Results 101 to 110 of about 174,855 (309)

Individualization of antiretroviral therapy

, 2012
Antiretroviral therapy (ART) has evolved considerably over the last three decades. From the early days of monotherapy with high toxicities and pill burdens, through to larger pill burdens and more potent combination therapies, and finally, from 2005 and ...
Pavlos, R., Phillips, E.J.
core  

The Expanding Role of Companion Diagnostics in Infectious Diseases: Lessons From Abacavir and Human Immunodeficiency Virus Care

iLABMED, EarlyView.
Yi‐Wei Tang, Eric von Hofe
wiley   +1 more source

Beyond Standard Half‐Life: Real‐world Pharmacokinetics of Efanesoctocog Alfa in a Single Centre

Haemophilia, EarlyView.
ABSTRACT Introduction Efanesoctocog alfa (EFA) is an ultra–extended half‐life factor VIII (FVIII) developed to address limitations of conventional prophylaxis in haemophilia A. Although the XTEND trials reported low interindividual pharmacokinetic (PK) variability, real‐world data remain important to better characterize PK profiles across patient ...
Laurent Sattler, Agathe Herb, Léa Pierre, Jordan Wimmer, Manon Dolt, Olivier Feugeas, Dominique Desprez   +6 more
wiley   +1 more source

The Impact of Antiretroviral Therapy on Mortality in HIV Positive People during Tuberculosis Treatment: A Systematic Review and Meta-Analysis [PDF]

, 2014
Objective: To quantify the impact of antiretroviral therapy (ART) on mortality in HIV-positive people during tuberculosis (TB) treatment. Design: We conducted a systematic literature review and meta-analysis.
Grant, Alison D, Alison D Grant, Richard G White, Houben, Rein M. G. J., Rein M G J Houben, Silvia Amadasi (659206), Amadasi, Silvia, Richard G. White (92065), Alison D. Grant (143327), Houben, Rein MGJ, Silvia Amadasi, White, Richard G, Rein M. G. J. Houben (339509), Grant, Alison D., White, Richard G., Theodore Cohen (659207), Theodore Cohen, Odone, Anna, Cohen, Theodore, Anna Odone, Anna Odone (474858)   +20 more
core   +1 more source

Scaling HIV self‐testing to improve health equity among cisgender gay, bisexual and other men who have sex with men, trans and gender‐diverse people in the United Kingdom: An HIV self‐testing implementation action framework

HIV Medicine, EarlyView.
Abstract Background HIV self‐testing (HIVST) is feasible, highly acceptable and can increase HIV testing uptake/frequency without harm while also reducing costs. Despite HIVST's benefits, UK service provision has been sporadic partially due to policymakers and commissioners' reluctance over concerns about linkage to care/surveillance, which ultimately ...
T. Charles Witzel, Peter Weatherburn, Fiona M. Burns, Isaac Y.‐H. Chu, Phil Samba, Alison J. Rodger   +5 more
wiley   +1 more source

A multidisciplinary, AI‐supported quality improvement intervention to manage polypharmacy in aging people with HIV

HIV Medicine, EarlyView.
Abstract Objectives Aging people with HIV are increasingly affected by multimorbidity and polypharmacy, which heighten the risk of drug–drug interactions (DDIs) and potentially inappropriate medications (PIMs). This study evaluated a multidisciplinary, AI‐supported quality improvement intervention designed to optimize polypharmacy management in older ...
Jovana Milic, Antonia Pugliese, Michela Belli, Gian Luca Lonardi, Caterina Ruffilli, Tommaso Albano, Marco Visicaro, Martina Ricciardetto, Pierluigi De Cosmo, Chiara Mussi, Francesca Gandolfi, Cristina Mussini, Costantino Grana, Giovanni Guaraldi   +13 more
wiley   +1 more source

Magnitude of adverse drug reaction and associated factors among HIV-infected adults on antiretroviral therapy in Hiwot Fana specialized university hospital, eastern Ethiopia

The Pan African Medical Journal, 2016
INTRODUCTION: human immunodefiecency virus infected patients did not adhere correctly to their Antiretroviral Therapy because it?s adverse effects.
Fitsum Weldegebreal, Habtamu Mitiku, Zelalem Teklemariam   +2 more
doaj   +1 more source

Pregnancy is associated with elevation of liver enzymes in HIV-positive women on antiretroviral therapy.

, 2015
The objective of this study is to assess whether pregnancy is associated with an increased risk of liver enzyme elevation (LEE) and severe LEE in HIV-positive women on antiretroviral therapy (ART)
the UK Collaborative HIV Cohort (UK CHIC) Study, the UK, Ireland National Study of HIV in Pregnancy, Childhood (NSHPC),, Sabin, C, Thorne, C, Pillay, D, Huntington, S, Tookey, PA, Newell, ML, Taylor, GP, Anderson, J, Hill, T   +9 more
core  

Linkage to HIV care and antiretroviral therapy in Cape Town, South Africa. [PDF]

, 2010
BACKGROUND: Antiretroviral therapy (ART) has been scaled-up rapidly in Africa. Programme reports typically focus on loss to follow-up and mortality among patients receiving ART.
Zeinecker, Jennifer, Zeinecker Jennifer, Philip Ginsberg, Kalawe, Nosindiso N, Lawn, Stephen D, Robin Wood, Stephen D Lawn, Ginsberg Philip, Bekker Linda-Gail, Kranzer Katharina, Orrell, Catherine, Orrell Catherine, Lawn Stephen D., Nosindiso N. Kalawe, Ginsberg, Philip, Stephen D. Lawn, Katharina Kranzer, Nosindiso N Kalawe, Linda-Gail Bekker, Kalawe Nosindiso N., Wood Robin, Bekker, Linda-Gail, Kranzer, Katharina, Jennifer Zeinecker, Catherine Orrell, Wood, Robin   +25 more
core   +1 more source

HIV‐1 viral load and reservoir size remain stable following SARS‐CoV‐2 mRNA vaccination in people with HIV

HIV Medicine, EarlyView.
Abstract Background The potent immunogenicity of mRNA vaccination raised concerns about its impact on HIV‐1 viral load (VL) and reservoir size in people with HIV, which could drive vaccine hesitancy. As part of a prospective clinical trial, we investigated whether SARS‐CoV‐2 mRNA vaccination induced changes in VL and reservoir size after a 1‐year three‐
Oscar Kieri, Bianca B Jütte, Jan Vesterbacka, Soo Aleman, Hans‐Gustaf Ljunggren, Marcus Buggert, J Peter Svensson, Anders Sönnerborg, Piotr Nowak   +8 more
wiley   +1 more source