Results 191 to 200 of about 275,477 (365)

Nature Inspired Delivery Vehicles for CRISPR‐Based Genome Editing

open access: yesSmall, EarlyView.
The review highlights nature‐inspired nanocarriers for CRISPR delivery, emphasizing viral vectors, extracellular vesicles, liposomes, and lipid nanoparticles. It discusses their roles in improving specificity, minimizing immunogenicity, and overcoming barriers in genome editing. Recent advancements, challenges, and therapeutic applications are explored,
Elizabeth Maria Clarissa   +4 more
wiley   +1 more source

Synergistic inhibition of human cancer cell growth by cytotoxic drugs and mixed backbone antisense oligonucleotide targeting protein kinase A [PDF]

open access: bronze, 1997
Giampaolo Tortora   +8 more
openalex   +1 more source

NIR‐Induced Photoswitching Hybrid DNA Nanoconstruct‐Based Drug Delivery System for Spatiotemporal Control of Stem Cell Fate

open access: yesSmall, EarlyView.
NIR‐mediated photo‐switching drug delivery system for the remote‐control differentiation of NSCs. Left: NIR‐mediated curcumin release is induced by NIR‐to‐UV photon upconversion in a photo‐controllable manner. Curcumin is bound in the minor groove of the synthesized DNA construct containing AAP photo‐switchers. Right: The rational design of several AAP
Thanapat Pongkulapa   +8 more
wiley   +1 more source

Prothymosin α antisense oligonucleotides induce apoptosis in HL-60 cells [PDF]

open access: bronze, 1999
Pilar Rodriguez Rodrí­guez   +3 more
openalex   +1 more source

Nucleic Acid‐Modified Nanoparticles for Cancer Therapeutic Applications

open access: yesSmall, EarlyView.
Nucleic acid‐modified nanoparticles act as functional hybrids for chemodynamic, photodynamic, photothermal, and gene therapy of cancer cells. These are exemplified with aptamer‐modified catalytic nanoparticles, photosensitizer‐oligonucleotide functionalized nanoparticles, drug‐loaded stimuli‐responsive nucleic acid‐caged nanoparticle carriers, and ...
Yunlong Qin   +2 more
wiley   +1 more source

Sustained reduction of neointima with c-myc antisense oligonucleotides in saphenous vein grafts [PDF]

open access: bronze, 1998
John D. Mannion   +5 more
openalex   +1 more source

Cardiovascular and Metabolic Effects of ANGPTL3 Antisense Oligonucleotides

open access: yesNew England Journal of Medicine, 2017
M. Graham   +17 more
semanticscholar   +1 more source

POCALI: Prediction and Insight on CAncer LncRNAs by Integrating Multi‐Omics Data with Machine Learning

open access: yesSmall Methods, EarlyView.
Long non‐coding RNAs (lncRNAs) are receiving increasing attention as biomarkers for cancer diagnosis and therapy, highlighting the urgent need for computational methods to accelerate their comprehensive discovery. Here, to better predict and provide functional insight into cancer lncRNAs, a novel interpretable machine‐learning method (POCALI) is ...
Ziyan Rao   +5 more
wiley   +1 more source

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