Results 161 to 170 of about 32,966 (252)

Neurocognitive Aging Following Acute Illness: Pathobiology and a Framework for Developing Neurotherapeutic Agents

Brain and Behavior, Volume 16, Issue 6, June 2026.
In this review, we discuss the scientific basis for how neurocognitive aging occurs after critical illness, including sepsis, trauma, and burns, and the clinical need to develop therapies to reduce inflammation, protect the blood–brain barrier, remove senescent cells, and enhance neuroplasticity.
Errin Lawrence, Daniel Fulton, Poppy Brown, Subashini Suresh, Mark Morris, Paraskevi Goggolidou, Sree Chaithanya, Marcus Abbawy, Amelia Wild, Prashant Nasa, Niharika A. Duggal, Fang Gao‐Smith, Zubair Ahmed, Suresh Renukappa, Tonny Veenith   +14 more
wiley   +1 more source

Revisiting the Management of Treatment-Resistant Depression. [PDF]

Can J Psychiatry
Lee JJ, Blumberger DM.
europepmc   +1 more source

Idiopathic Granulomatous Mastitis in a Nulliparous Woman With Autism Spectrum Disorder Receiving Long‐Term Psychotropic Treatment and Normal Serum Prolactin Level: A Case Report

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Idiopathic granulomatous mastitis (IGM) is a rare inflammatory breast disorder, primarily attributed to immunological dysregulation, hormonal imbalances, or fertility‐related conditions. We report a 26‐year‐old female with autism spectrum disorder (ASD) under long‐term multidrug psychotropic treatment who developed IGM.
Esmat Davoudi‐Monfared, Fatemeh Shahabi, Asieh Sadat Fattahi, Marzieh Rahimi, Mahsa Akbari Oryani, Azadeh Jabbari Nooghabi   +5 more
wiley   +1 more source

Next-step treatment for schizophrenia non-responsive to antipsychotics: a systematic review and network meta-analysis. [PDF]

EClinicalMedicine
Furukawa Y, Salahuddin NH, Wei Y, Pinioti E, Kim DD, Milosavlijević F, Siafis S, Schneider-Thoma J, Samara M, Bighelli I, Leucht S.   +10 more
europepmc   +1 more source

From Molecules to Machines: An Integrative Framework Linking Molecular Pathogenesis, Multi‐Factorial Risk, Risk Stratification, Clinical Management, and Artificial Intelligence in QT Prolongation and Sudden Cardiac Death

Clinical Cardiology, Volume 49, Issue 6, June 2026.
An integrative conceptual framework linking the five principal domains addressed in this review. Beginning at the molecular level, loss‐of‐function mutations in KCNQ1 and KCNH2 reduce outward repolarizing currents (IKs and IKr), while gain‐of‐function SCN5A mutations augment late inward sodium current (INa), establishing the genetic substrate for ...
Mojtaba Farjam, Mohammad Hosein Yazdanpanah, Narges Fereydouni   +2 more
wiley   +1 more source

Improvement in Antipsychotic-Related Sexual Dysfunction After Switching to Cariprazine: A Prospective Real-World Study. [PDF]

J Clin Med
Montejo ÁL, Fiorini JC, Megía P, Ochoa R, Arribas B, Peraire M, Echeverria I, Aparicio E, García-Ullán L.   +8 more
europepmc   +1 more source

Association of Neurodevelopmental Disorders and Congenital Anomalies With Prenatal Multiple Sclerosis Treatment—Real‐World Historical Cohort Study

Clinical Pharmacology &Therapeutics, Volume 119, Issue 6, Page 1565-1573, June 2026.
There is a paucity of data regarding the effects of prenatal disease‐modifying therapies (DMTs) for multiple sclerosis (MS), on congenital anomalies in the offspring. Moreover, data on the association with neurodevelopmental disorders are lacking. This is an historical cohort study, within the Israeli Clalit Health Services database (2005–2024) that ...
Bar Rosh, Ofek Levi, Nili Stein, Amir Yahav, Naomi Gronich   +4 more
wiley   +1 more source

Tooth Loss and Uncontrolled Diabetes Among Korean Adults With Type 2 Diabetes: Insights From the Korea National Health and Nutrition Examination Survey (KNHANES) 2014–2018

Clinical and Experimental Dental Research, Volume 12, Issue 3, June 2026.
ABSTRACT Objectives The relationship between tooth loss and glycemic control status in diabetes is inconclusive. Material and Methods Using data from the 2014–2018 Korean National Health and Nutrition Examination Survey (KNHANES), 2146 adults with diabetes aged ≥ 40 years were categorized by number of remaining teeth (0–19, 20–27, and ≥ 28 ...
Eun Sik Lee, Gyu Bae Lee, Yusun Her, Koh Eun Shin, Kyung‐Hwan Cho, Kyungdo Han, Nai‐Wen Chang, Youngjun Lee, Byoungduck Han, Yang‐Hyun Kim   +9 more
wiley   +1 more source

Tardive Oropharyngeal Dyskinesia Associated With Antipsychotic Use in the Management of Behavioral and Psychological Symptoms of Dementia. [PDF]

J Med Cases
Zohari Z, Obet N, Mohd Zambri NH, Nadarajah R, Tunku Jaafar DTMS.   +4 more
europepmc   +1 more source

Clinical outcomes of mitochondrial‐enhancing nutraceutical supplementation in psychiatric disorders: A systematic review

General Psychiatry, Volume 39, Issue 3, June 2026.
ABSTRACT Background Nutraceutical supplementation targeting mitochondrial function has been proposed as a beneficial therapeutic strategy to improve physical and mental health in psychiatric patients. Aims To summarise the results of studies evaluating nutraceutical supplementation targeting mitochondrial function in patients with psychiatric disorders.
Juan Tortajada, Bengisu Kevser Bulduk, Belén Alfonso‐Landete, Paula Alcaide‐Barriga, Bernat Ballvé‐Gelonch, Glòria Garrabou, Elisabet Vilella, Yolanda Alonso, Alba Valiente‐Pallejà, Lourdes Martorell   +9 more
wiley   +1 more source