Results 91 to 100 of about 96,867 (352)
ChemPhotoChem, EarlyView.The combination of continuous flow technology and visible light photocatalysis has been used to improve the safety and productivity of reactions with diazonium salts as reactive intermediates. This approach has proven to be a reliable method for various organic synthesis routes with diazonium salts under mild and well‐defined conditions.
Christoph Deckers, Thomas H. Rehm
wiley +1 more source
DiffDTM: A conditional structure-free framework for bioactive molecules generation targeted for dual proteins [PDF]
arXiv, 2023 Advances in deep generative models shed light on de novo molecule generation with desired properties. However, molecule generation targeted for dual protein targets still faces formidable challenges including protein 3D structure data requisition for model training, auto-regressive sampling, and model generalization for unseen targets.
arxiv
ANTIPSYCHOTICS- CLASSIFICATION, USES, AND ADVERSE EFFECTS [PDF]
Introduction: Antipsychotic agents are categorized usually as either “typical antipsychotics” or “atypical antipsychotics”. Typical antipsychotic pharmacological agents, which are also called first-generation antipsychotics or traditional antipsychotics,
Mohammed Abdulhakim Hamad Al Hattab , Abdulkhaliq Yahya Mansour Alahmari, Maan Ahmed Alsaaid , Batool Abed Mansoor Ahmed , Malak Saleh Abdullah, Khalid Ali Alharbi , Asma Salem Almatrafi , Nouf Al-Abdulmohsin, Waleed Mohammed Mujalli , Nasser Mansour Khawaji
core +1 more source
Modified Mediterranean Diet for Enrichment of Short Chain Fatty Acids: Potential Adjunctive Therapeutic to Target Immune and Metabolic Dysfunction in Schizophrenia? [PDF]
, 2017 Growing interest in gut and digestive processes and their potential link to brain and peripheral based inflammation or biobehavioral phenotypes has led to an increasing number of basic and translational scientific reports focused on the role of gut ...
Cadenhead, Kristen S +4 more
core +1 more source
Neuroleptic malignant syndrome
Journal of Family Medicine and Primary Care, 2016 Neuroleptic malignant syndrome (NMS) is a life-threatening emergency that is often seen as a complication of antipsychotic agents. It is characterized by a tetrad of motor, behavioral, autonomic, and laboratory abnormalities.
Bino Rajamani +2 more
doaj +1 more source
Overdose profiles of new antipsychotic agents [PDF]
The International Journal of Neuropsychopharmacology, 2000 Although the more recently introduced antipsychotic drugs are increasing in popularity, the pattern of symptomatology when taken in overdose is not well defined. We monitored all enquiries to the National Poisons Information Service, London (NPIS, London) concerning antipsychotic drugs over a 9-month period in 1997 and report our findings concerning ...
John A. Henry +2 more
openaire +3 more sources
Drug Testing and Analysis, EarlyView.Simultaneous qualitative and quantitative analysis of 62 drugs and seven active metabolites in human blood plasma by automated liquid chromatography linear ion trap mass spectrometry. ABSTRACT Rapid and comprehensive qualitative and quantitative analytical procedures are crucial in 24/7 emergency toxicology (ET) to support diagnosis and treatment of ...
Selina Hemmer +4 more
wiley +1 more source
Clozapine: the past, present, and future
Open Journal of Psychiatry and Allied Sciences, 2015 Today even after fifty years of its manufacture the decision to use clozapine still represents a challenge to the clinician because of the complexities involved in accurately assessing its risks and benefits.
Sekh Afrar Alam +2 more
doaj
Recent trends in antipsychotic polypharmacy in the treatment of schizophrenia
Neuropsychopharmacology Reports, 2020 Ichihashi et al reported that 43% of patients had antipsychotic polypharmacy. Number of antipsychotics used in patients with schizophrenia in Japan was the greatest among Asian countries.
Norio Yasui‐Furukori, Kazutaka Shimoda
doaj +1 more source
Cigarette smoking and heavy coffee drinking affect therapeutic response to olanzapine [PDF]
Srpski Arhiv za Celokupno Lekarstvo, 2018 Introduction/Objective. Considering relatively complex pharmacokinetic profile of olanzapine, it is expected that certain medications and some compounds, found in food and drink, can induce or inhibit its metabolism.
Radmanović Branimir +3 more
doaj +1 more source