Results 61 to 70 of about 8,514 (288)

Continuous Versus Short EEG After Ischemic Stroke: What cEEG Adds for Detecting Abnormalities and Predicting Post‐Stroke Epilepsy

Annals of Neurology, EarlyView.
Objective The objective of this study was to quantify incremental diagnostic yield and prognostic value of continuous electroencephalography (cEEG; ≥12 hours) versus a 60‐minute short electroencephalography (sEEG) in predicting post‐stroke epilepsy (PSE) in patients without acute symptomatic seizures.
Kai Michael Schubert, Vijaya Dasari, Chiara Tatillo, Gilles Naeije, Sándor Beniczky, Carla Bentes, Marian Galovic, Nicolas Gaspard, Vineet Punia   +8 more
wiley   +1 more source

Gut–Brain Axis Modulation by Short‐Chain Fatty Acids Exerts Disease‐Modifying Effects in a Murine Model of Drug‐Resistant Epilepsy

Annals of Neurology, EarlyView.
Objective Drug‐resistant epilepsy (DRE) remains a clinical challenge, as therapies modifying disease trajectory are lacking. Increasing evidence implicates gut microbiota dysbiosis in epilepsy pathophysiology, with short‐chain fatty acids (SCFAs) emerging as key microbial metabolites with neuroprotective and anti‐inflammatory properties.
Akash A. Bera, Rossella Di Sapia, Greta Volpedo, Sneha Anand, Eray Sahin, Pasquale Baldassarre, Francesca Buffelli, Andrea Petretto, Chiara Lavarello, James D. Mills, Gabriele Cattaneo, Ilaria Craparotta, Eleonora Aronica, Antonella Riva, Pasquale Striano, Annamaria Vezzani, Teresa Ravizza   +16 more
wiley   +1 more source

First-line levetiracetam versus enzyme-inducing antiseizure medication in glioma patients with epilepsy

, 2022
Objective: This study aimed to directly compare the effectiveness of first-line monotherapy levetiracetam (LEV) versus enzyme-inducing antiseizure medications (EIASMs) in glioma patients.
Meer, P.B. van der, Italian League Epilepsy Brain Tumo, Koekkoek, J.A.F., Maschio, M., Dirven, L., Taphoorn, M.J.B.   +5 more
core   +1 more source

Longitudinal EpiTrack assessment of executive functions following vagus nerve stimulation therapy in patients with drug‐resistant epilepsy

Epilepsia Open
Objective To investigate executive functions and attention with repeated EpiTrack evaluations in a group of DR patients with drug‐resistant epilepsy (DRE) receiving vagus nerve stimulation (VNS) during a follow‐up duration of up to 5 years.
Niina Lähde, Pabitra Basnyat, Jani Raitanen, Kai Lehtimäki, Eija Rosti‐Otajärvi, Jukka Peltola   +5 more
doaj   +1 more source

Epilepsy characteristics in patients with muscle‐eye‐brain disease: A systematic review of electroclinical features

Epileptic Disorders, EarlyView.
Abstract Background and Objectives Muscle‐Eye‐Brain disease (MEB) is a dystroglycanopathy that belongs to the congenital muscular dystrophies. Central nervous system manifestations include congenital brain abnormalities, neurodevelopmental delay, and epilepsy, making it a rare but important cause of developmental and epileptic encephalopathy.
Stefania Kalampokini, Evripidis Pityrigkas, Eleni Liouta, Georgia Pepe, Vasiliki Poulidou, Martha Spilioti, Vasilios K. Kimiskidis   +6 more
wiley   +1 more source

“Homicide and Zonisamide”: a review of the literature and illustrative case report on second and third generation antiseizure medications and psychiatric effects

Frontiers in Psychiatry
IntroductionCerebral cavernous malformations (CCMs) are vascular lesions that can cause focal epilepsy due to local hemosiderin deposition, gliosis, and cortical irritation.
Stefanie Nguyen, Thomas C. Varkey, Briana Khan, M. Christian Cornelius   +3 more
doaj   +1 more source

Barriers and enablers to antiseizure medication adherence in children with Epilepsy:A systematic review using meta-ethnography

Adherence to antiseizure medications (ASMs) is essential for seizure control in children with epilepsy. However, multiple factors influence adherence, leading to varied treatment outcomes.
Stewart, Andy, Wright, David, Smith, Caroline, Kyeremaa, Eric Amankona Abrefa, Alorabi, Majed, Lawthom, Charlotte, Scott, Sion   +6 more
core   +2 more sources

A guide to neuromodulation in drug‐resistant epilepsy

Epileptic Disorders, EarlyView.
Abstract Neuromodulation is approved for the treatment of drug‐resistant epilepsy. It has been increasingly utilized over the past two decades with the approval of deep brain stimulation (DBS) and responsive neurostimulation (RNS) in addition to vagus nerve stimulation (VNS)—particularly in patients who are not deemed to be good resective surgical ...
Prachi Parikh, Irena Dolezawa, Manu Hegde, Lukas Imbach, Brian N. Lundstrom, Francesca Pizzo, Vikram R. Rao, Jaysingh Singh, Derek Southwell, Satsuke Watanabe, Birgit Frauscher   +10 more
wiley   +1 more source

Antiseizure Medications and Bone Health

Neurology and Therapy
Epilepsy frequently requires treatment with antiseizure medications (ASM). With the progressive rise in life expectancy in this population, patients are more exposed to potential undesirable effects, some of them on bone tissue. Here, we review current knowledge concerning the impact of ASM on bone biology.
Paula V. Gaete, Valentina Cuellar-Rodríguez, Carlos O. Mendivil   +2 more
openaire   +2 more sources

Prospective study of cenobamate on cognition, affectivity, and quality of life in focal epilepsy

Epilepsia Open
Objective Cenobamate is a recently approved antiseizure medication that proved to be safe and effective in randomized controlled trials. However, little is known about its impact on some areas frequently affected by epilepsy. For this reason, we explored
Judit Catalán‐Aguilar, Kevin G. Hampel, Irene Cano‐López, Mercedes Garcés, Alejandro Lozano‐García, Paula Tormos‐Pons, Esperanza González‐Bono, Vicente Villanueva   +7 more
doaj   +1 more source