Results 51 to 60 of about 8,514 (288)

Electroencephalographic Normalization as a Biomarker of Clinical Recovery in Down Syndrome Regression Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Down syndrome regression disorder is a syndrome characterized by subacute loss of cognitive, behavioral, and functional abilities in individuals with Down syndrome. Electroencephalography abnormalities are frequently observed during evaluation, but it remains unclear whether these findings represent a dynamic marker of disease ...
Jonathan D. Santoro, Mackenzie Silverman, Maeve C. Lucas, Mariam M. Yousuf, Samuel T. Otey, Stella V. Gray, Brittany Jordan, Madeline D. Kahan, Latanya D. Agurs, Michelle Van Hirtum Das, Deborah Holder, Devin King, Eileen A. Quinn, Ryan Kammeyer, Michael S. Rafii   +14 more
wiley   +1 more source

Anti-seizure medication discontinuation in pediatric epilepsy patients in pediatric neurology practice: A single center experience

Medicine Science
The objective of this study was to investigate the relapse rate and associated factors following the discontinuation of antiseizure medication in pediatric patients diagnosed with epilepsy.
Hilal Aydin, Ozlem Kemer Aycan, Oguzhan Korkut, Betul Tosun   +3 more
doaj   +1 more source

Etiology‐specific response to antiseizure medication in focal epilepsy [PDF]

, 2021
Objective: In focal epilepsy, data on the etiology-specific response to antiseizure medication (ASM) are surprisingly sparse. In this study, we sought to reappraise whether seizure outcome of pharmacological treatment is linked to the underlying etiology.
Kowski, Alexander B., Holtkamp, Martin, Doerrfuss, Jakob I.   +2 more
core   +1 more source

35 Individuals With HUWE1‐Related Neurodevelopmental Disorder and Suggested Clinical Evaluations

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT HUWE1 (HECT, UBA, and WWE Domain Containing E3 Ubiquitin Protein Ligase1, OMIM 300697), located at Xp11.22, encodes a ubiquitin ligase that is highly conserved across species. Genetic variants in HUWE1 described in multiple independent studies cause X‐linked intellectual disability, including in the patients identified by Juberg, Marsidi, and ...
Mindy H. Li, Deziree L. Coleman, Kelsey Hogan, Danielle Luz, Lindsay Bhandari, Newell Belnap, Tiffany Busa, Charles Coutton, Klaus Dieterich, Svetlana Gorokhova, Clara Hildebrandt, Rachel Logan, Milena Mariani, Manuela Morleo, Vincenzo Nigro, John Pappas, Rachel Rabin, Kelly Schoch, Angelo Selicorni, Vandana Shashi, Rebecca Spillmann, Jennifer Sullivan, Charlotte Tardy, Samantha A. Schrier Vergano, Brock Grill, Kristin Baranano   +25 more
wiley   +1 more source

Point‐of‐care electroencephalography enables rapid evaluation and management of non‐convulsive seizures and status epilepticus in the emergency department

Journal of the American College of Emergency Physicians Open, 2023
Objectives To describe our institutional experience with point‐of‐care electroencephalography (pocEEG) and its impact on the evaluation/management of suspected non‐convulsive seizures in the emergency department (ED).
Richard Kozak, Kapil Gururangan, Parshaw J. Dorriz, Matthew Kaplan   +3 more
doaj   +1 more source

Lamotrigine as an antiseizure medication in pregnancy

Seizure: European Journal of Epilepsy
To try to ascertain in APR data why lamotrigine was the preferred ASM in treating women with epilepsy, METHOD: Statistical analysis of foetal malformation and seizure free pregnancy occurrence rates associated with lamotrigine use in monotherapy and polytherapy RESULTS: Among commonly used ASMs, lamotrigine (4.6%) and levetiracetam (4.5%) in ...
Frank J.E. Vajda, Terence J. O’Brien, Janet E. Graham, Alison E. Hitchcock, Piero Perucca, Cecilie M. Lander, Mervyn J. Eadie   +6 more
openaire   +4 more sources

Sleep Disturbances in Adults With Tuberous Sclerosis Complex: Influences of Treatment and Clinical Features

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Tuberous sclerosis complex (TSC) is a genetic condition with multisystem neurocutaneous signs, including hamartomas, epilepsy, and neuropsychological difficulties. Although sleep disorders are increasingly recognized in TSC, they remain poorly described in adults.
Kirstin A. Risgaard, Laura Farach, Hope Northrup, Sarah L. Wilson, Deborah Pearson, Syed Hashmi, Kate Richardson   +6 more
wiley   +1 more source

Relapses, Comorbidities, and Predictors of Outcome in Anti‐GABAA Receptor Encephalitis

Annals of Neurology, EarlyView.
Objectives To characterize the magnetic resonance imaging (MRI) lesion dynamics, comorbidities, predictors of relapse, and outcomes in anti‐γ‐aminobutyric acid type A receptor (GABAAR) encephalitis, and assess the utility of LIM‐domain‐only‐protein 5 (LMO5) antibodies as tumor markers.
Claudia Papi, Chiara Milano, Laura Marmolejo, Ana Beatriz Serafim, Esther Aguilar, Mar Guasp, Elianet Fonseca, Mateus Mistieri Simabukuro, Raffaele Iorio, Yuki Fukami, Maria Lucia Schmitz Ferreira Santos, Takashi Miwa, Takashi Araga, Yuto Uchida, Masanori Kurihara, Satoshi Okada, Luz Victoria Garcia, Kenichi Kaida, Natalia Spinola Costa da Cunha, Alberto Vogrig, Florian Lamblin, Juna M. de Vries, Livia Almeida Dutra, Romana Höftberger, Maarten J. Titulaer, Jesús Planagumà, Lidia Sabater, Eugenia Martinez‐Hernandez, Thais Armangué, Francesc Graus, Takahiro Iizuka, Josep Dalmau, Marianna Spatola, Anti‐GABAAR encephalitis study group   +33 more
wiley   +1 more source

Vitamin D status of pediatric epilepsy patients and evaluation of affecting factors

Italian Journal of Pediatrics
Background The use of antiseizure medication in patients with epilepsy is one of the significant risk factors associated with abnormal vitamin D status.
Serap Bilge, Sema Nur Taşkın
doaj   +1 more source

Does Adjustment of Antiseizure Medication Regimen after Failed Epilepsy Surgery Improve Outcomes?

, 2023
Background and Objectives: After failed epilepsy surgery, patients often revert to an antiseizure medication (ASM) ASM regimen, which can be adjusted or optimized in three ways: increasing the dose, alternative therapy, and combination therapy.
Bin Zou, Xuan Zhai, Xinyu Dong, Lusheng Li, Difei Wang, Zaiyu Zhang, Yuxin Wu, Ping Liang, Haotian Tang, Hanli Qiu   +9 more
core   +1 more source