Results 231 to 240 of about 443,792 (339)

Peptide-mediated Cell and In Vivo Delivery of Antisense Oligonucleotides and siRNA

Molecular Therapy: Nucleic Acids, 2012
Peter Järver, Thibault Coursindel, Samir EL Andaloussi, Caroline Godfrey, Matthew JA Wood, Michael J Gait   +5 more
doaj   +1 more source

Glucose Intake during the Neonatal Period Modulates the Central Melanocortin System with Breed-Specific Differences. [PDF]

J Poult Sci
Kimura K, Watanabe Y, Ashizawa S, Matsushita K, Nakao N, Ohta Y, Shiraishi JI.   +6 more
europepmc   +1 more source

AZD9150, a next-generation antisense oligonucleotide inhibitor of STAT3 with early evidence of clinical activity in lymphoma and lung cancer

Science Translational Medicine, 2015
D. Hong, R. Kurzrock, Youngsoo Kim, R. Woessner, A. Younes, J. Nemunaitis, N. Fowler, Tianyuan Zhou, Joanna Schmidt, Minji Jo, Samantha J. Lee, Mason Yamashita, S. G. Hughes, L. Fayad, S. Piha-Paul, M. V. Nadella, Morvarid Mohseni, D. Lawson, C. Reimer, D. Blakey, Xiaokun Xiao, J. Hsu, A. Revenko, B. Monia, A. Macleod   +24 more
semanticscholar   +1 more source

Annual Banned‐Substance Review 18th Edition—Analytical Approaches in Human Sports Drug Testing 2024/2025

Drug Testing and Analysis, EarlyView.
New insights into drug metabolism, distribution, elimination, and detection assays for drugs and methods of sports doping published between 2024 and 2025 are critically reviewed and evaluated in context with the Prohibited List 2025 as established by the World Anti‐Doping Agency.
Mario Thevis, Tiia Kuuranne, Hans Geyer
wiley   +1 more source

Bridge Nucleic Acid/DNA Gapmers as Potential Inhibitors of Bacterial Gene Expression by Multiple Antisense Mechanisms: An In Vitro Study. [PDF]

Molecules
Magaña AJ, Phan K, Lopez JA, Ramirez MS, Tolmasky ME.   +4 more
europepmc   +1 more source

Endogenous siRNAs Derived from a Pair of Natural cis-Antisense Transcripts Regulate Salt Tolerance in Arabidopsis

Cell, 2005
O. Borsani, Jianhua Zhu, P. Verslues, R. Sunkar, Jianhua Zhu   +4 more
semanticscholar   +1 more source

Epilepsy characteristics in patients with muscle‐eye‐brain disease: A systematic review of electroclinical features

Epileptic Disorders, EarlyView.
Abstract Background and Objectives Muscle‐Eye‐Brain disease (MEB) is a dystroglycanopathy that belongs to the congenital muscular dystrophies. Central nervous system manifestations include congenital brain abnormalities, neurodevelopmental delay, and epilepsy, making it a rare but important cause of developmental and epileptic encephalopathy.
Stefania Kalampokini, Evripidis Pityrigkas, Eleni Liouta, Georgia Pepe, Vasiliki Poulidou, Martha Spilioti, Vasilios K. Kimiskidis   +6 more
wiley   +1 more source

lncRNAs: key player in Aβ deposition. [PDF]

RNA Biol
Wang RM, Wang ZQ.
europepmc   +1 more source

miRNA‐dependent gene silencing involving Ago2‐mediated cleavage of a circular antisense RNA

EMBO Journal, 2011
T. B. Hansen, E. D. Wiklund, J. Bramsen, Sune B. Villadsen, A. Statham, S. Clark, J. Kjems   +6 more
semanticscholar   +1 more source

Evolution of the European Medicines Agency clinical guidelines for epilepsy drug development between 2010 and 2025: A comparative analysis by the ILAE Task Force on Regulatory Affairs

Epilepsia, EarlyView.
Abstract Objective The latest European Medicines Agency (EMA) guideline on the clinical investigation of medicines to treat epileptic disorders was adopted by the EMA Committee for Medicinal Products for Human Use in 2025. We compared this guideline with the previous version (2010), highlighting areas where significant revisions were introduced ...
Stéphane Auvin, Alexis Arzimanoglou, Jacqueline French, Kelly G. Knupp, Lieven Lagae, Eugen Trinka, Dennis Dlugos, Emilio Perucca   +7 more
wiley   +1 more source