Results 31 to 40 of about 195,206 (338)

Adjunctive quetiapine for serotonin reuptake inhibitor-resistant obsessive-compulsive disorder: A meta-analysis of randomised controlled treatment trials [PDF]

, 2006
Small studies have shown positive effects from adding a variety of antipsychotic agents in patients with obsessive–compulsive disorder who are unresponsive to treatment with serotonin reuptake inhibitors. The evidence, however, is contradictory.
Carey, P, Denys, D, Fineberg, N, Premkumar, P, Seedat, S, Sivakumaran, T, Stein, DJ, Vythilingum, B, Westenberg, H   +8 more
core   +1 more source

Metabotropic glutamate 2/3 receptors and epigenetic modifications in psychotic disorders: a review [PDF]

, 2016
Schizophrenia and Bipolar Disorder are chronic psychiatric disorders, both considered as "major psychosis"; they are thought to share some pathogenetic factors involving a dysfunctional gene x environment interaction.
Grayson, Danis R, Guidotti, Alessandro, MATRISCIANO, FRANCESCO, NICOLETTI, Ferdinando, PANACCIONE, ISABELLA   +4 more
core   +2 more sources

Effects of intervention with the SAFE strategy on trachoma across Ethiopia.

, 2011
BACKGROUND/AIMS: The impact of the SAFE strategy (surgery, antibiotics, face washing, environmental hygiene), recommended to eliminate blinding trachoma, is not well explored.
Patel, D, Roba, AA, Wondimu, A, Zondervan, M   +3 more
core   +1 more source

The influence of 5-HT(2C) and MDR1 genetic polymorphisms on antipsychotic-induced weight gain in female schizophrenic patients [PDF]

, 2008
We investigated the relationships between functional genetic variants of the 5-HT(2C) receptor and multidrug-resistant protein (MDR1), coding for P-glycoprotein, and second generation antipsychotic (SDA)-induced weight gain among 108 female schizophrenic
Bilušić, Hrvoje, Božina, Nada, Hotujac, Ljubomir, Medved, Vesna, Rojnić Kuzman, Martina, Šain, Ivica   +5 more
core   +1 more source

Challenges and pitfalls of antipsychotic prescribing in people with learning disability [PDF]

, 2017
No abstract ...
Alexander, Regi T., Bhaumik, Sabyasachi, Cooper, Sally A., Hastings, Richard, Kapugama, Chaya L., Roy, Ashok, Shankar, Rohit, Tromans, Samuel J.   +7 more
core   +1 more source

Antipsychotic-Related Risks of Type 2 Diabetes Mellitus in Enrollees With Schizophrenia in the National Basic Public Health Service Program in Hunan Province, China

Frontiers in Psychiatry, 2022
BackgroundAntipsychotics contribute to the development of type 2 diabetes mellitus (T2DM) in individuals with schizophrenia. However, the extent of the relationship between antipsychotic use and T2DM varies in different settings, and the magnitude of the
Feiyun Ouyang, Jun He, Xunjie Cheng, Wei Zhou, Shuiyuan Xiao, Junqun Fang   +5 more
doaj   +1 more source

A Systematic Review of the Soteria Paradigm for the Treatment of People Diagnosed With Schizophrenia [PDF]

, 2008
Background: The “Soteria paradigm” attempts to support people diagnosed with schizophrenia spectrum disorders using a minimal medication approach. Interest in this approach is growing in the United Kingdom, several European countries, North America, and ...
Calton, Tim, Ferriter, Michael, Huband, Nick, Spandler, Helen   +3 more
core   +2 more sources

Early improvements of individual symptoms as a predictor of treatment response to asenapine in patients with schizophrenia

Neuropsychopharmacology Reports, 2020
Aim It is well accepted that early improvement with antipsychotics predicts subsequent response in patients with schizophrenia. However, no study has examined the contribution of individual symptoms rather than overall symptom severity as the predictors.
Kamiyu Ogyu, Yoshihiro Noda, Kazunari Yoshida, Shin Kurose, Fumi Masuda, Yu Mimura, Hana Nishida, Eric Plitman, Ryosuke Tarumi, Sakiko Tsugawa, Masataka Wada, Takahiro Miyazaki, Hiroyuki Uchida, Ariel Graff‐Guerrero, Masaru Mimura, Shinichiro Nakajima   +15 more
doaj   +1 more source

Antipsychotic drugs elicit cytotoxicity in glioblastoma multiforme in a calcium‐dependent, non‐D2 receptor‐dependent, manner

Pharmacology Research & Perspectives, 2021
Dopamine D2‐like receptor antagonists have been suggested as being potential anticancer therapeutics with specific utility for central nervous system cancers due to their ability to cross the blood‐brain barrier.
Jillian S. Weissenrieder, Jessie L. Reed, George‐Lucian Moldovan, Martin T. Johnson, Mohamed Trebak, Jeffrey D. Neighbors, Richard B. Mailman, Raymond J. Hohl   +7 more
doaj   +1 more source

Successful high dose antipsychotic treatment with cariprazine in patients on the schizophrenia spectrum: Real-world evidence from a Spanish hospital setting

Frontiers in Psychiatry, 2023
Real-world evidence fills in an important gap by providing data on the effectiveness and tolerability of new medications in everyday patients. In this data collection form a Spanish hospital, the effectiveness and tolerability of cariprazine were ...
Lluis Niell Galmes, Elmars Rancans
doaj   +1 more source