Results 41 to 50 of about 4,800,081 (359)

Patient-Reported Barriers to Adherence to Antiretroviral Therapy: A Systematic Review and Meta-Analysis

PLoS Medicine, 2016
Background Maintaining high levels of adherence to antiretroviral therapy (ART) is a challenge across settings and populations. Understanding the relative importance of different barriers to adherence will help inform the targeting of different ...
Z. Shubber, E. Mills, J. Nachega, R. Vreeman, M. Freitas, P. Bock, S. Nsanzimana, M. Penazzato, Tsitsi Appolo, M. Doherty, N. Ford   +10 more
semanticscholar   +1 more source

Immediate Antiretroviral Therapy Decreases Mortality Among Patients With High CD4 Counts in China: A Nationwide, Retrospective Cohort Study. [PDF]

, 2017
BackgroundClinical trials have demonstrated that immediate initiation of antiretroviral therapy (ART) reduces AIDS-related morbidity and mortality. We tested the hypothesis that initiating ART ≤30 days after human immunodeficiency virus (HIV) diagnosis ...
Brookmeyer, Ron, Detels, Roger, Dou, Zhihui, Li, Aihua, Ma, Ye, McGoogan, Jennifer M, Montaner, Julio SG, Qin, Qianqian, Shi, Cynthia X, Wu, Zunyou, Zhao, Yan   +10 more
core   +1 more source

The Quality of Life of Patients with HIV/AIDS Undergoing Antiretroviral Therapy: A Systematic Review

Jurnal Ners, 2019
Introduction: Quality of Life (QoL) is one of the most important things for a patient with HIV/AIDS. Good QoL will improve the adherence to treatment, especially antiretroviral therapy.
Putri Irwanti Sari, RTS Netisa Martawinarti, Nurmawati S. Lataima, Vivi Meiti Berhimpong   +3 more
doaj   +1 more source

Improving the Adherence to Antiretroviral Therapy, a Difficult but Essential Task for a Successful HIV Treatment—Clinical Points of View and Practical Considerations

Frontiers in Pharmacology, 2017
HIV infection is responsible for one the most devastating human pandemics. The advent of antiretroviral therapy has changed the course of the pandemic and saved millions of lives.
S. Iacob, D. Iacob, G. Jugulete
semanticscholar   +1 more source

Benefits and risks of rapid initiation of antiretroviral therapy

AIDS (London), 2017
Background: Recent attention has focused on the question of how quickly antiretroviral therapy (ART) should be started once HIV diagnosis is confirmed. We assessed whether rapid ART initiation improves patient outcomes.
N. Ford, C. Migone, A. Calmy, B. Kerschberger, S. Kanters, S. Nsanzimana, E. Mills, G. Meintjes, M. Vitoria, M. Doherty, Z. Shubber   +10 more
semanticscholar   +1 more source

ING116070: a study of the pharmacokinetics and antiviral activity of dolutegravir in cerebrospinal fluid in HIV-1-infected, antiretroviral therapy-naive subjects. [PDF]

, 2014
BackgroundDolutegravir (DTG), a once-daily, human immunodeficiency virus type 1 (HIV-1) integrase inhibitor, was evaluated for distribution and antiviral activity in cerebrospinal fluid (CSF).MethodsING116070 is an ongoing, single-arm, open-label ...
Chen, Shuguang, extended ING116070 study team, Letendre, Scott L, Mills, Anthony M, Min, Sherene S, Piscitelli, Stephen C, Song, Ivy H, Tashima, Karen T, Thomas, Deborah A   +8 more
core   +3 more sources

Portable Low‐Field Magnetic Resonance Imaging in People With Human Immunodeficiency Virus

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The aging population of people with HIV (PWH) raises heightened concerns regarding accelerated aging and dementia. Portable, low‐field MRI (LF‐MRI) is an innovative technology that could enhance access and facilitate routine monitoring of PWH.
Annabel Sorby‐Adams, Malachi Keo, Jennifer Guo, Daire Daly, Richard Ahern, Kimon Zachary, Gregory Robbins, Rajesh T. Gandhi, Bragi Sveinsson, Adam de Havenon, Kevin N. Sheth, Otto Rapalino, Juan Eugenio Iglesias Gonzales, W. Taylor Kimberly, Shibani S. Mukerji   +14 more
wiley   +1 more source

At‐Home Early Diagnosis of Mastitis: Calibration‐Free Analysis of Sodium to Potassium Ratio in Breast Milk

Advanced Functional Materials, EarlyView.
MAMAWEL is introduced as the first calibration‐free potentiometric sensor for at‐home mastitis diagnosis. By measuring the sodium‐to‐potassium ratio in breast milk, the device reliably differentiates between healthy and mastitis‐affected samples with less than 10% error.
Ali Soleimani, Farbod Amirghasemi, Melissa Banks, Abdulrahman Al‐Shami, Sina Khazaee Nejad, Abdalrhman Sheer, Clare Dominique Sanchez, Haozheng Ma, Daniel Vargas Ramos, Maral P.S. Mousavi   +9 more
wiley   +1 more source

Incidence rate of modifying or discontinuing first combined antiretroviral therapy regimen due to toxicity during the first year of treatment stratified by age

Brazilian Journal of Infectious Diseases, 2014
Toxicity is the most frequently reported reason for modifying or discontinuing the first combined antiretroviral therapy regimens, and it can cause significant morbidity, poor quality of life and also can be an important barrier to adherence, ultimately ...
Thiago Silva Torres, Sandra Wagner Cardoso, Luciane S. Velasque, Valdilea G. Veloso, Beatriz Grinsztejn   +4 more
doaj   +1 more source

Poor adherence to highly active antiretroviral therapy and associated factors among people living with HIV in Eastern Ethiopia

SAGE Open Medicine, 2022
Objective: Sustained adherence to highly active antiretroviral therapy is necessary to suppress viral replication and improve immunological and clinical outcomes.
Degu Tegegne, Galana Mamo, Belay Negash, Sisay Habte, Tesfaye Gobena, Shiferaw Letta   +5 more
doaj   +1 more source