Analysis of multiply spliced transcripts in lymphoid tissue reservoirs of rhesus macaques infected with RT-SHIV during HAART. [PDF]
Highly active antiretroviral therapy (HAART) can reduce levels of human immunodeficiency virus type 1 (HIV-1) to undetectable levels in infected individuals, but the virus is not eradicated.
Adamson, Lourdes +8 more
core +18 more sources
Exploring the impact of baseline and on-treatment variables on durability of responses to fostemsavir through weeks 96 and 192 in the phase 3 BRIGHTE study. [PDF]
Abstract Objectives The gp120‐directed attachment inhibitor fostemsavir was effective in people with multidrug‐resistant (MDR) HIV‐1 in the BRIGHTE study. Understanding factors associated with virologic response can help clinicians optimize treatment and identify individuals for fostemsavir‐based regimens.
Gartland M +8 more
europepmc +2 more sources
Highly Active Antiretroviral Therapy (HAART) [PDF]
Highly active antiretroviral therapy (HAART) is a treatment strategy for HIV (human immunodeficiency virus)-infected patients that consists of administering three or more different drugs, including nucleoside reverse transcriptase inhibitors, protease inhibitors, and non-nucleoside reverse transcriptase inhibitors.
Daniel Thomas Ginat +1 more
openaire +3 more sources
Effectiveness of highly active antiretroviral therapy in HIV-positive children: evaluation at 12 months in a routine program in Cambodia. [PDF]
OBJECTIVE: Increasing access to highly active antiretroviral therapy to reach all those in need in developing countries (scale up) is slowly expanding to HIV-positive children, but documented experience remains limited. We aimed to describe the clinical,
Akao, K +9 more
core +2 more sources
Highly active antiretroviral therapy [PDF]
The barriers to providing highly active antiretroviral therapy (HAART) in poor countries have until recently seemed insurmountable. The cited problems have ranged from weak health systems and poor infrastructure to inadequate numbers of health professionals. In reality, the main barrier has been the very high cost of antiretroviral drugs.
openaire +2 more sources
Drug resistance and viral tropism in HIV-1 subtype C-infected patients in KwaZulu-Natal, South Africa: implications for future treatment options [PDF]
Article approval pendingDrug resistance poses a significant challenge for the successful application of highly active antiretroviral therapy (HAART) globally. Furthermore, emergence of HIV-1 isolates that preferentially use CXCR4 as a coreceptor for cell
Ashika Singh +48 more
core +2 more sources
Panhypopituitarism in HIV patient receiving antiretroviral therapy
The article is dedicated to a clinical case of the panhypopituitarism development in a patient with HIV infection receiving antiretroviral therapy. The number of HIV-infected patients worldwide has increased significantly over the past decades.
Tatyana B. Morgunova +5 more
doaj +1 more source
Directly observed antiretroviral therapy: a systematic review and meta-analysis of randomised clinical trials. [PDF]
BACKGROUND: Directly observed therapy has been recommended to improve adherence for patients with HIV infection who are on highly active antiretroviral therapy, but the benefit and cost-effectiveness of this approach has not been established conclusively.
Altice +41 more
core +3 more sources
Effect of HIV infection and antiretroviral therapy on hepatitis B virus (HBV)-specific T cell responses in patients who have resolved HBV infection [PDF]
Coinfection with hepatitis B virus (HBV) is a common occurrence in human immunodeficiency virus (HIV)–positive patients and an increasing cause of morbidity and mortality.
Bertoletti, A. +9 more
core +1 more source
Deciphering the Presence of Active Interscapular Brown Adipose Tissue in Humans. [PDF]
ABSTRACT Brown adipose tissue (BAT) is increasingly recognized as a metabolically active tissue in humans, although its physiological relevance remains incompletely understood. In rodents, BAT is well characterized, with interscapular BAT (iBAT) representing the main thermogenic depot.
Sanchez-Gomez J +8 more
europepmc +2 more sources

