Results 191 to 200 of about 124,170 (327)

Design, biochemical, biophysical and biological properties of cooperative antisense oligonucleotides [PDF]

, 1995
Ekambar R. Kandimalla, Adrienne Manning, Christopher S. Lathan, Randal A. Byrn, Sudhir Agrawal   +4 more
openalex   +1 more source

Protein production is an early biomarker for RNA‐targeted therapies [PDF]

, 2018
Alex, Jacob, Barthélemy, Nicolas, Bateman, Randall J, Bollinger, James G, Cole, Tracy, Kordasiewicz, Holly B, Miller, Timothy M, Sato, Chihiro, Schoch, Kathleen M, Self, Wade K, Swayze, Eric   +10 more
core   +2 more sources

Perineural Invasion in Pancreatic Ductal Adenocarcinoma: Recapitulating Its Importance and Defining Future Directions

United European Gastroenterology Journal, EarlyView.
ABSTRACT Pancreatic ductal adenocarcinoma (PDAC) remains one of the most lethal malignancies, mainly due to its aggressive nature, early metastasis, diagnosis at late stages, and limited response to systemic anticancer therapy. Perineural invasion (PNI), defined as the infiltration of neoplastic cells along nerve fibers and within nerve sheaths, is ...
Martin Lovecek, Esra Dirimtekin, Ingrid Garajová, Giulia Gasparini, Stefano Crippa, Elisa Giovannetti, Dana Sochorova, Carmen Mota Reyes, Ihsan Ekin Demir, Pinar Uysal‐Onganer, on behalf TRANSPAN PNI Group   +10 more
wiley   +1 more source

Tofersen and other antisense oligonucleotides in ALS. [PDF]

Ther Adv Neurol Disord
Ludolph A, Wiesenfarth M.
europepmc   +1 more source

Proliferative effect of high glucose is modulated by antisense oligonucleotides against fibronectin in rat endothelial cells [PDF]

, 1997
Sayon Roy, Timothy P. Roth
openalex   +1 more source

Full‐length transcriptome profiling of true bug mitochondrial genomes reveals the unique transcriptional regulation during insect evolution

Insect Science, EarlyView.
The mitogenome was transcribed into complete primary polycistrons on both strands. The heteropteran mitochondrial transcription termination factor (HmTTF) functions as a bidirectional attenuator rather than a terminator, and co‐evolution of HmTTF and the binding sites was observed.
Shiwen Xu, Yuange Duan, Ling Ma, Qiaoqiao Liu, Fan Song, Wanzhi Cai, Hu Li   +6 more
wiley   +1 more source

Targeting FANCM using the antisense oligonucleotides to treat the ALT-positive cancers. [PDF]

Mol Ther Nucleic Acids
Naji S, Tong C, Ragupathi A, Xiao M, Zhang D.   +4 more
europepmc   +1 more source

Non‐Coding RNAs in Breast Cancer Radioresistance: Mechanisms, Functional Roles and Translational Potentials

Cell Proliferation, EarlyView.
Non‐coding RNAs (ncRNAs) regulate breast cancer radioresistance via cell cycle, DNA repair and tumour microenvironment pathways. Targeting ncRNAs (e.g., HOTAIR and miR‐155) with RNA‐based therapies (ASOs and CRISPR) shows promise but faces delivery challenges.
Xiaohui Zhao, Yuting Qiu, Jie Chen, Danni Wang, Zairui Wang, Shuang Ma, Yimin Liu, Guoying Liu, Zhuofei Bi   +8 more
wiley   +1 more source

Identifying antisense oligonucleotides for targeted inhibition of insulin receptor isoform A. [PDF]

Front Oncol
Galifi CA, Dikdan RJ, Kantak D, Bulatowicz JJ, Maingrette K, Gunderson SI, Wood TL.   +6 more
europepmc   +1 more source

Properties of circular dumbbell RNA/DNA chimeric oligonucleotides containing antisense phosphodiester oligonucleotides [PDF]

, 1999
W.-S. Park, Naoko Miyano‐Kurosaki, Tatsuya Abé, Kenichi Takai, Hiroaki Takaku   +4 more
openalex   +1 more source