Results 191 to 200 of about 3,281,120 (365)

PMH26: CHANGE IN HEALTH-RELATED QUALITY OF LIFE IN PATIENTS WITH SCHIZOPHRENIA TAKING ANTIPSYCHOTIC AGENTS

, 2000
WS Edell, MB Durkin, SH Mody, BE Adams, RE White, AZ Qiu   +5 more
openalex   +1 more source

Neurobehavioral and genotoxic parameters of antipsychotic agent aripiprazole in mice [PDF]

, 2011
Jaqueline Nascimento Picada, Bruna de Jesus Neto Dos Santos, Franciele Celso, Jéssica Dias Monteiro, Kelly Morais Da Rosa, Leandro Rosa Camacho, Luciana Vieira, Taís Madelon Freitas, Tatiana Grasiela Da Silva, Viviane Minuzzo Pontes, Patrı́cia Pereira   +10 more
openalex   +1 more source

Plasma Glial Fibrillary Acidic Protein and Neurofilament Light Are Elevated in Bipolar Depression: Evidence for Neuroprogression and Astrogliosis

Bipolar Disorders, EarlyView.
ABSTRACT Background Recent advances now allow detection of brain‐specific proteins in blood, including neurofilament light chain (NfL), a marker of axonal pathology, and glial fibrillary acidic protein (GFAP), indicative of astrocytic activation. Given the evidence of astroglial pathology and neuronal dysfunction in bipolar disorder, and ongoing ...
Matthew J. Y. Kang, Dhamidhu Eratne, Olivia Dean, Michael Berk, Adam J. Walker, Cassandra Wannan, Charles B. Malpas, Claudia Cicognola, Shorena Janelidze, Oskar Hansson, Jasleen Grewal, Philip B. Mitchell, Malcolm Hopwood, Christos Pantelis, Alexander F. Santillo, Dennis Velakoulis   +15 more
wiley   +1 more source

Comparison of Cardiovascular Effects of a New Antipsychotic Agent Aripiprazole with Those of Haloperidol

, 2000
Yoshioki Satoh, Atsushi Sugiyama, Akira Takahara, Keitaro Hashimoto   +3 more
openalex   +1 more source

Relevance of ecological momentary assessment for medication adherence in clinical settings: A precision psychiatry approach

British Journal of Clinical Psychology, EarlyView.
Abstract Background Medication non‐adherence is a leading cause of treatment failure in psychiatric populations. However, current studies highlight the lack of methodological guidance on medication assessments. Ecological Momentary Assessment (EMA), using smartphone‐based evaluations, shows promise for real‐time monitoring in everyday settings.
Valentine Chirokoff, Arnaud Tessier, Fuschia Serre, Maud Dupuy, Marc Auriacombe, Sandra Chanraud, Sylvie Berthoz, Melina Fatseas, David Misdrahi   +8 more
wiley   +1 more source

Preclinical models for evaluating psychedelics in the treatment of major depressive disorder

British Journal of Pharmacology, EarlyView.
Psychedelic drugs have seen a resurgence in interest as a next generation of psychiatric medicines with potential as rapid‐acting antidepressants (RAADs). Despite promising early clinical trials, the mechanisms which underlie the effects of psychedelics are poorly understood.
Laith Alexander, Dasha Anderson, Luke Baxter, Matthew Claydon, James Rucker, Emma S. J. Robinson   +5 more
wiley   +1 more source

Perospirone, a Novel Antipsychotic Agent, Hyperpolarizes Rat Dorsal Raphe Neurons via 5-HT1A Receptor

, 2003
Tsuguka Shiwa, Taku Amano, Hiroaki Matsubayashi, Takahiro Seki, Masashi Sasa, Norio Sakai   +5 more
openalex   +2 more sources

The use of different types of networks, alone and in combination, for drug target identification

British Journal of Pharmacology, EarlyView.
Current therapeutic approaches often focus on targeting clinical symptoms or peripheral phenotypes rather than the underlying molecular mechanisms, or endophenotypes, that drive diseases. While symptom‐based drugs can alleviate discomfort, they do not necessarily alter disease progression and may overlook opportunities for prevention or early ...
Paolo Parini
wiley   +1 more source

Evaluation of the potential of antipsychotic agents to induce catalepsy in rats: Assessment of a new, commercially available, semi-automated instrument [PDF]

, 2014
Barbara A. Bricker, Dinithia Sampson, Seth Y. Ablordeppey   +2 more
openalex   +1 more source

Exploring the pathophysiology underlying clozapine‐induced enhancement of glutamatergic transmission through L‐glutamate and D‐serine release associated with pannexin1 hemichannels

British Journal of Pharmacology, EarlyView.
Abstract Background and purpose Clozapine, an approved antipsychotic for treatment‐resistant schizophrenia (TRS), enhances glutamatergic transmission by increasing exocytosis and non‐exocytosis glutamate release; however, its full action remained to be clarified.
Motohiro Okada, Ruri Okubo, Eishi Motomura   +2 more
wiley   +1 more source