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Rational antipsychotic polypharmacy in psychotic and bipolar disorders: A focus on D2 receptor partial agonists [PDF]
Mental Health ClinicianAripiprazole, brexpiprazole, and cariprazine have a unique pharmacology as demonstrated by their high affinity to the dopamine type-2 receptor (ie, D2 receptor).
Aaron Salwan, PharmD, MPH, BCPP
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Negative and Cognitive Symptoms of Schizophrenia: Are there Adequate Pharmacological Treatments?
European Psychiatry, 2022 Introduction The ongoing debate regarding the treatment efficacy for negative and cognitive symptoms in schizophrenia is a subject of continuous frustration among psychiatrists.
O. Vasiliu
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The Effects of Antipsychotics in Experimental Models of Krabbe Disease
Biomedicines, 2023 The role of altered myelin in the onset and development of schizophrenia and changes in myelin due to antipsychotics remains unclear. Antipsychotics are D2 receptor antagonists, yet D2 receptor agonists increase oligodendrocyte progenitor numbers and ...
Kapil Sharma, Kumlesh K. Dev
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Clinically Relevant Interactions between Atypical Antipsychotics and Anti-Infective Agents
Pharmaceuticals, 2020 This is a comprehensive review of the literature on drug interactions (DIs) between atypical antipsychotics and anti-infective agents that focuses on those DIs with the potential to be clinically relevant and classifies them as pharmacokinetic (PK) or ...
Edoardo Spina +3 more
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Next-generation antipsychotics- Trends and perspectives beyond dopaminergic and glutamatergic agents
European Psychiatry, 2023 Introduction Three generations of antipsychotics, all of which are based on the dopaminergic hypothesis of schizophrenia, are available for clinical use.
O. Vasiliu +12 more
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Neurologijos seminarai, 2020 Introduction. Tardive dyskinesia is a movement disorder that begins with exposure to dopamine receptor-blocking agents for at least a few months. These agents include most of antipsychotics, which are widely used to treat mental illness.
I. Pabarčiūtė , M. Karnickas
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Neuroleptic malignant syndrome: a diagnostic dilemma in an unconscious patient—a case report
Ain Shams Journal of Anesthesiology, 2022 Background Neuroleptic malignant syndrome is a clinical condition which has been studied and described well. But history of the patient and the medications he is on are very important to make this diagnosis.
Swati Jain, Shruti Jain, Vandana Talwar
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Thrombotic complications of treatment with antipsychotic drugs : risk factors
European Psychiatry, 2023 Introduction Antipsychotic agents (AP) are widely used drugs to treat psychotic symptoms. For decades, some studies suggested that there is a relationship between using (AP) and the risk of venous thromboembolism (VTE) and pulmonary embolism (PE).
W. Abid +7 more
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Frontiers in Psychiatry, 2023 Exploring the possible correlations between gene variations and the clinical effects of the new-generation antipsychotics is considered essential in the framework of personalized medicine.
Octavian Vasiliu
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Symptomatic treatment of children with anti-NMDAR encephalitis. [PDF]
, 2016 AIM: We performed the first study on the perceived benefit and adverse effects of symptomatic management in children with anti-N-methyl-d-aspartate receptor (NMDAR) encephalitis.
Brilot, F +7 more
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