Abrogation of the Fc gamma receptor IIA-mediated phagocytic signal by stem-loop Syk antisense oligonucleotides. [PDF]
, 1996 Masashi Matsuda +5 more
openalex +1 more source
The role of UPR‐related long noncoding RNAs in development of endocrine resistance in breast cancer
International Journal of Cancer, EarlyView.Abstract Breast cancer patients who express estrogen receptor α (ER) typically receive endocrine therapy as a first‐line treatment. Most ER‐positive breast cancer patients initially respond to endocrine therapy, but up to 40% of patients develop resistance over time, and the main mechanism is aberrant activation of ER signaling pathways.
Wen Liu, Sahil Gupta, Sanjeev Gupta
wiley +1 more source
Antisense oligonucleotide therapies for monogenic disorders. [PDF]
Med GenetKrey-Grauert I, Ferro I, Wagner M.
europepmc +1 more source
Altered mRNA Splicing and Inhibition of Human E-selectin Expression by an Antisense Oligonucleotide in Human Umbilical Vein Endothelial Cells [PDF]
, 1996 Thomas P. Condon, C. Frank Bennett
openalex +1 more source
New insights into applications of base editor in hereditary disorders
Interdisciplinary Medicine, EarlyView.Abstract Hereditary disorders are a group of diseases caused by genetic mutations or chromosomal variations. Although the incidence of each genetic disorder is relatively low, patients affected by the disease generally experience a range of severe symptoms, including blindness, disability, and even premature death. In addition, the available treatments
Maoping Cai +8 more
wiley +1 more source
Synergistic inhibition of human cancer cell growth by cytotoxic drugs and mixed backbone antisense oligonucleotide targeting protein kinase A [PDF]
, 1997 Giampaolo Tortora +8 more
openalex +1 more source
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Pancreatic cancer (PC) is a highly aggressive malignancy of the digestive system. Recent studies have indicated that the long noncoding RNA SOX21‐AS1 is significantly upregulated in PC tissue samples. This study aims to elucidate the biological role and underlying molecular mechanisms of SOX21‐AS1 in PC progression. Quantitative real‐time PCR (
Han‐Bing Xu +3 more
wiley +1 more source
Interactions of antisense DNA oligonucleotide analogs with phospholipid membranes (liposomes).
, 1991 Saghir Akhtar +3 more
openalex +2 more sources
Prothymosin α antisense oligonucleotides induce apoptosis in HL-60 cells [PDF]
, 1999 Pilar Rodriguez Rodríguez +3 more
openalex +1 more source
Recent Advances in Injectable Hydrogel Biotherapeutics for Regenerative Dental Medicine
Macromolecular Bioscience, EarlyView.This review analyses multifunctional injectable hydrogels, natural or synthetic, physically or chemically crosslinked, that deliver exosomes, stem cells, and other bioactive cues to inflamed or damaged oral tissues. We discuss their immunomodulatory, antimicrobial, angiogenic, and osteogenic capacities, highlighting advances that enable regenerative ...
Renan Dal‐Fabbro +6 more
wiley +1 more source