Results 191 to 200 of about 72,467 (253)

Targeting FANCM using the antisense oligonucleotides to treat the ALT-positive cancers. [PDF]

Mol Ther Nucleic Acids
Naji S, Tong C, Ragupathi A, Xiao M, Zhang D.   +4 more
europepmc   +1 more source

A Novel AP2/ERF Transcription Factor Controls Trichome Initiation and Fruit Development in Cucumber

Plant Biotechnology Journal, EarlyView.
ABSTRACT Trichomes, the hair‐like outgrowths of the plant epidermis, are critical for defence, reproduction and development. However, the underlying molecular mechanisms governing their initiation remain elusive. Here, we identified CsGL2, an AP2/ERF transcription factor, as a key integrator controlling trichome initiation and fruit development in ...
Haifan Wen, Hui Du, Siqi Wang, Yiqun Weng, Juan Liu, Huanle He, Run Cai, Jian Pan, Junsong Pan   +8 more
wiley   +1 more source

Clinical applications of exon-skipping antisense oligonucleotides in neuromuscular diseases. [PDF]

Mol Ther
Torres-Masjoan L, Aguti S, Zhou H, Muntoni F.   +3 more
europepmc   +1 more source

Liver-specific delivery of MDM2 antisense oligonucleotides counteracts diet-induced metabolic-dysfunction-associated steatotic liver diseases. [PDF]

Mol Ther Nucleic Acids
Hoque MM, Kong M, Yuan X, Zhou X, Ting-Yuan Yeh S, Long K, Lin H, Yip Cheng KK.   +7 more
europepmc   +1 more source

Identifying antisense oligonucleotides for targeted inhibition of insulin receptor isoform A. [PDF]

Front Oncol
Galifi CA, Dikdan RJ, Kantak D, Bulatowicz JJ, Maingrette K, Gunderson SI, Wood TL.   +6 more
europepmc   +1 more source

Targeting FANCM by antisense oligonucleotides in ALT-positive cancers. [PDF]

Mol Ther Nucleic Acids
Tieo G, Bao Ying Lim N, Lim KW, Dröge P, Phan AT, Jeitany M.   +5 more
europepmc   +1 more source

The impact of chemical modifications of antisense oligonucleotides on CTX-M-15 β-lactamase target affinity and expression of ceftriaxone-resistant <i>Escherichia coli</i>. [PDF]

NAR Mol Med
Barry H, Scillia L, Gaubert A, Amrane S, Vialet B, Bégu D, Barthélémy P, Arpin C, Kauss T.   +8 more
europepmc   +1 more source

Unraveling and controlling late-onset neurotoxicity of antisense oligonucleotides through strategic chemical modifications. [PDF]

Mol Ther Nucleic Acids
Kuroda T, Yoshioka K, Mon SSL, Katsuyama M, Sato K, Isogai E, Yoshida-Tanaka K, Iwata-Hara R, Yamaguchi T, Obika S, Yokota T.   +10 more
europepmc   +1 more source

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Antisense Oligonucleotides

Nephron Experimental Nephrology, 1998
Antisense technology was developed to inhibit gene expression by utilizing an oligonucleotide complementary to the mRNA which encodes the target gene. There are a few possible mechanisms for the inhibitory effects of antisense oligonucleotides. Among them, degradation of mRNA by RNase H is considered to be the major mechanism of action for antisense ...
N, Kashihara, Y, Maeshima, H, Makino
openaire   +4 more sources