Results 181 to 190 of about 124,170 (327)

Site-specific DNA cleavage by antisense oligonucleotides covalently linked to phenazine di-N-oxide.

, 1991
Koki Nagai, Sidney M. Hecht
openalex   +1 more source

Inhibition of the erbB-2 Tyrosine Kinase Receptor in Breast Cancer Cells by Phosphoromonothioate and Phosphorodithioate Antisense Oligonucleotides [PDF]

, 1996
James P. Vaughn, J. Stekler, Samuel H. Demirdji, Jane K. Mills, Marvin H. Caruthers, J. Dirk Iglehart, Jeffrey R. Marks   +6 more
openalex   +1 more source

Nature Inspired Delivery Vehicles for CRISPR‐Based Genome Editing

Small, EarlyView.
The review highlights nature‐inspired nanocarriers for CRISPR delivery, emphasizing viral vectors, extracellular vesicles, liposomes, and lipid nanoparticles. It discusses their roles in improving specificity, minimizing immunogenicity, and overcoming barriers in genome editing. Recent advancements, challenges, and therapeutic applications are explored,
Elizabeth Maria Clarissa, Mamata Karmacharya, Hyunmin Choi, Sumit Kumar, Yoon‐Kyoung Cho   +4 more
wiley   +1 more source

Antisense oligonucleotides to Cux-1, a Cut-related homeobox gene, cause increased apoptosis in mouse embryonic kidney cultures. [PDF]

, 1997
Susan E. Quaggin, Herman Yeger, Peter Igarashi   +2 more
openalex   +1 more source

A Method for High‐Throughput Screening of Monoclonal Antibody Internalization Using a DNA/Protein Molecular Staple

Small Methods, EarlyView.
Internalization of antibodies plays a critical role in targeted drug delivery and the activity of antibody therapeutics. A simple, one‐pot, chemical modification free approach is developed to quantify antibody internalization into cells. Abstract The use of monoclonal antibodies (mAbs) as therapeutics or for targeted delivery to specific cells is ...
Lara M. Mollé, Cameron H. Smyth, Bruna Rossi Herling, Daniel Yuen, Angus P.R. Johnston   +4 more
wiley   +1 more source

Expansion of Splice-Switching Therapy with Antisense Oligonucleotides. [PDF]

Int J Mol Sci
Takeshima Y.
europepmc   +1 more source

Abrogation of TGF-β by antisense oligonucleotides modulates expression of VEGF and increases angiogenic potential in isolated fibroblasts from radiated skin

, 1998
Riedel
openalex   +2 more sources

Oligonucleotides Tethered to a Short Polyguanylic Acid Stretch Are Targeted to Macrophages: Enhanced Antiviral Activity of a Vesicular Stomatitis Virus-Specific Antisense Oligonucleotide [PDF]

, 1999
Vikram Prasad, Shehla Hashim, Amitabha Mukhopadhyay, Sandip K. Basu, Rajendra P. Roy   +4 more
openalex   +1 more source

“Lock and Key”: Binding Behavior of Malachite Green and Functional Nucleic Acids and Their Multidimensional Applications

Small Structures, EarlyView.
The review comprehensively summarizes the binding behaviors and multidimensional applications of malachite green with diverse functional nucleic acids. By integrating structural mechanisms, comparative analysis, and application strategies across eight domains, it provides theoretical guidance and future perspectives for developing intelligent nucleic ...
Keren Chen, Yangzi Zhang, Qian Yang, Longjiao Zhu, Wentao Xu   +4 more
wiley   +1 more source

SNA-modified antisense oligonucleotides: A new pathway for renal targeting? [PDF]

Mol Ther Nucleic Acids
Dumoulin B, Yamada K, Susztak K.
europepmc   +1 more source