Results 121 to 130 of about 4,576,038 (327)

The Complex Nature of Adherence in the Management of HIV/AIDS as a Chronic Medical Condition

Diseases, 2013
The introduction of antiretroviral therapy (ART) in the management of HIV infection has resulted in a significant reduction in the morbidity and mortality associated with the disease.
Adegoke O. Adefolalu, Zerish Z. Nkosi
doaj   +1 more source

Post-Treatment HIV-1 Controllers with a Long-Term Virological Remission after the Interruption of Early Initiated Antiretroviral Therapy ANRS VISCONTI Study

PLoS Pathogens, 2013
Combination antiretroviral therapy (cART) reduces HIV-associated morbidities and mortalities but cannot cure the infection. Given the difficulty of eradicating HIV-1, a functional cure for HIV-infected patients appears to be a more reachable short-term ...
A. Sáez-Cirión, C. Bacchus, L. Hocqueloux, V. Avettand-Fenoel, I. Girault, C. Lécuroux, V. Potard, P. Versmisse, A. Mélard, T. Prazuck, B. Descours, J. Guergnon, J. Viard, F. Boufassa, O. Lambotte, C. Goujard, L. Meyer, D. Costagliola, A. Venet, G. Pancino, B. Autran, C. Rouzioux   +21 more
semanticscholar   +1 more source

CRISPR Technology in Disease Management: An Updated Review of Clinical Translation and Therapeutic Potential

Cell Proliferation, EarlyView.
CRISPR‐Cas systems offer transformative genome editing capabilities for precise manipulation of cellular genes. This enables two main therapeutic avenues: ex vivo modification of patient cells for re‐transplantation or direct in vivo gene targeting via advanced delivery methods.
Bahareh Farasati Far, Marziyeh Akbari, Mohammad Amin Habibi, Morteza Katavand, Sherko Nasseri   +4 more
wiley   +1 more source

Trichophyton mentagrophytes type VII: cohort study on patient characteristics, clinical features, disease course, and treatment

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and Objectives Sexually transmitted infections with Trichophyton mentagrophytes type VII (TMVII) have been reported in several countries. The aim of our study was to identify epidemiological and clinical features in order to improve prevention, diagnosis, and treatment.
Konstanze Kämmerer, Julia Huynh, Cornelia Deutsch, Stefanie May, Sertac Uyar, Alexander Nast, Christoph Zeyen, Ricardo Niklas Werner   +7 more
wiley   +1 more source

Combined antineoplastic and antiretroviral therapy for patients with hodgkin's disease and human immunodeficiency virus infection. A prospective study of 17 patients [PDF]

, 1994
D. Errante, Umberto Tirelli, Roberta Gastaldi, D. Milo, Anna Maria Nosari, Giuseppe Rossi, Giammaria Fiorentini, Antonino Carbone, Emanuela Vaccher, S. Monfardini   +9 more
openalex   +1 more source

Treatment with indinavir, zidovudine, and lamivudine in adults with human immunodeficiency virus infection and prior antiretroviral therapy.

New England Journal of Medicine, 1997
BACKGROUND The new protease inhibitors are potent inhibitors of the human immunodeficiency virus (HIV), and in combination with other antiretroviral drugs they may be able to cause profound and sustained suppression of HIV replication.
R. Gulick, J. Mellors, D. Havlir, J. Eron, C. J. González, D. McMahon, D. Richman, F. Valentine, L. Jonas, A. Meibohm, E. Emini, J. Chodakewitz   +11 more
semanticscholar   +1 more source

The role of nevirapine in the antiretroviral therapy

HIV & AIDS Review, 2008
Summary In the presented multicenter study an attempt was made to evaluate the role of nevirapine used in treatment of HIV-seropositive patients in both groups: naive as well as experienced. The therapeutic effect was evaluated while analysing the HIV-RNA level and the increase in CD4 cell count.
Lemańska, Małgorzata, Jankowska, Maria, Cielniak, I., Witor, A., Szetela, B., Leszczyszyn-Pynka, M., Wnuk, A., Wiercińska-Drapało, A., Olczak, A., Małolepsza, E., Jabłonowska, E., Barałkiewicz, G., Skwara, P., Mian, M., Mikuła, T.   +14 more
openaire   +2 more sources

Combined screening of human immunodeficiency virus, hepatitis B virus, and hepatitis C virus in an emergency department: The URDEPTRIO cross‐sectional study

Academic Emergency Medicine, EarlyView.
Chris Wong, Quentin Le Hingrat, Florian Salipante, Vincent Mackiewicz, Florence Damond, Lucile Larrouy, Christophe Choquet, Dan Pospai, Karen Champenois, Diane Descamps, Judith Leblanc, Paul Loubet, Enrique Casalino, Jade Ghosn, Donia Bouzid   +14 more
wiley   +1 more source

Spinal Stenosis: An Emerging Complication of Ageing in People With Haemophilia

Haemophilia, EarlyView.
ABSTRACT Introduction Advances in haemophilia care have brought the challenges of ageing for people with haemophilia (PWH) to the forefront. Age‐related spinal degeneration may result in spinal stenosis; however, the rates in PWH are unknown. We sought to systematically review Irish PWH to address this gap in the current literature.
Claire Kelly, Mark McGowan, Niamh Larkin, Jake M. Mc Donnell, Anne‐Marije Hilshof, Mary Byrne, Catherine Bergin, Aine O'Gara, Kevin Ryan, Mairead O'Donovan, Niamh O'Connell, Keith Synnott, Joseph S. Butler, Stacey Darwish, Brian O'Mahony, Megan Kennedy, Peter L. Turecek, James S. O'Donnell, John Gormley, Michelle Lavin   +19 more
wiley   +1 more source

Health benefits, costs, and cost-effectiveness of earlier eligibility for adult antiretroviral therapy and expanded treatment coverage: a combined analysis of 12 mathematical models

The Lancet Global Health, 2014
Background: New WHO guidelines recommend initiation of antiretroviral therapy for HIV-positive adults with CD4 counts of 500 cells per μL or less, a higher threshold than was previously recommended.
Jeffrey W Eaton, PhD, Nicolas A Menzies, MPH, John Stover, MA, Valentina Cambiano, MS, Leonid Chindelevitch, PhD, Anne Cori, PhD, Jan A C Hontelez, PhD, Salal Humair, PhD, Cliff C Kerr, PhD, Daniel J Klein, PhD, Sharmistha Mishra, MD, Kate M Mitchell, PhD, Brooke E Nichols, MS, Prof. Peter Vickerman, DPhil, Roel Bakker, PhD, Till Bärnighausen, DSc, Anna Bershteyn, PhD, Prof. David E Bloom, PhD, Marie-Claude Boily, PhD, Stewart T Chang, PhD, Ted Cohen, DPH, Peter J Dodd, PhD, Prof. Christophe Fraser, PhD, Chaitra Gopalappa, PhD, Prof. Jens Lundgren, DMSc, Natasha K Martin, DPhil, Evelinn Mikkelsen, MSc, Elisa Mountain, MSc, Quang D Pham, MD, Michael Pickles, PhD, Prof. Andrew Phillips, PhD, Lucy Platt, PhD, Carel Pretorius, PhD, Holly J Prudden, MSc, Prof. Joshua A Salomon, PhD, David A M C van de Vijver, PhD, Sake J de Vlas, PhD, Bradley G Wagner, PhD, Richard G White, PhD, David P Wilson, PhD, Lei Zhang, PhD, John Blandford, PhD, Gesine Meyer-Rath, PhD, Michelle Remme, MSc, Paul Revill, PhD, Nalinee Sangrujee, PhD, Fern Terris-Prestholt, PhD, Meg Doherty, PhD, Nathan Shaffer, MD, Prof. Philippa J Easterbrook, MD, Gottfried Hirnschall, MD, Prof. Timothy B Hallett, PhD   +51 more
doaj   +1 more source