includes the first set of preclinical common data elements (CDEs) for epilepsy research studies, as well as Case Report Forms (CRFs ...
Lisa Coles   +9 more
wiley   +1 more source

Targeted learning in observational studies with multi-valued treatments: An evaluation of antipsychotic drug treatment safety [PDF]

open access: yesarXiv, 2022
We investigate estimation of causal effects of multiple competing (multi-valued) treatments in the absence of randomization. Our work is motivated by an intention-to-treat study of the relative cardiometabolic risk of assignment to one of six commonly prescribed antipsychotic drugs in a cohort of nearly 39,000 adults with serious mental illnesses ...
arxiv  

Antipsychotic Medication for Prevention and Treatment of Delirium in Hospitalized Adults: A Systematic Review and Meta‐Analysis

open access: yesJournal of The American Geriatrics Society, 2016
To evaluate the effectiveness of antipsychotic medications in preventing and treating delirium.
K. Neufeld   +4 more
semanticscholar   +1 more source

Exploring Neuronal Bistability at the Depolarization Block [PDF]

open access: yes(2012) PLoS ONE 7(8): e42811, 2012
Many neurons display bistability - coexistence of two firing modes such as bursting and tonic spiking or tonic spiking and silence. Bistability has been proposed to endow neurons with richer forms of information processing in general and to be involved in short-term memory in particular by allowing a brief signal to elicit long-lasting changes in ...
arxiv   +1 more source

Alternative initiation regimen of paliperidone palmitate long-acting injectable

open access: yesEuropean Psychiatry, 2022
Introduction Long-acting injectable antipsychotics (LAIs) hold an important place in the treatment of psychosis. Knowledge of the best way to administer LAIs is important to maximize the efficacy and minimize the side-effects Objectives To assess the ...
I.E. Menendez Gil   +2 more
doaj   +1 more source

Attentional M100 gain modulation localizes to auditory sensory cortex and is deficient in first‐episode psychosis

open access: yesHuman Brain Mapping, Volume 44, Issue 1, Page 218-228, January 2023., 2023
The use of magnetoencephalography and the Human Connectome Project multimodal parcellation revealed precise cortical areas underlying attention modulation of auditory sensory activity in healthy individuals and impairments in early psychosis. The sensory reduction and attention modulation impairment indicate pathophysiology proximal to disease onset ...
Mark T. Curtis   +3 more
wiley   +1 more source

Risperidone-induced tardive akathisia: A rare antipsychotic side effect with management issues

open access: yesAnnals of Indian Academy of Neurology, 2019
Akathisia is a movement disorder, a common extrapyramidal side effect that has been reported to occur primarily with antipsychotics and some neurological conditions.
Biswa Ranjan Mishra   +3 more
doaj   +1 more source

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