Effectiveness of antiretroviral therapy in the single-tablet regimen era
OBJECTIVE To evaluate the effectiveness of antiretroviral therapy and the associated factors according to the type of regimen used: Single Tablet Regimen or Multiple Tablet Regimen.
Juliana de Oliveira Costa +5 more
doaj +1 more source
Switching to second-line antiretroviral therapy in resource-limited settings: comparison of programmes with and without viral load monitoring. [PDF]
In high-income countries, viral load is routinely measured to detect failure of antiretroviral therapy (ART) and guide switching to second-line ART. Viral load monitoring is not generally available in resource-limited settings. We examined switching from
Boulle, A +18 more
core +4 more sources
Affinity Proteomics‐Based Non‐Invasive Detection of Clinically Significant Liver Disease
Using UK Biobank proteomic data, we identified a five‐protein score reflecting hepatic stellate cell activation and hepatocellular injury that predicts major adverse liver outcomes and clinically significant fibrosis, with consistent performance validated in two independent cohorts (patients with HIV and alpha1‐antitrypsin deficiency).
Sriram Balasubramani +14 more
wiley +1 more source
Brain viral reservoirs were undetectable in neonatal SIV during the first 3 days post infection; antiretroviral therapy (ART) at 3 dpi prevented brain reservoir seeding and normalized metabolic function, highlighting the necessity of very early treatment to protect the developing CNS.
Li Ma +12 more
wiley +1 more source
Initiation of antiretroviral therapy
With the widespread availability of antiretroviral therapy, there is a dramatic decline in HIV related morbidity and mortality in both developed and developing countries. Further, the current antiretroviral drug combinations are safer and the availability of newer monitoring assays and guidelines has vastly improved the patient management.
Pandhi, Deepika, Ailawadi, Pallavi
openaire +3 more sources
How Much Does It Cost to Provide Antiretroviral Therapy for HIV/AIDS in Africa? [PDF]
Background: Many African countries are rapidly expanding HIV/AIDS treatment programs. Empirical information on the cost of delivering antiretroviral therapy (ART) for HIV/AIDS is needed for program planning and budgeting.
Long, Lawrence, Rosen, Sydney
core +1 more source
HPV42 – a human papillomavirus classified as a low‐risk type with oncogenic potential
Summary Human papillomavirus (HPV) type 42 is a rare HPV type currently classified as “low‐risk” and belongs to the alpha genus. It has primarily been detected in benign vulvar papillomas and is predominantly associated with benign lesions such as anogenital warts.
Sven Niklas Burmann +7 more
wiley +1 more source
Retention on antiretroviral therapy in low- and middle-income countries: systematic review of papers and abstracts since 2008 [PDF]
This repository item contains a single issue of the Health and Development Discussion Papers, an informal working paper series that began publishing in 2002 by the Boston University Center for Global Health and Development.
Fox, Matthew, Rosen, Sydney
core +1 more source
Benefit of viral load testing for confirmation of immunological failure in HIV patients treated in rural Malawi. [PDF]
Objective Viral load testing is used in the HIV programme of Chiradzulu, Malawi, to confirm the diagnosis of immunological failure to prevent unnecessary switching to second-line therapy.
Badri +14 more
core +2 more sources

