Results 171 to 180 of about 270,275 (243)

Correction: Antisense oligonucleotide targeting TARDBP-EGFR splicing axis inhibits progression of oral squamous cell carcinoma through ABCA1-regulated cholesterol efflux. [PDF]

Int J Oral Sci
Ni N, Wang M, Yuan Z, Zhang L, Cai J, Du Q, Li P, Gao C, Zhang H, Li Y, Yuan H.   +10 more
europepmc   +1 more source

Drug Candidate BIO101 for Spinal Muscular Atrophy as Monotherapy or Combined With the Antisense Oligonucleotide ASO-10-27. [PDF]

J Cachexia Sarcopenia Muscle
Bézier C, Cottin S, Hashemi PN, El Khoury M, Clerc Z, Balducci C, Sapaly D, Weill L, Lafont R, Veillet S, Dilda PJ, Charbonnier F, Latil M, Biondi O.   +13 more
europepmc   +1 more source

Safety, pharmacokinetics, and pharmacodynamics of the antisense oligonucleotide RO7239958 in healthy volunteers and adults with chronic hepatitis B infection. [PDF]

Antimicrob Agents Chemother
Geretti AM, Sostelly A, Buatois S, Lu S, Lemenuel A, Attley G, Bopst M, Alvarez-Sánchez R, Mueller H, Gane E.   +9 more
europepmc   +1 more source

Pharmacokinetics and Safety of Pelacarsen, a GalNAc₃-Conjugated Antisense Oligonucleotide Targeting Apo(a), in Participants With Mild Hepatic Impairment. [PDF]

Clin Transl Sci
Yan JH, Taylor AJ, Clough T, Burmeister-Getz E, Pazdirkova M, Russo C.   +5 more
europepmc   +1 more source

A splice-switching antisense oligonucleotide approach for pediatric genetic epilepsies

Dame HB, Kopalle H, Miñana B, Klaft Z, Fahey JB, McWatters DC, Rao V, Suresh R, Aigner S, Hammer MF, Yuskaitis CJ, Wong M, Teaney N, Zhang C, Thompson M, Lehner B, Bennett CF, Valcárcel J, Yeo GW, Burge CB, Dulla CG, Oudin MJ.   +21 more
europepmc   +1 more source

DDX5 mRNA-targeting antisense oligonucleotide as a new promising therapeutic in combating castration-resistant prostate cancer. [PDF]

Mol Ther
Le TK, Cherif C, Omabe K, Paris C, Lannes F, Audebert S, Baudelet E, Hamimed M, Barbolosi D, Finetti P, Bastide C, Fazli L, Gleave M, Bertucci F, Taïeb D, Rocchi P.   +15 more
europepmc   +1 more source

Comparison of <i>MALAT1</i> antisense oligonucleotide distribution following intracerebroventricular and lumbar intrathecal routes of administration. [PDF]

Mol Ther Nucleic Acids
Boyd MM, Mazur C, Pribnow K, Zanon RL, Adams E, DuGal J, Klein SK, Shafer LL.   +7 more
europepmc   +1 more source

<i>In vivo</i> delivery of a fluorogenic antisense oligonucleotide into human leukocytes in a humanized mouse model system. [PDF]

Mol Ther Methods Clin Dev
Seidel NB, Rout SS, Packard BZ, Lavender KJ.   +3 more
europepmc   +1 more source

Clinical considerations for the treatment of patients with familial chylomicronemia syndrome using a hepatic-targeted <i>APOC3</i> antisense oligonucleotide. [PDF]

Am J Prev Cardiol
Bajaj A, Oral EA, Brown A, Gaudet D, Alexander VJ, Karwatowska-Prokopczuk E, Baum SJ.   +6 more
europepmc   +1 more source