Results 11 to 20 of about 141,326 (319)

A cross‐sectional clinical study in women to investigate possible genotoxicity and hematological abnormalities related to the use of black cohosh botanical dietary supplements

Environmental and Molecular Mutagenesis, Volume 63, Issue 8-9, Page 389-399, December 2022., 2022
Abstract Black cohosh (BC; Actaea racemosa L.), a top‐selling botanical dietary supplement, is marketed to women primarily to ameliorate a variety of gynecological symptoms. Due to widespread usage, limited safety information, and sporadic reports of hepatotoxicity, the Division of the National Toxicology Program (DNTP) initially evaluated BC extract ...
Stephanie L. Smith‐Roe, Stavros Garantziotis, Rebecca L. Church, Jeffrey C. Bemis, Dorothea K. Torous, Kim G. Shepard, Cheryl A. Hobbs, Suramya Waidyanatha, Esra Mutlu, Keith R. Shockley, Grace E. Kissling, Sandra J. McBride, Guanhua Xie, Tim Cristy, Jessica Pierfelice, Kristine L. Witt   +15 more
wiley   +1 more source

A graph neural network-based model with Out-of-Distribution Robustness for enhancing Antiretroviral Therapy Outcome Prediction for HIV-1 [PDF]

, 2023
Predicting the outcome of antiretroviral therapies (ART) for HIV-1 is a pressing clinical challenge, especially when the ART includes drugs with limited effectiveness data. This scarcity of data can arise either due to the introduction of a new drug to the market or due to limited use in clinical settings, resulting in clinical dataset with highly ...
arxiv   +1 more source

Incorporating temporal dynamics of mutations to enhance the prediction capability of antiretroviral therapy's outcome for HIV-1 [PDF]

Bioinformatics, Volume 40, Issue 6, June 2024, btae327, 2023
Motivation: In predicting HIV therapy outcomes, a critical clinical question is whether using historical information can enhance predictive capabilities compared with current or latest available data analysis. This study analyses whether historical knowledge, which includes viral mutations detected in all genotypic tests before therapy, their temporal ...
arxiv   +1 more source

Treatment outcomes and costs of a simplified antiretroviral treatment strategy for hepatitis C among Hepatitis C Virus and Human Immuno deficiency Virus co‐infected patients in Ukraine

JGH Open, Volume 6, Issue 12, Page 894-903, December 2022., 2022
We assessed treatment and cost outcomes for integrated HIV and viral hepatitis testing with ledipasvir/sofosbuvir ± weight‐based ribavirin for 12 weeks in Kyiv, Ukraine. Overall, a sustained virological response (SVR) was achieved in 831 of 868 patients (95.7%).
Sergie Antoniak, Charles S Chasela, Morgan Julie Freiman, Yulia Stopolianska, Tetiana Barnard, Malini M Gandhi, Maria Liulchuk, Zhanna Tsenilova, Tretiakov Viktor, Jeri Dible, Constance Wose Kinge, Francis Akpan, Thomas Minior, Ntombi Sigwebela, Sofiane Mohamed, Matthiue Barralon, Fadzai Marange, Clint Cavenaugh, Charles Vander Horst, Svitlana Antonyak, Thembisile Xulu, Kara W Chew, Ian Sanne, Sydney Rosen, for EQUIP Health   +24 more
wiley   +1 more source

Obliterative portal venopathy: A neglected and probably misdiagnosed disease with peculiar etiology in South America

JGH Open, Volume 6, Issue 12, Page 904-909, December 2022., 2022
Classically described in the group of non‐cirrhotic portal hypertension, obliterative portal venopathy (OPV) causes are still unknown. Our aim is to describe the characteristics of 43 OPV patients and potential risk factors. Clinically significant portal hypertension was found in 28% of cases. The most frequent indication for liver biopsy was elevation
Vinícius Nunes, Luiz A R de Freitas, Juliana R de Freitas, Caio Araújo, Gildásio N Junior, Maria I Schinoni, Fernando Bessone, Raymundo Paraná   +7 more
wiley   +1 more source

Role of body mass index in outcomes of patients hospitalized with COVID‐19 illness

Obesity Science &Practice, Volume 8, Issue 6, Page 748-756, December 2022., 2022
Abstract Background Since the start of coronavirus disease 2019 (COVID‐19) pandemic, several studies have linked obesity with severity of illness as well as mortality in patients with COVID‐19. Outcomes of patients with overweight or obesity, who develop critical illness, have been studied extensively over the past decade where the studies have shown ...
Maleeha Zahid, Vivien Leung, Suresh Kumar Nayudu, Sneha Galiveeti, Nikhitha Mantri, Haozhe Sun, Sudharsan Gongati, Vijaya Perugu, Sridhar Chilimuri   +8 more
wiley   +1 more source

Antiretroviral Side Effects on Adherence in People Living with HIV/AIDS

Nurse Media: Journal of Nursing, 2018
Background: Antiretroviral therapy is a lifelong treatment in people living with HIV/AIDS (PLWHA). Adherence is the key to the effectiveness of antiretroviral therapy.
Gede Arya Bagus Arisudhana, Muchlis Achsan Udji Sofro, Untung Sujianto   +2 more
doaj   +1 more source

A case report of clinical implications of a delayed antiretroviral therapy switch in a patient with multiple treatment interruptions

SAGE Open Medical Case Reports, 2022
The Namibia national antiretroviral therapy guidelines recommend that patients living with HIV who interrupt antiretrovirals and in the process disengage from care be restarted on their usual antiretroviral therapy regimen upon return.
Mireille A Mpalang Kakubu, Kandali Frans, Nelson Gibutai, Patrick DMC Katoto   +3 more
doaj   +1 more source

Highly active antiretroviral therapy [PDF]

The Lancet, 1998
DI PERRI, Giovanni, BONORA, Stefano, VENTO S., ALLEGRANZI B., CONCIA E.   +4 more
openaire   +6 more sources

Training needs assessment for clinicians at antiretroviral therapy clinics: evidence from a national survey in Uganda

Human Resources for Health, 2009
Background To increase access to antiretroviral therapy in resource-limited settings, several experts recommend "task shifting" from doctors to clinical officers, nurses and midwives.
Namagala Elizabeth, Lule Frank, Kaye Richard, Sebuyira Lydia, Oyugi Jessica H, Weaver Marcia R, Schneider Gisela, Lutalo Ibrahim M, Scheld W, McAdam Keith PWJ, Sande Merle A   +10 more
doaj   +1 more source