Results 61 to 70 of about 8,379,610 (258)

Lipodystrophy and metabolic parameters of people living with HIV

DST, 2018
Introduction: Since the earliest reported cases in the United States, Acquired Immunodeficiency Syndrome (AIDS) remains one of the major challenges to global health.
Labibe do Socorro Haber de Menezes, Khayro Lima dos Reis, Michel Douglas Silva de Sousa, Diego de Aviz Gonçalves, Manfried Cleiton Mendes Rocha, Rosana Maria Feio Libonati   +5 more
doaj  

Pharmacokinetic Assessment of Atazanavir and Favipiravir Following Echinacea Supplementation: A Controlled Herb–Drug Interaction Investigation

Biopharmaceutics &Drug Disposition, EarlyView.
Pharmacokinetic interactions between Echinacea and two antiviral drugs, favipiravir and atazanavir, were assessed in rats. The findings suggest that Echinacea does not significantly affect the pharmacokinetics of favipiravir and atazanavir. These results provide preliminary evidence that concurrent use of Echinacea with these antiviral drugs may be ...
Siva Nageswara Rao Gajula, Jeevan Sai Kallam, Aarika Kanukolanu, Ganesh Korada, Lakshmi Vineela Nalla   +4 more
wiley   +1 more source

Treatment exhaustion of highly active antiretroviral therapy (HAART) among individuals infected with HIV in the United Kingdom: multicentre cohort study [PDF]

, 2005
Objectives To investigate whether there is evidence that an increasing proportion of HIV infected patients is starting to experience increases in viral load and decreases in CD4 cell count that are consistent with exhaustion of available treatment ...
Youle, M S, Mike S Youle (16122224), Philippa Easterbrook (70407), UK CHIC Study Grp, Phillips, AN, Sanjay Bhagani (300128), Youle, MS, Scullard, G, Ryanne Matthias (16122221), Richard Gilson (125405), Andrew N Phillips (3559133), Caroline A Sabin (8085905), Hill, T, Teresa Hill (16119995), Martin Fisher (300134), Gazzard, B, Sabin, CA, Brian Gazzard (4921), Lampe, F, Fisher, M, George Scullard (16122227), Phillips, A N, Fiona Lampe (282424), Johnson, MA, Easterbrook, P, Gilson, R, Margaret A Johnson (16120793), Sabin, C A, Bhagani, S, Matthias, R, Johnson, M A   +30 more
core   +1 more source

Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality

BMEMat, EarlyView.
Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim, Marwa Ahmed El‐Naka, Wedad M. Nageeb, Atta Ullah Khan, Noura M. Seleem, Aliaa Abdelghafar, Doaa Zamel, Yang Liu, Qigai He, Wentao Li   +9 more
wiley   +1 more source

Neuropsychiatric profile of a cohort of perinatally infected HIV positive children after one year of antiretroviral medication [PDF]

, 2012
Includes abstract.Includes bibliographical references.The Highly Active Antiretroviral Therapy (HAART) era in the mid-nineties signalled a dramatic change in the long-term outcome of Human Immunodeficiency Virus (HIV).
Nassen, René
core   +1 more source

Cost-effectiveness of tenofovir instead of zidovudine for use in first-line antiretroviral therapy in settings without virological monitoring. [PDF]

, 2012
BACKGROUND: The most recent World Health Organization (WHO) antiretroviral treatment guidelines recommend the inclusion of zidovudine (ZDV) or tenofovir (TDF) in first-line therapy.
Phillips, AN, Alec Miners, Valentina Cambiano (146513), von Wyl Viktor, Phillips, Andrew N, Andrew N Phillips, Bertagnolio, S, Cambiano, V, Jens Lundgren, Valentina Cambiano, Silvia Bertagnolio, Pillay Deenan, Pillay, Deenan, Deenan Pillay (7888), Bertagnolio, Silvia, Miners Alec, Jordan, MR, Michael R. Jordan (146520), Cambiano, Valentina, von Wyl, Viktor, Viktor von Wyl, Phillips Andrew N., Jordan, Michael R, Cambiano Valentina, Miners, Alec, Pillay, D, Bertagnolio Silvia, Lundgren Jens, Miners, A, Andrew N. Phillips (146556), Lundgren, Jens, Alec Miners (146534), Viktor von Wyl (146506), Silvia Bertagnolio (57174), Michael R Jordan, Deenan Pillay, von Wyl, V, Lundgren, J, Jens Lundgren (146550), Jordan Michael R.   +39 more
core   +2 more sources

Immune Reconstitution Syndrome with Initiation of Treatment of HBV/HIV Co-infection: Activity Flare associated with E antigen Seroconversion

Annals of Hepatology, 2019
Immune reconstitution syndrome is a recognized complication with initiation of highly active antiretroviral therapy for acquired immune deficiency syndrome patients co-infected with hepatitis B.
Michael W. Rowley, Amitkumar Patel, Wendi Zhou, Mark Wong, Anil B. Seetharam   +4 more
doaj   +1 more source

Long‐Acting Therapeutics in Pediatric Health: Bridging Innovation and Access

Clinical Pharmacology &Therapeutics, EarlyView.
Children have distinct therapeutic needs arising from age‐dependent physiology, disease epidemiology, formulation requirements, dosing considerations, and safety vulnerabilities. Despite substantial reductions in childhood mortality over the past three decades, nearly 5 million children under five died in 2023, with infectious diseases continuing to ...
Prajith Venkatasubramanian, Moherndran Archary, Daniel B. Hawcutt, Rachel Daley, Edmund Capparelli, Adeniyi Olagunju   +5 more
wiley   +1 more source

Effect of HIV infection and antiretroviral therapy on hepatitis B virus (HBV)-specific T cell responses in patients who have resolved HBV infection [PDF]

, 2005
Coinfection with hepatitis B virus (HBV) is a common occurrence in human immunodeficiency virus (HIV)–positive patients and an increasing cause of morbidity and mortality.
Dunn, C., Maini, M.K., Copas, A., Gilson, R.J., Lascar, R.M., Johnstone, R., Bertoletti, A., Webster, G., Lopes, A.R., Reignat, S.   +9 more
core  

Comparison of the effectiveness of initial combined antiretroviral therapy with nelfinavir or efavirenz at a university-based outpatient service in Brazil

Brazilian Journal of Medical and Biological Research, 2007
Since there are some concerns about the effectiveness of highly active antiretroviral therapy in developing countries, we compared the initial combination antiretroviral therapy with zidovudine and lamivudine plus either nelfinavir or efavirenz at a ...
T. Vanni, K.M. Morejón, R.C. Santana, L. de Melo, S.B.R.L. Ferrão, A.P. Amorim, G.G. Gaspar, C.C. Ponzi, N.A. Golin, F.L. Custódio, A.T.D. Marangoni, C.P. Campos Jr., B.A.L. Fonseca   +12 more
doaj   +1 more source