Results 61 to 70 of about 201,990 (292)
Psychoactive prescription drug use and misuse in patients on opioid agonist treatment
British Journal of Clinical Pharmacology, EarlyView.Aims To identify the patterns and trends in prescription drug use and misuse in patients on opioid agonist treatment. Methods We used data from the OPPIDUM programme, which collects data from patients attending substance abuse treatment facilities. Data collected include use of psychoactive prescription drugs in the past week.
Thomas Soeiro +5 more
wiley +1 more source
Clinical Case Reports, 2023 Key Clinical Message In some patients, neuroleptic malignant syndrome is accompanied significant high levels of erythrocyte sedimentation rate (ESR), C‐reactive protein (CRP).
Forouzan Elyasi +5 more
doaj +1 more source
N-Skatyltryptamines—Dual 5-HT6R/D2R Ligands with Antipsychotic and Procognitive Potential
Molecules, 2021 A series of N-skatyltryptamines was synthesized and their affinities for serotonin and dopamine receptors were determined. Compounds exhibited activity toward 5-HT1A, 5-HT2A, 5-HT6, and D2 receptors.
Agata Hogendorf +13 more
doaj +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aims Pain is common in patients with Crohn's disease (CD) and ulcerative colitis (UC), and a substantial proportion develop chronic opioid use (COU). We examined the persistence of COU over time and identified factors predicting persistent use. Methods This nationwide Danish cohort study included patients with an initial period of COU (definition: ≥3 ...
Bente Mertz Nørgård +6 more
wiley +1 more source
Frontiers in Neuroscience, 2011 The lack of predictive in vitro models for behavioral phenotypes impedes rapid advancement in neuropharmacology and psychopharmacology. In vivo behavioral assays are more predictive of activity in human disorders, but such assays are often highly ...
Steven L Roberds +5 more
doaj +1 more source
Noninvasive drug adherence monitoring of antipsychotic patients via finger sweat testing
Frontiers in Chemistry, 2023 Collection of finger sweat is explored here as a rapid and convenient way of monitoring patient adherence to antipsychotic drugs. Finger sweat samples (n = 426) collected from patients receiving treatment with clozapine, quetiapine and olanzapine were ...
K. Longman +7 more
doaj +1 more source
Methylation age acceleration does not predict mortality in schizophrenia. [PDF]
, 2019 Schizophrenia (SCZ) is associated with high mortality. DNA methylation levels vary over the life course, and pre-selected combinations of methylation array probes can be used to estimate "methylation age" (mAge). mAge correlates highly with chronological
Burrage, Joe +7 more
core +1 more source
Clinical pharmacology consultations and their implementation in clinical decision making
British Journal of Clinical Pharmacology, EarlyView.Aims One of the key roles of clinical pharmacologists is to work as consultants for other medical specialties. We wanted to investigate the characteristics of clinical pharmacology consultations, compare the types of consultations from different specialties, and evaluate how well the recommendations given were followed.
Mirjam Kauppila +2 more
wiley +1 more source
An Audit on the Monitoring and Management of Hyperprolactinemia in Inpatient Adults on Regular Antipsychotics in 8 Acute Wards in an NHS Mental Health Trust [PDF]
, 2022 Peter Zhang, Zhen Dong Li
openalex +1 more source
The phytocannabinoid, Δ(9) -tetrahydrocannabivarin, can act through 5-HT1 A receptors to produce antipsychotic effects [PDF]
, 2015 Funded by: •GW Pharmaceuticals Acknowledgements: The authors wish to thank Mrs Lesley Stevenson for technical support and Dr John Raymond, Dr Keith Parker and Dr Ethan Russo for providing human 5-HT1A CHO cells.
Cascio, Maria Grazia +4 more
core +1 more source