Results 31 to 40 of about 243,764 (341)
Second-Generation Antipsychotics and Dysregulation of Glucose Metabolism: Beyond Weight Gain
Cells, 2019 Second-generation antipsychotics (SGAs) are the cornerstone of treatment for schizophrenia because of their high clinical efficacy. However, SGA treatment is associated with severe metabolic alterations and body weight gain, which can increase the risk ...
Diana Grajales +2 more
semanticscholar +1 more source
BMJ Open, 2021 Objectives To determine the association of long-term use of antipsychotics with the risk of dyslipidaemia.Design A hospital-based cohort study.Setting Electronic health record data of adult mental health inpatients in all 19 specialised psychiatric ...
Juan Li +8 more
doaj +1 more source
Altered brainstem responses to modafinil in schizophrenia: implications for adjunctive treatment of cognition. [PDF]
, 2018 Candidate pro-cognitive drugs for schizophrenia targeting several neurochemical systems have consistently failed to demonstrate robust efficacy. It remains untested whether concurrent antipsychotic medications exert pharmacodynamic interactions that ...
Carter, Cameron S +3 more
core +3 more sources
BMJ Mental Health, 2023 Background The association between antipsychotics and cardiovascular diseases (CVDs) remains significant yet unestablished, especially in Chinese populations.Objective To investigate the risk of CVDs associated with antipsychotics among Chinese ...
Peng Peng +7 more
doaj +1 more source
The acute efficacy of antipsychotics in schizophrenia: a review of recent meta-analyses
Therapeutic Advances in Psychopharmacology, 2018 Schizophrenia is the eighth leading cause of disability worldwide in people aged 15–44 years. Before antidopaminergic antipsychotics were introduced in the 1950s, no effective medications existed for the treatment of schizophrenia. This review summarizes
P. Haddad, C. Correll
semanticscholar +1 more source
Antipsychotics for treatment of delirium in hospitalised non-ICU patients.
Cochrane Database of Systematic Reviews, 2018 BACKGROUND Guidelines suggest limited and cautious use of antipsychotics for treatment of delirium where nonpharmacological interventions have failed and symptoms remain distressing or dangerous, or both.
L. Burry +8 more
semanticscholar +1 more source
Drug-induced liver injury in association with antipsychotics
European Psychiatry, 2022 Introduction Drug-induced liver injury is one of the leading causes for acute liver failure and drug withdrawal after marketing approval. One important risk factor is the extent of exposure of the hepatocytes to a substance, either by high doses or by ...
R. Zeiss, M. Gahr
doaj +1 more source
Dosing strategies for switching from oral risperidone to paliperidone palmitate: Effects on clinical outcomes. [PDF]
, 2017 IntroductionThere are currently no guidelines for switching patients from oral risperidone to paliperidone palmitate (Invega Sustenna®). Furthermore, the paliperidone long-acting injectable (LAI) package insert does not recommend bridging with oral ...
Hsia, Stephanie L +4 more
core +2 more sources
Challenges and pitfalls of antipsychotic prescribing in people with learning disability [PDF]
, 2017 No abstract ...
Alexander, Regi T. +7 more
core +1 more source
Antipsychotics, Metabolic Adverse Effects, and Cognitive Function in Schizophrenia
Frontiers in Psychiatry, 2018 Cognitive impairment is a core symptom domain of schizophrenia. The effect of antipsychotics, the cornerstone of treatment in schizophrenia, on this domain is not fully clear.
Nicole Mackenzie +11 more
semanticscholar +1 more source