Results 61 to 70 of about 195,206 (338)
Neurocognitive Correlates of Treatment Response in Children with Tourette\u27s Disorder [PDF]
This paper examined neurocognitive functioning and its relationship to behavior treatment response among youth with Tourette\u27s Disorder (TD) in a large randomized controlled trial.
Chang, Susanna W.+8 more
core +2 more sources
People accessing aged care services are increasingly older and often experience multimorbidity and polypharmacy, which puts them at risk of medication‐related harm. Quality indicators (QIs) can assist with monitoring, benchmarking and informing initiatives to reduce medication‐related harm.
Daria S. Gutteridge+20 more
wiley +1 more source
(1) Background: Clozapine is the most effective antipsychotic. It is, however, associated with many adverse drug reactions. Nose-to-brain (N2B) delivery offers a promising approach.
Madeleine S. A. Tan+5 more
doaj +1 more source
Problems associated with the diagnosis and the prescribing of anti-psychotic medication in children and adolescents for psychiatric conditions, by non-psychiatric specialists [PDF]
Aim: The objective of this study is to assess the accuracy of the diagnosis and appropriateness of antipsychotic medication prescribed to children and adolescents referred to child guidance clinic, and how many of these remained on the said medication ...
Camilleri, Nigel+2 more
core
Aims Spontaneous reporting of adverse drug reactions (ADR) after a product has reached the market is essential for drug safety. This study analysed patient ADR reports and compared them with reports from the Japanese Adverse Drug Event Report (JADER) database to identify differences and trends.
Masami Tsuchiya+5 more
wiley +1 more source
Key Clinical Message In some patients, neuroleptic malignant syndrome is accompanied significant high levels of erythrocyte sedimentation rate (ESR), C‐reactive protein (CRP).
Forouzan Elyasi+5 more
doaj +1 more source
N-Skatyltryptamines—Dual 5-HT6R/D2R Ligands with Antipsychotic and Procognitive Potential
A series of N-skatyltryptamines was synthesized and their affinities for serotonin and dopamine receptors were determined. Compounds exhibited activity toward 5-HT1A, 5-HT2A, 5-HT6, and D2 receptors.
Agata Hogendorf+13 more
doaj +1 more source
Evidence and Extrapolation: Mechanisms for Regulating Off-Label Uses of Drugs and Devices [PDF]
A recurring, foundational issue for evidence-based regulation is deciding whether to extend governmental approval from an existing use with sufficient current evidence of safety and efficacy to a novel use for which such evidence is currently lacking ...
Abbott, Ryan, Ayres, Ian
core +3 more sources
Physicians who treat patients with schizophrenia frequently encounter complex clinical situations not fully addressed by published treatment guidelines. Some of these situations lead to antipsychotic polypharmacy, often prescribed when clinical and social obstacles prevent access to clozapine and patients have had suboptimal responses to nonclozapine ...
Adriana, Foster, Jordanne, King
openaire +3 more sources
Cannabinoids From Trema micranthum (L.) Blume (Cannabaceae): A Cannabinoid Profiling System
ABSTRACT Trema micranthum (L.) Blume is a species from the Cannabaceae botanical family, present all over the tropics. A recent study conducted by our group identified the presence of cannabidiol (CBD), Δ9‐tetrahydrocannabinol, cannabidiolic acid, and tetrahydrocannabinolic acid‐A in T. micranthum extracts.
Yasmin Cunha‐Silva+7 more
wiley +1 more source