Results 281 to 290 of about 275,477 (365)

In vivo scintillation imaging of 131I-labelled c-myc antisense oligonucleotides after arterial transfection

, 1996
Rémi Martel, Angelica Fleser, Neil Hartman, Jean‐Paul Soucy, Martin Bouchard, Pierre Voisine, Guy Leclerc   +6 more
openalex   +1 more source

RNA therapeutics: beyond RNA interference and antisense oligonucleotides

Nature reviews. Drug discovery, 2012
R. Kole, A. Krainer, S. Altman
semanticscholar   +1 more source

Erratum: <i>In vivo</i> efficacy and safety of systemically administered serinol nucleic acid-modified antisense oligonucleotides in mouse kidney. [PDF]

Mol Ther Nucleic Acids
Tsuboi T, Hattori K, Ishimoto T, Imai K, Doke T, Hagita J, Ariyoshi J, Furuhashi K, Kato N, Ito Y, Kamiya Y, Asanuma H, Maruyama S.   +12 more
europepmc   +1 more source

Targeting the Liver Serine Protease TMPRSS6 Ameliorates Steatosis and Attenuates Fibrosis in Experimental MASLD

Liver International, Volume 45, Issue 7, July 2025.
ABSTRACT Background and Aims Metabolic dysfunction–associated steatotic liver disease (MASLD) is the most common cause of liver disease and a leading contributor to liver‐related morbidity and mortality. Currently, no pharmacological approach has demonstrated consistent and long‐lasting benefits across all patients.
Mariateresa Pettinato, Valeria Furiosi, Rossana Carleo, Letizia Bavuso Volpe, Shuling Guo, Valeria Mannella, Giovanna Musco, Enrica Gilberti, Giuseppe De Palma, Giorgia Federico, Francesca Carlomagno, Alessandro Cherubini, Serena Pelusi, Anxhela Dano, Antonella Nai, Luca Valenti, Sandro Altamura, Alessia Pagani, Laura Silvestri   +18 more
wiley   +1 more source

New Transferrin Receptor‐Targeting Conjugate Effectively Delivers DNA to Mouse Brain

Angewandte Chemie, Volume 137, Issue 24, June 10, 2025.
We present a novel RNA aptamer targeting the transferrin receptor (TfR), conjugated with DSPE lipid, which achieves remarkably efficient brain uptake, reaching brain‐to‐serum ratios as high as 6.5. Through fluorescence imaging and polymerase‐chain reaction analyses, we verify that this new conjugate successfully delivers a substantial amount of DNA ...
Min‐sun Song, Adrian H. Bustos, Lise Bastue, Justas Mikutavicius, Piotr Swiderski, Kelly J. Clemens, Nagy Habib, John Rossi, Kira Astakhova   +8 more
wiley   +2 more sources

Specific blockade of plasma membrane Ca2+ pump by antisense-oligonucleotides.

, 1996
Ken‐Ichi Furukawa, Miwa Shiratori, Satoshi Sasamura, Yasushi Ohizumi   +3 more
openalex   +1 more source

PLP1-Targeting Antisense Oligonucleotides Improve FOXG1 Syndrome Mice. [PDF]

Int J Mol Sci
Tan DCS, Jung S, Deng Y, Morey N, Chan G, Bongers A, Ke YD, Ittner LM, Delerue F.   +8 more
europepmc   +1 more source

Natural variation of CsUGT71A60 determines growth and cold tolerance via regulating cytokinin glycosylation in Camellia sinensis

Plant Biotechnology Journal, Volume 23, Issue 7, Page 2809-2823, July 2025.
Summary Cold stress severely limits tea plant (Camellia sinensis) productivity, yet the molecular mechanisms underlying cold adaptation remain elusive. Here, we identified a cold‐inducible glycosyltransferase, CsUGT71A60, through integrative genome‐wide association studies (GWAS) and proteomic profiling.
Mingyue Zhao, Jingming Wang, Xinyuan Hao, Jieyang Jin, Junwei Tang, Yueyue Wang, Mengting Zhang, Tingting Jing, Wilfried Schwab, Ting Gao, Xinchao Wang, Chuankui Song   +11 more
wiley   +1 more source

c-fos antisense oligonucleotide infusion into mouse striatum blocks methamphetamine-induced locomotor activity in a reversible manner

, 1996
Tadashi Umekage, Misako Namima, Kouji Fukushima, Souhei Sugita, Yasuhiro Watanabe   +4 more
openalex   +1 more source

uORF-targeting steric block antisense oligonucleotides do not reproducibly increase RNASEH1 expression. [PDF]

Mol Ther Nucleic Acids
Ahlskog N, Svrzikapa N, Abuhamdah R, Kye M, Jad Y, Feng N, Hanson B, Wood MJA, Roberts TC.   +8 more
europepmc   +1 more source