Results 171 to 180 of about 56,519 (290)

Repeated Unstimulated Whole Saliva Collection: A Reliable Approach to Improve Diagnostic Accuracy

open access: yesJournal of Oral Rehabilitation, EarlyView.
Sixty‐two healthy participants provided unstimulated whole saliva by passive drooling for 5 min, three times daily for three consecutive days (nine samples). Single measurements showed high intra‐subject variability and limited reproducibility. Averaging repeated, standardised collections improved reliability and may enhance diagnostic accuracy ...
Gennaro Musella   +7 more
wiley   +1 more source

Parasomnias and sleep‐related movement disorders induced by drugs in the adult population: a review about iatrogenic medication effects

open access: yesJournal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Parasomnias and sleep‐related movement disorders (SRMD) are major causes of sleep disorders and may be drug induced. The objective of this study was to conduct a systematic review of the literature to examine the association between drug use and the occurrence of parasomnias and SRMD.
Sylvain Dumont   +5 more
wiley   +1 more source

Links between trauma and psychotic symptoms: Integrating cognitive behavioural and neuropsychoanalytic models of psychosis

open access: yesPsychology and Psychotherapy: Theory, Research and Practice, EarlyView.
Abstract Purpose Cognitive‐behavioural therapy for psychosis (CBTp) achieves small to modest effect sizes, which invites the question, ‘What clinical modifications might improve outcomes?’ This paper proposes an integration of CBTp with a neuropsychoanalytic approach that in clinical practice might extend the gains achieved by CBTp alone.
Michael Garrett
wiley   +1 more source

Physiological markers of Trauma‐related nightmares among military personnel suffering from PTSD: A multicenter home‐recording study

open access: yesPsychiatry and Clinical Neurosciences, EarlyView.
Aim Despite being one of the most disabling symptoms of post‐traumatic stress disorder (PTSD)—disrupting sleep continuity, reinforcing hyperarousal, and worsening psychiatric comorbidity—the physiological signature of Trauma‐related nightmares (TRNs) under naturalistic sleep conditions remains poorly characterized.
Dorone Feingold   +8 more
wiley   +1 more source

The development of positron emission tomography (PET) tracer for glutamate AMPA receptors and its application to human biology and clinics

open access: yesPsychiatry and Clinical Neurosciences, EarlyView.
Psychiatric and neurological disorders severely compromised patients' quality of life. Despite their urgent needs, the development of diagnostics and therapeutics based on the biological basis has made only little progress. This is due to limited evidence on the biological basis of these disorders in humans. Synapses are fundamental structural units of
Mai Hatano, Hiroki Abe, Takuya Takahashi
wiley   +1 more source

Adverse outcomes between VMAT2 and anticholinergics in tardive dyskinesia: A target trial emulation

open access: yesPsychiatry and Clinical Neurosciences, EarlyView.
Aim Vesicular monoamine transporter 2 (VMAT2) inhibitors have been approved for the treatment of tardive dyskinesia (TD), whereas anticholinergic agents are still widely used for this condition. This study aimed to compare the risk of major clinical adverse outcomes among patients with TD treated with VMAT2 inhibitors versus anticholinergic agents ...
Tien‐Wei Hsu   +13 more
wiley   +1 more source

Changing with the whims of dogs: An inter‐species exploration of self‐alteration with companion animals

open access: yesThe Australian Journal of Anthropology, EarlyView.
Abstract This article offers an alternative understanding to the therapeutic experiences of human interactions with companion species, particularly dogs and horses, through a phenomenological discussion of more‐than‐human intersubjectivity. In an ethnographic account of residents of the Central Coast, New South Wales, Australia, the lived experience of
Katherine Joy Fletcher
wiley   +1 more source

Electromechanical modelling and simulation of human‐induced pluripotent stem cell‐derived cardiomyocytes predict drug‐induced contractility effects

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend A study described in this paper describes a new tool for hiPSC‐CM electromechanical behaviour simulations using mathematical modelling. The model enables in silico assays making drug testing quick, comprehensive and accurate. New hiPSC‐CM models can be used as a platform to integrate in vitro and in silico findings.
Milda Folkmanaite   +9 more
wiley   +1 more source

Psychotropic medication and the fetal brain

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Brain region changes linked to in‐utero psychotropic exposure. Abstract Medications known to cross the blood–brain barrier (psychotropic medications) are commonly prescribed to women during pregnancy, often for the management of mental illness.
Oliver Gale‐Grant, Tomoki Arichi
wiley   +1 more source

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