Results 61 to 70 of about 195,206 (338)

Neurocognitive Correlates of Treatment Response in Children with Tourette\u27s Disorder [PDF]

open access: yes, 2018
This paper examined neurocognitive functioning and its relationship to behavior treatment response among youth with Tourette\u27s Disorder (TD) in a large randomized controlled trial.
Chang, Susanna W.   +8 more
core   +2 more sources

Quality indicators for safe and effective use of medications in long‐term care settings: A systematic review

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
People accessing aged care services are increasingly older and often experience multimorbidity and polypharmacy, which puts them at risk of medication‐related harm. Quality indicators (QIs) can assist with monitoring, benchmarking and informing initiatives to reduce medication‐related harm.
Daria S. Gutteridge   +20 more
wiley   +1 more source

Clozapine-Encapsulated Binary Mixed Micelles in Thermosensitive Sol–Gels for Intranasal Administration

open access: yesGels, 2022
(1) Background: Clozapine is the most effective antipsychotic. It is, however, associated with many adverse drug reactions. Nose-to-brain (N2B) delivery offers a promising approach.
Madeleine S. A. Tan   +5 more
doaj   +1 more source

Problems associated with the diagnosis and the prescribing of anti-psychotic medication in children and adolescents for psychiatric conditions, by non-psychiatric specialists [PDF]

open access: yes, 2009
Aim: The objective of this study is to assess the accuracy of the diagnosis and appropriateness of antipsychotic medication prescribed to children and adolescents referred to child guidance clinic, and how many of these remained on the said medication ...
Camilleri, Nigel   +2 more
core  

Comparative analysis of the characteristics and trends of adverse drug reaction reports from patients in Japan and the Japanese Adverse Drug Event Report database

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Spontaneous reporting of adverse drug reactions (ADR) after a product has reached the market is essential for drug safety. This study analysed patient ADR reports and compared them with reports from the Japanese Adverse Drug Event Report (JADER) database to identify differences and trends.
Masami Tsuchiya   +5 more
wiley   +1 more source

The diagnostic dilemma in a patient with neuroleptic malignant syndrome during the COVID‐19 pandemic: A significant increase in acute phase reactants

open access: yesClinical Case Reports, 2023
Key Clinical Message In some patients, neuroleptic malignant syndrome is accompanied significant high levels of erythrocyte sedimentation rate (ESR), C‐reactive protein (CRP).
Forouzan Elyasi   +5 more
doaj   +1 more source

N-Skatyltryptamines—Dual 5-HT6R/D2R Ligands with Antipsychotic and Procognitive Potential

open access: yesMolecules, 2021
A series of N-skatyltryptamines was synthesized and their affinities for serotonin and dopamine receptors were determined. Compounds exhibited activity toward 5-HT1A, 5-HT2A, 5-HT6, and D2 receptors.
Agata Hogendorf   +13 more
doaj   +1 more source

Evidence and Extrapolation: Mechanisms for Regulating Off-Label Uses of Drugs and Devices [PDF]

open access: yes, 2014
A recurring, foundational issue for evidence-based regulation is deciding whether to extend governmental approval from an existing use with sufficient current evidence of safety and efficacy to a novel use for which such evidence is currently lacking ...
Abbott, Ryan, Ayres, Ian
core   +3 more sources

Antipsychotic Polypharmacy

open access: yesFocus, 2020
Physicians who treat patients with schizophrenia frequently encounter complex clinical situations not fully addressed by published treatment guidelines. Some of these situations lead to antipsychotic polypharmacy, often prescribed when clinical and social obstacles prevent access to clozapine and patients have had suboptimal responses to nonclozapine ...
Adriana, Foster, Jordanne, King
openaire   +3 more sources

Cannabinoids From Trema micranthum (L.) Blume (Cannabaceae): A Cannabinoid Profiling System

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT Trema micranthum (L.) Blume is a species from the Cannabaceae botanical family, present all over the tropics. A recent study conducted by our group identified the presence of cannabidiol (CBD), Δ9‐tetrahydrocannabinol, cannabidiolic acid, and tetrahydrocannabinolic acid‐A in T. micranthum extracts.
Yasmin Cunha‐Silva   +7 more
wiley   +1 more source

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