Altered mRNA Splicing and Inhibition of Human E-selectin Expression by an Antisense Oligonucleotide in Human Umbilical Vein Endothelial Cells [PDF]
Thomas P. Condon, C. Frank Bennett
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Nature Inspired Delivery Vehicles for CRISPR‐Based Genome Editing
The review highlights nature‐inspired nanocarriers for CRISPR delivery, emphasizing viral vectors, extracellular vesicles, liposomes, and lipid nanoparticles. It discusses their roles in improving specificity, minimizing immunogenicity, and overcoming barriers in genome editing. Recent advancements, challenges, and therapeutic applications are explored,
Elizabeth Maria Clarissa+4 more
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Synergistic inhibition of human cancer cell growth by cytotoxic drugs and mixed backbone antisense oligonucleotide targeting protein kinase A [PDF]
Giampaolo Tortora+8 more
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NIR‐mediated photo‐switching drug delivery system for the remote‐control differentiation of NSCs. Left: NIR‐mediated curcumin release is induced by NIR‐to‐UV photon upconversion in a photo‐controllable manner. Curcumin is bound in the minor groove of the synthesized DNA construct containing AAP photo‐switchers. Right: The rational design of several AAP
Thanapat Pongkulapa+8 more
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Interactions of antisense DNA oligonucleotide analogs with phospholipid membranes (liposomes).
Saghir Akhtar+3 more
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Prothymosin α antisense oligonucleotides induce apoptosis in HL-60 cells [PDF]
Pilar Rodriguez Rodríguez+3 more
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Nucleic Acid‐Modified Nanoparticles for Cancer Therapeutic Applications
Nucleic acid‐modified nanoparticles act as functional hybrids for chemodynamic, photodynamic, photothermal, and gene therapy of cancer cells. These are exemplified with aptamer‐modified catalytic nanoparticles, photosensitizer‐oligonucleotide functionalized nanoparticles, drug‐loaded stimuli‐responsive nucleic acid‐caged nanoparticle carriers, and ...
Yunlong Qin+2 more
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Sustained reduction of neointima with c-myc antisense oligonucleotides in saphenous vein grafts [PDF]
John D. Mannion+5 more
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Cardiovascular and Metabolic Effects of ANGPTL3 Antisense Oligonucleotides
M. Graham+17 more
semanticscholar +1 more source
Long non‐coding RNAs (lncRNAs) are receiving increasing attention as biomarkers for cancer diagnosis and therapy, highlighting the urgent need for computational methods to accelerate their comprehensive discovery. Here, to better predict and provide functional insight into cancer lncRNAs, a novel interpretable machine‐learning method (POCALI) is ...
Ziyan Rao+5 more
wiley +1 more source