Results 211 to 220 of about 125,197 (343)

Mechanism of Antisense Oligonucleotide Interaction with Natural RNAs [PDF]

, 2011
Roman N. Serikov, Vladislav Petyuk, Yu. Vorobijev, Vladimir V. Koval, Olga S. Fedorova, Valentin V. Vlassov, Marina A. Zenkova   +6 more
openalex   +1 more source

Protein production is an early biomarker for RNA‐targeted therapies [PDF]

, 2018
Alex, Jacob, Barthélemy, Nicolas, Bateman, Randall J, Bollinger, James G, Cole, Tracy, Kordasiewicz, Holly B, Miller, Timothy M, Sato, Chihiro, Schoch, Kathleen M, Self, Wade K, Swayze, Eric   +10 more
core   +2 more sources

ARF6 integrates auxin and gibberellin signaling to promote stone cell lignification in pear via the HB49‐MYB169 module

New Phytologist, EarlyView.
Summary Stone cells originate from secondary cell wall thickening and contain abundant lignin. Their excessive accumulation compromises pear fruit quality, yet the endogenous hormonal mechanisms governing stone cell formation remain unclear. Here, co‐expression network analysis using transcriptome data – the flesh of 206 sand pear accessions sampled at
Yanfei Shan, Shulin Chen, Jianfa Cai, Zheng Zhou, Chong Pan, Jiahao Liu, Pengfei Zheng, Cheng Li, Yueyuan Liu, Cheng Xue, Jun Wu   +10 more
wiley   +1 more source

Design of antisense oligonucleotides

Folia Pharmacologica Japonica, 2016
Satoshi, Obika, Yuuya, Kasahara
openaire   +3 more sources

Endophytic and ectomycorrhizal, an overlooked dual ecological niche? Insights from natural environments and Russula species

New Phytologist, EarlyView.
Summary Ectomycorrhizal fungi (EcMF) are key components of temperate ecosystems, and recent studies suggest that they can also inhabit non‐EcM plant roots as endophytes. We aimed to (1) provide new evidence of EcMF colonization of non‐EcM hosts, (2) offer direct microscopic confirmation of such endophytism and (3) assess factors influencing ...
Liam Laurent‐Webb, Philippe Rech, Amélia Bourceret, Chloé Chaumenton, Aurélie Deveau, Laurent Genola, Mélanie Januario, Rémi Petrolli, Marc‐André Selosse   +8 more
wiley   +1 more source

Restoring chloride efflux in cystic fibrosis with TMEM16a antisense oligonucleotides. [PDF]

Mol Ther
Mitri C, Rousselet N, Bardin P, Dias Wickramanayaka M, Foussignière T, Dupuis G, Leblanc M, Gournet V, Sonneville F, Corvol H, Tabary O.   +10 more
europepmc   +1 more source

Transcriptional Regulation of the Novel Theacrine Synthase Gene CsTcS2 by the CsTINY–CsWRKY33 Module Underpins Theacrine Biosynthesis in Camellia sinensis

Plant Biotechnology Journal, EarlyView.
ABSTRACT Theacrine (1,3,7,9‐tetramethyluric acid) is a purine alkaloid detected in multiple wild and specialised tea germplasms (Camellia sinensis) from South China, including Kucha. However, the molecular mechanisms governing its biosynthesis remain poorly understood. Here, we identify CsTcS2 as a novel theacrine synthase in tea plant.
Ting Wu, Lihua Zhu, Chenyu Shao, Siyi Xie, Na Li, Xinyu Li, Fang Wang, Lvwen Peng, Huiying Jin, Fanghuizi Shang, Jianan Huang, Zhonghua Liu, Na Tian, Shuoqian Liu   +13 more
wiley   +1 more source

Targeting rare splicing defects: Antisense oligonucleotides offer a therapeutic strategy in FRDA. [PDF]

Mol Ther Nucleic Acids
Kerkhof LMC, Buijsen RAM.
europepmc   +1 more source

Long-term rescue of vision with antisense oligonucleotides in a mouse model of Usher syndrome

, 2018
Jennifer J Lentz, Russell J. Amato, Robert F. Rosencrans, Francine M. Jodelka, Frederic Depreux, Bhagwat V. Alapure, Nicolás G. Bazán, Frank Rigo, Michelle L. Hastings   +8 more
openalex   +1 more source

Translating cardiovascular ion channel and Ca2+ signalling mechanisms into therapeutic insights

The Journal of Physiology, EarlyView.
Abstract figure legend This white paper integrates mechanistic discoveries across ion channel biology, Ca2+ signalling and multiscale cardiovascular physiology to highlight new opportunities for accelerating research and guiding next‐generation therapies. Printed with permission from ®Anita Impagliazzo Medical Illustration. [Correction added on 2 March
Silvia Marchianò, Miguel Martín‐Aragón Baudel, Charlotte E. R. Smith, Gonzalo Hernandez Hernandez, Donald M. Bers, Patrick M. Boyle, Dobromir Dobrev, Shanna Hamilton, Osama F. Harraz, Na Li, Thomas A. Longden, William E. Louch, Madeline Nieves‐Cintron, Matthew A. Nystoriak, Walter Lee Murfee, Przemysław B. Radwański, Swapnil K. Sonkusare, Manuel F. Navedo, Eleonora Grandi   +18 more
wiley   +1 more source