Results 161 to 170 of about 270,275 (243)

Antisense oligonucleotide-based switches for conditional translation of synthetic mRNA. [PDF]

Mol Ther Nucleic Acids
Combes F, Pettersson FJ, Bui TH.
europepmc   +1 more source

Molecular impact of antisense oligonucleotide therapy in C9orf72-associated ALS. [PDF]

Cell
McEachin ZT, Chung M, Stratton SA, Han C, Kim WJ, Sheth U, Thomas EV, Issenberg E, Kamra T, Merino P, Levites Y, Raj N, Dammer EB, Duong DM, Ping L, Shantaraman A, Trautwig AN, Gadhavi J, Assefa E, Gearing M, Kelly KM, Roemer SF, DeTure M, Asress S, Kukar T, Fournier C, Dickson DW, Petrucelli L, Golde TE, Oskarsson B, Gendron TF, Seyfried NT, Glass JD.   +32 more
europepmc   +1 more source

A sweet barrier to gene silencing: Glucose metabolism interferes with antisense oligonucleotide therapy. [PDF]

Mol Ther Nucleic Acids
Duan S, Zhang W, Cao H.
europepmc   +1 more source

Gapmer Antisense Oligonucleotide Targeting E-Cadherin Rescues Abnormal Keratinization in X-Linked Ichthyosis Models. [PDF]

Biomol Ther (Seoul)
Kwak JH, Kwon TU, Kwon YJ, Park H, Kang YJ, Shin J, Chun YJ.   +6 more
europepmc   +1 more source

Targeted antisense oligonucleotide treatment rescues developmental alterations in spinal muscular atrophy organoids. [PDF]

Nat Commun
Faravelli I, Rinchetti P, Tambalo M, Simutin I, Mapelli L, Mancinelli S, Miotto M, Rizzuti M, D'Angelo A, Cordiglieri C, Forotti G, Peano C, Kunderfranco P, Calandriello L, Comi GP, Paraboschi E, Pali E, Beatrice F, D'Angelo E, Przedborski S, Nizzardo M, Lodato S, Corti S.   +22 more
europepmc   +1 more source

CD47 antisense oligonucleotide treatment improves glucose homeostasis and alleviates dyslipidemia in aged male mice. [PDF]

Aging (Albany NY)
Gwag T, Newcomb A, Otuagomah J, Murray S, Guo S, Tong S, Kern PA, Wang S.   +7 more
europepmc   +1 more source

A therapeutic antisense oligonucleotide encompassing 2'-<i>O</i>-methoxyethyl modification triggers unique perturbation of the transcriptome. [PDF]

NAR Mol Med
Ottesen EW, Murzyn WA, Kaas RL, Bertrand KJ, Payne JL, Singh RN.   +5 more
europepmc   +1 more source

Atrophin-1 antisense oligonucleotide provides robust protection from pathology in a fully humanized DRPLA model. [PDF]

Mol Ther Nucleic Acids
Smith VL, Gidi BZ, Bragg RM, Cantle JP, Ben-Varon A, Noble B, Prades S, Compton A, Greenfield J, Korecka JA, Gemos A, Yu T, Khurana V, Kordasiewicz HB, Zhao HT, Barker-Haliski M, Child DD, Carroll JB.   +17 more
europepmc   +1 more source

From Genomic Diagnosis to Personalized RNA Medicine: Advances in Next-Generation Sequencing and N-of-1 Antisense Oligonucleotide Therapies for Rare Genetic Diseases. [PDF]

Genes (Basel)
Rodriguez Carstens P, Moriyama H, Yokota T.   +2 more
europepmc   +1 more source