Results 181 to 190 of about 131,722 (303)

Articoli Schwarz(strand_seclection) / Grishok(stRNA&RNAi) / Han(microprocessor) [PDF]

, 2012
Danielli, Alberto
core  

Endophytic and ectomycorrhizal, an overlooked dual ecological niche? Insights from natural environments and Russula species

New Phytologist, EarlyView.
Summary Ectomycorrhizal fungi (EcMF) are key components of temperate ecosystems, and recent studies suggest that they can also inhabit non‐EcM plant roots as endophytes. We aimed to (1) provide new evidence of EcMF colonization of non‐EcM hosts, (2) offer direct microscopic confirmation of such endophytism and (3) assess factors influencing ...
Liam Laurent‐Webb, Philippe Rech, Amélia Bourceret, Chloé Chaumenton, Aurélie Deveau, Laurent Genola, Mélanie Januario, Rémi Petrolli, Marc‐André Selosse   +8 more
wiley   +1 more source

Transcriptional Regulation of the Novel Theacrine Synthase Gene CsTcS2 by the CsTINY–CsWRKY33 Module Underpins Theacrine Biosynthesis in Camellia sinensis

Plant Biotechnology Journal, EarlyView.
ABSTRACT Theacrine (1,3,7,9‐tetramethyluric acid) is a purine alkaloid detected in multiple wild and specialised tea germplasms (Camellia sinensis) from South China, including Kucha. However, the molecular mechanisms governing its biosynthesis remain poorly understood. Here, we identify CsTcS2 as a novel theacrine synthase in tea plant.
Ting Wu, Lihua Zhu, Chenyu Shao, Siyi Xie, Na Li, Xinyu Li, Fang Wang, Lvwen Peng, Huiying Jin, Fanghuizi Shang, Jianan Huang, Zhonghua Liu, Na Tian, Shuoqian Liu   +13 more
wiley   +1 more source

Glycogen for Smyd3-antisense oligonucleotide delivery and enhanced liver cancer gene therapy. [PDF]

RSC Adv
Bai N, Huang Y, Shen J, Peng Y, Zhang H, Hou D.   +5 more
europepmc   +1 more source

Translating cardiovascular ion channel and Ca2+ signalling mechanisms into therapeutic insights

The Journal of Physiology, EarlyView.
Abstract figure legend This white paper integrates mechanistic discoveries across ion channel biology, Ca2+ signalling and multiscale cardiovascular physiology to highlight new opportunities for accelerating research and guiding next‐generation therapies. Printed with permission from ®Anita Impagliazzo Medical Illustration. [Correction added on 2 March
Silvia Marchianò, Miguel Martín‐Aragón Baudel, Charlotte E. R. Smith, Gonzalo Hernandez Hernandez, Donald M. Bers, Patrick M. Boyle, Dobromir Dobrev, Shanna Hamilton, Osama F. Harraz, Na Li, Thomas A. Longden, William E. Louch, Madeline Nieves‐Cintron, Matthew A. Nystoriak, Walter Lee Murfee, Przemysław B. Radwański, Swapnil K. Sonkusare, Manuel F. Navedo, Eleonora Grandi   +18 more
wiley   +1 more source

Antisense Oligonucleotide Therapy for Amyotrophic Lateral Sclerosis (ALS): An Umbrella Review. [PDF]

Cureus
Jeong E, Li D.
europepmc   +1 more source

Integrative genomic and functional characterization of ADAMTS3 reveals its inflammatory regulation via NF‐κB and STAT3 pathways in osteosarcoma

Journal of Cell Communication and Signaling, Volume 20, Issue 2, -Not available-.
Abstract Osteosarcoma (OS) is an aggressive bone malignancy characterized by genomic instability and extensive extracellular matrix (ECM) remodeling. Members of the ADAMTS family are matrix‐associated proteases implicated in tumorigenesis; however, their roles in OS remain poorly defined. This study provides a comprehensive genomic, transcriptomic, and
Ehed Muhammed Aymaz, Meltem Alper, Feyza Nur Sav, Tuğşen Aydemir, Feray Köçkar   +4 more
wiley   +1 more source

Antisense oligonucleotide-based switches for conditional translation of synthetic mRNA. [PDF]

Mol Ther Nucleic Acids
Combes F, Pettersson FJ, Bui TH.
europepmc   +1 more source

Eplontersen for Hereditary Transthyretin Amyloidosis With Polyneuropathy: An Exploratory Analysis of Treatment Effect in Male and Female Patients

Muscle &Nerve, Volume 73, Issue 6, Page 1118-1127, June 2026.
This exploratory analysis of data from the NEURO‐TTRansform trial evaluated sex‐specific responses in patients with ATTRv‐PN who had received eplontersen in NEURO‐TTRansform versus a historical placebo. Eplontersen can lead to substantial decreases in percentage serum TTR levels, arrest neuropathy impairment, and improve patient quality of life ...
Márcia Waddington Cruz, John L. Berk, Yeşim Parman, Morie Gertz, Sami Khella, Markus Weiler, T. Jesse Kwoh, Maksym Pola, Barry Reicher, Jonatan Nåtman, Noel R. Dasgupta, Jonas Wixner   +11 more
wiley   +1 more source

A sweet barrier to gene silencing: Glucose metabolism interferes with antisense oligonucleotide therapy. [PDF]

Mol Ther Nucleic Acids
Duan S, Zhang W, Cao H.
europepmc   +1 more source