Results 221 to 230 of about 124,170 (327)

Inhibition of Antigen-Induced Eosinophilia and Late Phase Airway Hyperresponsiveness by an IL-5 Antisense Oligonucleotide in Mouse Models of Asthma [PDF]

, 2000
James G. Karras, Kathy McGraw, Robert A. McKay, Scott Cooper, Dmitri Lerner, Tao Lü, Christoph Walker, Nicholas M. Dean, Brett P. Monia   +8 more
openalex   +1 more source

The Genetic Blueprint of Obesity: From Pathogenesis to Novel Therapies

Obesity Reviews, EarlyView.
ABSTRACT Obesity is a chronic metabolic disease characterized by disturbances in energy homeostasis, leading to excessive fat accumulation. The pathogenesis of the disease is shaped by a complex interplay of genetic, epigenetic, biological, psychological, and environmental factors.
Gašper Tonin, Stjepan Eržen, Zala Mlinarič, Dubravka Jurišić Eržen, Simon Horvat, Tanja Kunej, Jasna Klen   +6 more
wiley   +1 more source

Modulating immune responses in alopecia: therapeutic insights and potential targets of antisense oligonucleotides. [PDF]

BMC Immunol
Begum S, Hossain MJ, Kim I, Min HS, Lim YN, Cho HJ, Ryu JH.   +6 more
europepmc   +1 more source

Antisense oligonucleotides targeted against protein kinase c α inhibit proliferation of cultured avian myoblasts [PDF]

, 2000
Daniela Andrea Capiati, Guillermo Vázquez, María T. Tellez de Iñon, R. Boland   +3 more
openalex   +1 more source

Differentiation Trajectory of Virus‐Induced Tumour Cells in Rice Revealed by Single‐Cell RNA Sequencing

Plant Biotechnology Journal, EarlyView.
ABSTRACT Many plant viruses trigger abnormal differentiation and development of host cells, causing distinct symptoms. Here, in a single‐cell RNA sequence analysis, we find transcriptional heterogeneity between cells from rice leaf sheaths that are infected with rice black streaked dwarf virus (RBSDV) and from those that are virus‐free.
Nan Wu, Lu Gan, Qingqing Suo, Fei Yang, Wenwen Liu, Xifeng Wang, Huaibing Jin   +6 more
wiley   +1 more source

Magnetic-Guided Delivery of Antisense Oligonucleotides for Targeted Transduction in Multiple Retinal Explant and Organoid Models. [PDF]

Adv Sci (Weinh)
Ye X, Chen S, Xiong W, Wang F, Chan HF, Lai H, Guo X, Yang T, Shen S, Chen H, Wang W, Liu GS, Guo Y, Chen J.   +13 more
europepmc   +1 more source

pseudo‐GhFAD2‐1 Is a lncRNA Involved in Regulating Cottonseed Oleic and Linoleic Acid Ratios and Seed Size in Gossypium hirsutum

Plant Biotechnology Journal, EarlyView.
ABSTRACT Long non‐coding RNAs (lncRNAs), defined as transcripts > 200 nt without protein‐coding capacity, play crucial regulatory roles in plant growth and development. While numerous lncRNAs exist in plants including cotton (Gossypium spp.), few are functionally characterised. G. hirsutum serves as both a premier fibre crop and significant oil source,
Haihong Chen, Yanjun Li, XianPeng Xiong, Xuan Liu, Fei Xue, Jie Sun, Qian‐Hao Zhu, Feng Liu   +7 more
wiley   +1 more source

RNA G‑Quadruplex Reprogramming with Guanine-Rich Antisense Oligonucleotides Inhibits Monoamine Oxidase B's Translation. [PDF]

ACS Bio Med Chem Au
Turcotte MA, Perreault JP.
europepmc   +1 more source

Metabolomics and Transcriptomic Analysis Revealed the Response Mechanism of Maize to Saline‐Alkali Stress

Plant Biotechnology Journal, EarlyView.
ABSTRACT Saline‐alkali stress inhibited the normal growth and development of plants, which seriously restricted the yield of crops. Maize is one of the most important crops in the world. However, the mechanism of maize in response to saline‐alkali stress is still largely unknown.
Chunlai Wang, Xiaotong Wei, Yimeng Wang, Chenyang Wu, Peng Jiao, Zhenzhong Jiang, Siyan Liu, Yiyong Ma, Shuyan Guan   +8 more
wiley   +1 more source

Clinical Applications of Antisense Oligonucleotides in Cancer: A Focus on Glioblastoma. [PDF]

Cells
Khuu A, Verreault M, Colin P, Tran H, Idbaih A.   +4 more
europepmc   +1 more source