Atypical antipsychotics in bipolar disorder: systematic review of randomised trials
BMC Psychiatry, 2007 Background Atypical antipsychotics are increasingly used for treatment of mental illnesses like schizophrenia and bipolar disorder, and considered to have fewer extrapyramidal effects than older antipsychotics.
Moore R Andrew, Derry Sheena
doaj +1 more source
An in vivo biosensor for neurotransmitter release and in situ receptor activity. [PDF]
, 2010 Tools from molecular biology, combined with in vivo optical imaging techniques, provide new mechanisms for noninvasively observing brain processes. Current approaches primarily probe cell-based variables, such as cytosolic calcium or membrane potential ...
Griesbeck, Oliver +6 more
core +2 more sources
Pharmacogenomics of Major Depressive Disorder in Indigenous Amazonian Populations
Clinical Pharmacology &Therapeutics, EarlyView.Major depressive disorder is a highly prevalent psychological disorder worldwide and its main treatment is the use of Selective Serotonin Reuptake Inhibitors. However, few studies have demonstrated the relationship between the presence of genetic variants in pharmacogenes and the efficacy of these drugs, especially in populations with a unique genetic ...
Kaio Evandro Cardoso Aguiar +9 more
wiley +1 more source
Attitudes of European physicians towards the use of long-acting injectable antipsychotics
BMC Psychiatry, 2020 Background Prescription rates for long-acting injectable (LAI) antipsychotic formulations remain relatively low in Europe despite improved adherence over alternative oral antipsychotic treatments.
Maxine X. Patel +6 more
doaj +1 more source
Treatment decision-making capacity in children and adolescents hospitalized for an acute mental disorder: The role of cognitive functioning and psychiatric symptoms [PDF]
, 2017 OBJECTIVE: This study was conducted to assess treatment decision-making capacity (TDMC) in a child and adolescent psychiatric sample and to verify possible associations between TDMC, psychiatric symptom severity, and cognitive functioning.
Ferracuti, Stefano +5 more
core +1 more source
Paediatric developmental safety and the ICH E11A extrapolation of safety
British Journal of Clinical Pharmacology, EarlyView.
Gilbert J. Burckart +6 more
wiley +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.Maternal health remains a critical global concern, particularly in underserved populations and in low‐ and middle‐income countries where access to safe and effective therapeutics is limited. Despite the use of medications by most women during pregnancy, the exclusion of pregnant and lactating women from clinical trials has resulted in significant data ...
Rachel K. Scott +7 more
wiley +1 more source
A comparison of depot and oral atypical antipsychotics in terms of metabolic syndrome markers
Psychiatry and Clinical Psychopharmacology, 2018 OBJECTIVES: The duration of life of patients with schizophrenia is shorter than that of the general population for various reasons. Especially cardiovascular diseases are one of the most important causes of death in patients with schizophrenia.
Demet Sağlam Aykut +1 more
doaj +1 more source
Mechanisms of development of antipsychotic-induced metabolic disorders: pharmacogenetic aspect
Бюллетень сибирской медицины, 2018 Antipsychotics are the main drug group in the treatment of disorders of the schizophrenic spectrum. At the same time, this drug group requires long-term use, has a narrow therapeutic breadth and a large spectrum and high severity of undesirable drug ...
R. F. Nasyrova +4 more
doaj +1 more source
Long-term lithium treatment in bipolar disorder. effects on glomerular filtration rate and other metabolic parameters [PDF]
, 2017 .BACKGROUND: Concerns about potential adverse effects of long-term exposure to lithium as a mood-stabilizing treatment notably include altered renal function.
Abramowicz, Maria +26 more
core +3 more sources